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Paleolithic Diet, Abdominal Adiposity, and Systemic Low-grade Chronic Inflammation. Associations in Observational Studies and a Randomized Controlled Trial

Background: Systemic low-grade chronic inflammation (SLGCI), commonly assessed by biomarkers such as total leukocyte count, neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP), is associated with cardiometabolic disease, and both are associated with diet and abdominal adiposity. The Paleolithic diet may reduce SLGCI by reducing abdominal adiposity and through direct effects on the i

Human Rights and Corporate Social Responsibility

The recently adopted Norwegian Transparency Act obliges companies under the scope of the law to safeguard human rights and decent working conditions in their respective supply chain and publish annually reports about their efforts. This legislation aligns with the current trend of Western governments to regulate Western companies’ business conduct in the global supply chain by transitioning from v

From Policy to Practice: Socio-Economic Challenges in Accessing Support Services for Students with Learning Difficulties in Greece - A Bourdieusian Analysis

While international research is increasingly concerned about the role of socio-economic status in special education, Greek scholars have focused on the psychological and behavioural aspects and their connection to academic attainment, overlooking the impact of socio-economic status. Even though the Greek legal framework advocates for inclusive education, there is a significant gap between policies

Straight from the Horse’s Mouth: A Socio-legal Analysis of the Philippine War on Drugs under President Rodrigo Duterte through Stanley Cohen’s States of Denial

This study examines the paradoxical public support for President Rodrigo Duterte's War on Drugs (WOD) in the Philippines (2016-2022) despite widespread evidence of human rights violations and extrajudicial killings (EJKs). Through a socio-legal lens and employing Stanley Cohen's "States of Denial" framework, this research analyzes how Duterte's public rhetoric justified, norm

Patient choice as a means of empowerment in opioid substitution treatment : a case from Sweden

Patient choice of treatment provider was introduced within opioid substitution treatment in the southern Swedish county of Skåne in 2014. Substitution treatment has often been criticised for being strict, rule-based, and driven by an ethos of discipline. This study explores the patients’ views and experiences of patient choice, particularly as a potential means of empowerment. The study is based o

Metabolic engineering of yeast for improved whole-cell biocatalytic amine production

Saccharomyces cerevisiae has emerged as a versatile platform for whole-cell biocatalysis, owing to its intrinsic regeneration of cofactors and amenability to genetic engineering. However, efficient reductive amination of aromatic carbonyls remains challenging due to competing redox pathways and product inhibition by pyruvate. Building on the redox-rewired TMB4133 strain (∆gpd1,2) that accumulates

Association of Osteopontin and selective glomerular hypofiltration syndrome with hospitalization for kidney failure in acute heart failure patients

BACKGROUND: Selective glomerular hypofiltration syndrome (SGHS), formerly shrunken pore syndrome, an emerging marker of glomerular dysfunction, is associated with worsened prognosis in cardiovascular disease, but its role in kidney failure remains underexplored. Osteopontin (OPN) is associated with worsening kidney function and prognosis in chronic kidney disease.PURPOSE: To explore if increased l

Janus kinase 1 inhibitors for treating immune checkpoint inhibitor-induced enterocolitis - report of two filgotinib-treated cases and literature review

BACKGROUND AND PURPOSE: Treatment of cancer with immune checkpoint inhibitors (ICIs) entails a risk of immune-related adverse events (irAEs). Data on the treatment of immune-related enterocolitis (irEC) in patients with inadequate symptom control after treatment with standard therapy including corticosteroids, infliximab, and vedolizumab are scarce. Based on limited data, recommendations include t

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The Öresund – the strait between eastern Denmark and southwestern Sweden – is an ancient focal point for trade, conflict, and cooperation in Northern Europe. The control of the strait has been of utmost strategic importance in Northern Europe over the centuries, involving several wars between Denmark and Sweden. During the 19th and 20th centuries, a decidedly more peaceful relationship developed b

Effects of Maternal Use of the Continuum of Care on Complementary Feeding Practices in Bangladesh: Cross-Sectional Study

Background: The continuum of care (CoC) for maternal health, which includes ≥4 antenatal care (ANC) visits, delivery assisted by skilled birth attendants, and a postnatal care (PNC) visit within 48 hours of delivery, is a crucial health care package associated with survival and improved health outcomes for children and mothers. In addition, the CoC serves as a platform for delivering messages and

The Onboarding Journey: From Attracting to Belonging A Thematic Literature Review Examining the Onboarding Process

Onboarding is a critical and strategically important process that significantly affects an organization's ability to attract, retain and engage new top talents in today’s competitive and rapidly evolving labor market. Despite a vast amount of research emphasizing the importance and benefits from having a structured onboarding process, many organizations continue to rely on outdated strategies

Generation, Self-assembly, and Characterisation of Medium-entropy Fe0.10Ni0.40Co0.25Pt0.25 Nanoparticles

The ongoing pursuit of advanced multicomponent magnetic nanomaterials with tailored functionalities for applications in data storage, spintronics, and biomedicine necessitates novel synthesis approaches beyond conventional template-based methods. In response, this thesis investigates the generation, self-assembly, and characterisation of largely little-known Fe0.10Ni0.40Co0.25Pt0.25 medium-entropy

Approaching 100Sn : Structural evolution in 98,100Cd via lifetime measurements

The lifetimes of low-lying excited states below the 8+ seniority isomer were directly measured using fast timing detectors in the neutron-deficient isotopes 98,100Cd. This experiment was conducted with the DEcay SPECtroscopy (DESPEC) setup at GSI, where the ions of interest were produced via a fragmentation reaction and identified using the FRagment Separator (FRS) before being implanted in the AI