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Investment in immune defense is linked to pace of life in house sparrows
The evidence for a relationship between life history and immune defense is equivocal, although the basic premise is intuitively appealing: animals that live short lives and reproduce early and rapidly should not waste resources on defenses they might never use. One possible reason for a lack of strong support for this hypothesis could be the inherent complexity of the vertebrate immune system. Ind
Role of N-linked glycans on bunyamwera virus glycoproteins in intracellular trafficking, protein folding, and virus infectivity.
The membrane glycoproteins (Gn and Gc) of Bunyamwera virus (BUN, family Bunyaviridae) contain three potential sites for the attachment of N-linked glycans: one site (N60) on Gn and two (N624 and N1169) on Gc. We determined that all three sites are glycosylated. Digestion of the glycoproteins with endo-beta-N-acetylglucosaminidase H (endo H) or peptide:N-glycosidase F revealed that Gn and Gc differ
Separation of amino acids, peptides and proteins on molecularly imprinted stationary phases.
Stationary phases, to be used in high-performance liquid chromatography, were tailor-made for the separation of amino acids, peptides and proteins. The stationary phases were prepared by molecular imprinting, applying two different approaches. Low-molecular-mass compounds were imprinted in bulk polymers by copolymerization of functional monomers and cross-linkers in the presence of the compound of
P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells.
Occupational Perspectives on Health in People with Schizophrenia
Popular Abstract in Swedish Denna avhandling har bidragit med systematisk information om hur personer med schizofreni lever sitt vardagsliv, och resultaten har visat på signifikanta relationer mellan ett aktivitetsperspektiv och hälsa. Avhandlingen består av fem studier. De första två är kvalitativa studier som handlar om tidsanvänding i förhållande till aktivitetsutförandet och aktivitetsengagemaThe thesis has provided with systematic information about how people with schizophrenia live their everyday life, and the results have shown significant relationships between occupational perspectives and health. The thesis departed in two in-depth studies that concerned time use and occupational engagement in relation to what people with schizophrenia do in their everyday life, with whom they are
Indications of improved cognitive development at one year of age among infants born very prematurely who received care based on the Newborn Individualized Developmental Care and Assessment Program (NIDCAP)
Background and Objective: Care based on the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) has been reported to exert a positive impact on the development of prematurely born infants. The aim of the present investigation was to determine the effect of such care on the 1-year development of infants born with a gestational age of less than 32 weeks. Methods: All surviving
Observation of fusion-like residues in energetic nuclear collisions at the Celsius storage ring
Recent experiments at the CELSIUS storage ring of Uppsala, Sweden, have revealed the existence of high momentum transfer target-like fragments contrary to expectations. Recoiling heavy fragments in the reaction of 250 MCV/nucleon N-14 on Xe-131 have been measured at 10degrees with respect to the beam direction with specially designed recoil telescopes, Simulations with the Boltzmann-Uehling-Uhlenb
Life and work during 5,000 years
The Wind-Water Tunnel at IMES - A Facility for Empirical Studies of Aerosol Deposition
Degradation of toxaphene in water during anaerobic and aerobic conditions
The degradation of technical toxaphene in water with two kinds of bioreactors operating in sequence was studied. One packed bed reactor was filled with Poraver(R) (foam glass particles) running at anaerobic conditions and one suspended carrier biofilm reactor working aerobically. Chemical oxygen demand (COD), chloride, sulphate, pH, dissolved oxygen, total toxaphene and specific toxaphene isomers
Species composition and population fluctuations of alpine bird communities during 38 years in the Scandinavian mountain range
Markets are more than Bits
This paper argues that the main contribution of Mirowski's paper is the new combination of some seemingly unrelated ideas, like principles for market evolvement and automata theory. Furthermore, many of Mirowski's ideas ought to be inspiring for future economic research. However, it is argued that some ideas, if scrutinized, are difficult to motivate, and other need further refinement before they
Nerve regeneration enhancement by tourniquet
The use of tourniquet compression as a non-invasive method to enhance axonal regeneration was assessed in the rat sciatic nerve. One hind limb of the rat was subjected to compression by a tourniquet set at 300 mmHg for 30 or 120 min followed by bilateral test crush lesions performed either directly or after a conditioning interval of 3 or 6 days, with the non-compressed side serving as a control.
Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin
Secretagogin is a hexa EF-hand protein, which has been identified as a novel potential tumour marker. In the present study, we show that secretagogin binds four Ca2+ ions (log K-1 = 7.1 +/- 0.4, log K-2 = 4.7 +/- 0.6, log K-3 = 3.6 +/- 0.7 and log K-4 = 4.6 +/- 0.6 in physiological salt buffers) with a [Ca2+](0.5) of approx. 25 mu M. The tertiary structure of secretagogin changes significantly upo
Operation of the ATLAS Transition Radiation Tracker under very high irradiation at the CERN LHC
The ATLAS Transition Radiation Tracker (TRT) performance depends critically on the choice of the active gas and on its properties. The most important operational aspects, which have led to the final choice of the active gas for the operation of the TRT at the LHC design luminosity, are presented. The TRT performance expected at these conditions is reviewed, including pile-up effects at high lumino
Immunolocalization of cholecystokinin-2 receptors in rat gastric mucosa
Background: Gastrin exerts trophic effects on the gastric mucosa by mechanisms not yet completely elucidated. Our aim was to localize the cholecystokinin-2 (CCK2) receptor in epithelial cells of foetal and adult rat stomachs in order to determine the cell types that are directly affected by gastrin. Methods: Gastric tissue was subjected to indirect double immunofluorescence staining with antiserum
New methods for improved evaluation of patients with suspected acute coronary syndrome in the emergency department
This paper aims to identify and review new and unproven emergency department (ED) methods for improved evaluation in cases of suspected acute coronary syndrome (ACS). Systematic news coverage through PubMed from 2000 to 2006 identified papers on new methods for ED assessment of patients with suspected ACS. Articles found described decision support models, new ECG methods, new biomarkers and point-
Macroeconomic variables and corporate performance
Increased economic and financial integration and substantial macroeconomic fluctuations require that corporate managers and investment analysts pay more attention than in the past to the link between the "noise" that these fluctuations represent and the company's performance-past and future. For many reasons, company managers must weed out the effects of the noise to obtain a clear picture of the