Published 4 September 2019 Missing data are unavoidable in epidemiological research, potentially leading to bias and loss of precision. Multiple imputation (MI) is widely advocated as an improvement over complete case analysis (CCA). However, contrary to widespread belief, CCA is preferable to MI in some situations. New publication in International Journal of EpidemiologyRead more here

https://www.lupop.lu.se/article/accounting-missing-data-statistical-analyses-multiple-imputation-not-always-answe - 2025-01-10

Published 5 September 2019 The use of oral anticoagulants is rarer in children than adults, but studies indicate that their paediatric use is increasing. Warfarin has been used in children, at the discretion of the treating physician, but both the number of children and the data on its use are limited New publication in Acta Paediatr.Read more here

https://www.lupop.lu.se/article/establishing-regional-paediatric-registry-improved-overview-and-detection-side-effects-children - 2025-01-10

Published 6 September 2019 Because of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer. Previous register studies indicate increased CM risk among children conceived after paternal cancer but lack data on oncological treatment. Increased CM risk was recently reported in chil

https://www.lupop.lu.se/article/cancer-therapy-and-risk-congenital-malformations-children-fathered-men-treated-testicular-germ-cell - 2025-01-10

Published 2 September 2019 RDA 14th Plenary in Finland brings together data experts in research, industry and policy-making from all around the world and from all disciplines under the theme Data Makes the Difference. Read more here.

https://www.lupop.lu.se/article/research-data-alliance-14th-plenary - 2025-01-10

Published 3 September 2019 A fully fledged 5-day training event which will provide the much needed foundational skills for competent data stewards and data managers in the Nordic countries with knowledge of the FAIR principles and their application. The course will be held by two trainers from GO-FAIR and provides a broad but fairly technical introduction to data stewardship. Read more here.

https://www.lupop.lu.se/article/fair-data-stewardship-supporting-fair-data-interoperability - 2025-01-10

Published 4 September 2019 Etikprövningsmyndigheten lämnar nu det ärendehanteringssystem som utvecklats i Prisma för etikprövningar. Anledningen är att det inte ger det stöd som var avsikten. Nu upphandlas istället ett nytt system och ambitionen är att det nya ska finnas på plats under 2020. Tills dess kommer myndigheten använda en övergångslösning för att hantera etikprövningar. Prisma stängs för

https://www.lupop.lu.se/article/etikprovningsmyndigheten-infor-nytt-arendehanteringssystem - 2025-01-10

Published 9 September 2019 Findings indicate that a very high percentage of patients coded with an MS diagnosis in the Swedish NPR actually have MS, and supports the use of the NPR as a viable source to identify individuals with an MS diagnosis for population-based research. Read more here.

https://www.lupop.lu.se/article/validation-multiple-sclerosis-diagnoses-swedish-national-patient-register - 2025-01-10

Published 9 September 2019 Participation in epidemiologic studies is steadily declining, which may result in selection bias. It is therefore an ongoing challenge to clarify the determinants of participation to judge possible selection effects and to derive measures to minimise that bias. We evaluated the potential for selection bias in a recent population-based cohort study with low baseline parti

https://www.lupop.lu.se/article/evaluating-selection-bias-population-based-cohort-study-low-baseline-participation-life-adult-study - 2025-01-10

Published 10 September 2019 Cerebral microbleeds (CMB) on MRI are frequent in healthy aging individuals but precede ischemic and hemorrhagic stroke and dementia. Different etiologies have been suggested for nonlobar CMB, which have a stronger connection to hypertension (HT) than do lobar CMB. This study aimed to investigate the prevalence of CMB and the association between nonlobar/lobar CMB and d

https://www.lupop.lu.se/article/association-between-cerebral-microbleeds-and-hypertension-swedish-general-population-good-aging - 2025-01-10

Published 11 September 2019 In their simulation study, Choi et al. compared different methods for handling missing covariate data in the context of propensity score analysis. This study addressed an important question on how propensity score matching and weighting perform coupled with different methods handing missing data when a treatment effect is homogenous or heterogeneous. New publication in

https://www.lupop.lu.se/article/validity-propensity-score-analysis-using-complete-cases-partially-observed-covariates - 2025-01-10

Published 12 September 2019 In thinking of the history of epidemiology, the map usually comes to mind before the calendar or the clock. During the nineteenth century, the study of the pattern and distribution of disease commonly suggested a terrain, a spatial ordering, that might align with environmental hazards, or later, with bacteriological threats. New publication in Internationa Journal of Ep

https://www.lupop.lu.se/article/history-epidemiology - 2025-01-10

Published 13 September 2019 The 1918 influenza pandemic had not only a massive instant death toll but also lasting effects on its survivors. Several studies have shown that children born in 1919, and thus exposed to the H1N1 virus in utero, experienced worse health and socioeconomic outcomes in older ages than surrounding birth cohorts. New publication in Demography.Read more here.

https://www.lupop.lu.se/article/long-lasting-influenza-impact-fetal-stress-during-1918-influenza-pandemic-socioeconomic-attainment - 2025-01-10

Published 10 September 2019 Du kommer tillhöra forskningsdatagruppen och ha ditt huvudsakliga arbetsområde inom verksamhetsområdet publicerings- och forskarstöd i biblioteket. Du kommer samverka med kollegor i biblioteket som arbetar med liknande frågor. Eftersom arbetsområdet är universitetsövergripande kommer du också att samarbeta med andra forskningsstödjande avdelningar inom förvaltningen och

https://www.lupop.lu.se/article/utredare-forskningsdata-vid-stockholms-universitetsbibliotek - 2025-01-10

Published 12 September 2019 Forskning har stor betydelse för samhällets utveckling och är också en omfattande sektor där ett flertal aktörer samverkar. Hur bör den svenska forskningspolitiken utformas för att stärka forskningen, bidra till att lösa dagens samhällsutmaningar och skapa ny kunskap för en klokare värld? Läs mer här.

https://www.lupop.lu.se/article/forskningspolitiska-dagen-2019 - 2025-01-10

Published 13 September 2019 Vetenskapsrådet har fattat beslut om vilka ansökningar som beviljats bidrag inom utlysningarna Bidrag till Forskningsmiljö inom registerbaserad forskning respektive Forskarskolor inom registerbaserad forskning 2019. Totalt har man beviljat 102 mkr för perioden 2020–2023, varav 13 mkr gick till lU-projektet "Användning av artificiell intelligens inom registerforskning (A

https://www.lupop.lu.se/article/vr-pengar-till-lu - 2025-01-10

Published 16 September 2019 It is a challenge to find participants for Alzheimer's disease (AD) prevention trials within a short period of time. The European Prevention of Alzheimer's Dementia Registry (EPAD) aims to facilitate recruitment by preselecting subjects from ongoing cohort studies. This article introduces this novel approach. New publication in Alzheimers Dement.Read more here.

https://www.lupop.lu.se/article/european-prevention-alzheimers-dementia-registry-recruitment-and-prescreening-approach-longitudinal - 2025-01-10

Published 17 September 2019 Drug-related problems due to medication errors are common and have the potential to cause harm. This study, which was conducted in Swedish primary health care, aimed to assess how well the medication lists in the medical records tally with the medications used by patients and to explore what type of medication errors are present. New publication in BMC Family Practice.R

https://www.lupop.lu.se/article/medication-errors-primary-health-care-records-cross-sectional-study-southern-sweden - 2025-01-10

Published 18 September 2019 In Japan, the are approximately 300 projects conducting research on rare deseases supported by the Ministry of Health, Labour and Welfare of Japan (MHLW) and the japan Agency for Medical Research and Development (AMED). Diverse data, including clinical, genomic, and sample-related data, are generated by these projects. New publication in wileyonlinelibrary.comRead more

https://www.lupop.lu.se/article/national-platform-rare-diseases-data-registry-japan - 2025-01-10

Published 19 September 2019 The occurrence of thyroid cancer is increasing throughout the developed world and since the 1990s has become the fastest increasing malignancy. In 2014, a total of 2693 Australians and 302 New Zealanders were diagnosed with thyroid cancer, with this number projected to rise to 3650 in 2018. The purpose of this protocol is to establish a binational population-based clini

https://www.lupop.lu.se/article/development-binational-thyroid-cancer-clinical-quality-registry-protocol-paper - 2025-01-10

Published 20 September 2019 The IMI DIRECT cohorts are intensely characterised, with a wide-variety of metabolically relevant measures assessed prospectively. We anticipate that the cohorts, made available through managed access, will provide a powerful resource for biomarker discovery, multivariate aetiological analyses and reclassification of patients for the prevention and treatment of type 2 d

https://www.lupop.lu.se/article/discovery-biomarkers-glycaemic-deterioration-and-after-onset-type-2-diabetes-descriptive - 2025-01-10