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1. The mechanisms by which cooling inhibits insulin secretion were investigated by capacitance measurements of exocytosis in single mouse pancreatic B-cells maintained in short-term tissue culture. 2. A reduction of the bath temperature from 34 to 24 degrees C produced a gradual inhibition of exocytosis. Inhibition of exocytosis was use dependent rather than time dependent. The steady-state inhibi

Popular Abstract in Swedish I avhandlingen presenteras ett matematiskt ramverk för analys av datagenomströmning i paket-baserade radionät som stör varandra. Tidigare forskning om prestanda i paketradionät täcker många olika system och aspekter. Tidigare publicerade arbeten har dock till stor del varit begränsade till fixa paketlängder. Ramverket som presenteras i avhandlingen tillåter detaljerad aIn this thesis, a probabilistic framework is presented and used for analysis of the throughput of interfering packet-based radio networks, referred to as packet radio networks (PRNs). Previous research on the performance of PRNs covers a wide variety of systems and aspects in varying levels of detail. However, the work presented in the literature has mostly been limited to fixed packet lengths. Th

The dissertation is a case study, the topic of which was a participant-oriented research project in which a development programme for support to parents and care of young people was to be implemented in the organization and the concrete social work was developed and changed through researcher-supported intervention. The project was part of a large-scale effort for change and development carried ou

CASCADE is a full hadron level Monte Carlo event generator for ep, gammap and p (p) over bar processes, which uses the CCFM evolution equation for the initial state cascade in a backward evolution approach supplemented with off-shell matrix elements for die hard scattering. A detailed program description is given, with emphasis on parameters the user wants to change and common block variables whic

Formation of germ tubes by Candida albicans has been assumed as a putative virulence factor. Local anesthetics (LAs), e.g., lidocaine and bupivacaine, are known to inhibit germ tube formation. The study confirmed this observation for the novel drug ropivacaine, although it was less potent than the former two drugs. Hypothesizing that the effect is due to blockading ionic channels, we exposed Candi

This thesis is based on four papers (A-D) treating filtering, smoothing, and maximum likelihood (ML) estimation in general state space models using stochastic particle filters (also referred to as sequential Monte Carlo (SMC) methods). The aim of Paper A is to study the bias of Monte Carlo integration estimates produced by the so-called bootstrap particle filter. A bound on this bias which is inv

High-resolution palynofloral signatures through the Cretaceous-Palaeogene boundary succession show several features in common with the Permian-Triassic transition but there are also important differences. Southern Hemisphere Cretaceous-Palaeogene successions, to date studied at high resolution only in New Zealand, reveal a diverse palynoflora abruptly replaced by fungi-dominated assemblages that a

A systematic spectroscopic study of single ZnWO4 :Fe crystals with different iron concentrations has been performed under excitation by ultraviolet light, by synchrotron radiation or under photostimulation by near-infrared light. The luminescence of Fe3+-related centres has been studied. It is shown that iron centres of different types efficiently promote the formation of crystal defects at low te

Strategies for the preparation of multinuclear complexes containing homoditopic and heteroditopic ligands based upon 2,2$-bipyridine (bpy) and 2,2:6$,2$$-terpyridine metal binding domains are presented. Both conventional approaches based upon preparation of a free ligand and subsequent coordination and metal-directed reactions of coordinated ligands are utilized in the various strategies. A repres

Objective. To evaluate the Cockcroft - Gault (CG) equation, using various body weight expressions, and the Sawyer equation in predicting glomerular filtration rate (GFR) using an enzymatic and zero-calibrated Jaffe plasma-creatinine assay, and to derive a new robust equation in adults. Material and methods. The CG weight measures included total, ideal and adjusted body weight (ABW; lowest of total

Ultra-fast time-delayed techniques have been recently applied in a number of studies where exotic nuclei were identified using advanced selection techniques. These include large Compton-suppressed Ge arrays, in-flight separators or recoil separators. Some of the new results are discussed in this presentation. Besides the results for Mg-32 and Pd-96, they include the first determination of the half

This report summarises the first phase of the project “Economic optimization of the industrial fire protection”. Results from the initial phase, along with suggestions for further research are presented.

Childhood asthma and wheeze is more common among boys than girls, white the opposite is found in adults. The main objective was to study the incidence and the course of wheeze and asthma during adolescence with focus on gender differences. In addition, we explored associations between lifestyle factors at baseline and wheeze at follow-up. A total of 2399 adolescents answered validated questionnair

Proteoglycans are well-known modulators of intercellular communication and signaling. Remodeling of the proteoglycans in the human uterus occurs throughout pregnancy, and during labor. We therefore hypothesize that heparan sulfate proteoglycans (HSPGs) play an important role in establishing normal labor. In this study HSPGs were characterized and localized in human uterine tissue. Uterine biopsies