Background: Blood transfusion has been associated with decreased long-term survival in cancer patients, possibly due to various immunological factors. We aimed to evaluate if perioperative transfusions decrease survival in patients who undergo resection for esophageal or gastric cancer and to identify factors associated with such events. Methods: A population-based cohort study was conducted based

There is an elevated presence of mercury (Hg) in the biosphere because of anthropogenic activities. The resulting damage to ecosystems and human health increases dramatically when microorganisms produce highly toxic methylmercury (MeHg). Total Hg (THg), MeHg and ancillary water chemistry were measured in two connected lakes, separated by a short stream stretch, before (1996, 1998 and 2003) and aft

Objective: The objective of this study was to assess the association between hip muscle strength and hip-related patient-reported outcome measures (PROMs) in patients with longstanding hip and groin pain (LHGP). Design: Cross-sectional design. Setting: Orthopedic care. Participants: Eighty-one patients with LHGP were consecutively recruited. Main outcome measures: Hip muscle strength was measured

We extend the notion of a spectral triple to that of a higher-order relative spectral triple, which accommodates several types of hypoelliptic differential operators on manifolds with boundary. The bounded transform of a higher-order relative spectral triple gives rise to a relative K-homology cycle. In the case of an elliptic differential operator on a compact smooth manifold with boundary, we ca

This paper presents a topology optimization framework utilizing a deformation plasticity model to approximate the isotropic hardening von-Mises incremental elastoplasticity model under monotone proportional loading. One advantage of the model is that it is based on a yield surface allowing for precise matching to uniaxial elastoplastic isotropic hardening response. The deformation plasticity model

Thomas Hood’s poem “The Song of the Shirt” was an immediate success when first published in Punch in 1843. Previous research has shown how the poem responded to the mid-nineteenth-century debate concerning the working situation of needlewomen. The ways in which this hugely popular poem was recontextualised in translation have, however, received surprisingly little attention. Arguing that British nThomas Hood’s poem “The Song of the Shirt” was an immediate success when first published in Punch in 1843. Previous research has shown how the poem responded to the mid-nineteenth-century debate concerning the working situation of needlewomen. The ways in which this hugely popular poem was recontextualised in translation have, however, received surprisingly little attention. Arguing that British n

Transactional sexual relationships (TSRs) take varied forms, with research emphasizing TSRs’ inherent risks, primarily to women. In South Africa, Blessed relationships have emerged as a prominent type of TSR. Blessers have become coveted male partners due to their relative wealth and willingness to ‘bless’ female partners with financial and material gifts, as well as the improved social status tha

Background: Maternally-inherited symbionts can induce pre-mating and/or post-mating reproductive isolation between sympatric host lineages, and speciation, by modifying host reproductive phenotypes. The large parasitoid wasp genus Cotesia (Braconidae) includes a diversity of cryptic species, each specialized in parasitizing one to few related Lepidoptera host species. Here, we characterized the in

By measuring X-ray emission of the water molecule in liquid phase we establish a first example of K-shell X-ray emission spectra with strong breakdown of the molecular orbital picture. A complete splitting of the 2a1 peak into satellites is observed. A theoretical model with electronic configurations generated by coupled excitations/de-excitations, so-called semi-internal configuration interaction

Background: Platelet transfusions are given to preterm infants with severe thrombocytopenia aiming to prevent haemorrhage. The PlaNeT2/MATISSE trial revealed higher rates of mortality and/or major bleeding in preterm infants receiving prophylactic platelet transfusions at a platelet count threshold of 50 × 109/L compared to 25 × 109/L. The extent to which this evidence has been incorporated into c

Poverty is prevalent among rural smallholder farmers in low-income countries. A large body of literature suggests that contract farming can improve smallholder’s welfare through improved market access and promote rural development. Existing studies usually focus on single welfare components and concentrate on a single crop, contract scheme, or geographical area, and 'big picture' analyses remain s

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Background: Tuberous sclerosis (TSC) is a rare genetic disorder associated with a high prevalence of drug-resistant epilepsy (DRE), for which epilepsy surgery may be a viable therapeutic option. National prospective studies with long-term follow-up (LTFU) and the identification of outcome predictors are needed.Methods: Individuals with TSC but no history of previous epilepsy surgery were identifie