Introduction: Risk factors of traditional substance use related problems in young adults are more well-known than for behavioral addictions such as gambling and gaming problems. The present study aims to provide knowledge about the longitudinal patters of substance use related and behavioral addictions in early adulthood. Methods: Using self-report surveys, substance-related, psychiatric, and demo

Huntington’s disease (HD) is caused by CAG repeat expansion in the huntingtin (HTT) gene. Skeletal muscle wasting alongside central pathology is a well-recognized phenomenon seen in patients with HD and HD mouse models. HD muscle atrophy progresses with disease and affects prognosis and quality of life. Satellite cells, progenitors of mature skeletal muscle fibers, are essential for proliferation,

Two unique Pre-Viking Age ship burials were found from Salme village, Saaremaa Island, eastern Baltic Sea, containing remains of seven men in the smaller and 34 men in the larger ship. According to the archaeological interpretations, these ships belonged to a viking crew possibly from the Stockholm-Mälaren region, eastern Sweden. Geoarchaeological research was conducted in the area to reconstruct

We experimentally investigate the properties of one-dimensional quantum rings that form near the surface of nanowire quantum dots. In agreement with theoretical predictions, we observe the appearance of forbidden gaps in the evolution of states in a magnetic field as the symmetry of a quantum ring is reduced. For a twofold symmetry, our experiments confirm that orbital states are grouped pairwise.

The goal of paleoproteomics is to characterize proteins from specimens that have been subjected to the degrading and obscuring effects of time, thus obtaining biological information about tissues or organisms both unobservable in the present and unobtainable through morphological study. Although the description of sequences from Tyrannosaurus rex and Brachylophosaurus canadensis suggested that pro

Public acceptability is important for sustainable land use zoning policy to be successfully implemented. This study examined the effectiveness of tailoring messages with cultural worldviews to induce positive attitudes and improve public acceptability of sustainable land use zoning policy in a post-conflict setting. A total of 538 participants were randomly divided into three groups. Two were trea

In 2018, NATO carried out Trident Juncture, its largest military exercise since the Cold War. The event was promoted on social media featuring Lasse Matberg as “the face of NATO”. Matberg is an Instagram influencer, model and lieutenant in the Royal Norwegian Navy, with an impressive physique and Viking looks. He frequently appears on NATOs social media accounts and lends his own platform to share

The Swedish government is at present investing heavily in making Sweden competitive in AI (Artificial Intelligence). As a part of that effort, Lund University has been commissioned with providing a series of MOOCs (Massive Open Online Courses) on different topics regarding AI, including several topics dealing with Humans and AI. As a comprehensive university, Lund University has an advantage in be

Background and purpose - Vitamin E infused highly cross-linked polyethylene (VEPE) was introduced in order to enhance oxidative resistance in highly cross-linked polyethylene cups in total hip arthroplasty (THA). We have, with a follow-up of 5 years, evaluated wear characteristics of 2 identically designed cemented cups with the only difference being the material, VEPE or ultra-high molecular weig

Background: Symptomatic osteoarthritis of the basal joint of the thumb (trapeziometacarpal joint) is a common disabling condition mainly affecting women. It is frequently treated with complete removal of the trapezium with or without soft-tissue interposition. There is limited evidence about whether removal of the trapezium affects stability of the wrist joint and increases the risk of developing

There is a great need to find cheaper but still efficient treatment methods for wastewater. This study aimed to test the purifying performance of three different Moringa oleifera varieties that were cultivated in Tunisia on raw (RUW) and secondary treated urban wastewater (TUW). The seeds of the Mornag, Egyptian, and Indian varieties were powdered, added to the water (at concentrations of 0, 50, 1

Hazardous materials encountered during building renovation or demolition processes not only result in uncertainty in cost estimation and the lead time but also hampers material recyclability and reuse. Therefore, the paper discusses the possibility of predicting the extent of the hazardous materials, including asbestos, PCB, mercury, and CFC, through data mining techniques based on registered reco

Introduction: The development of inhibitory antibodies is a severe complication of clotting factor replacement therapy in patients with severe haemophilia A (HA). Current World Federation of Hemophilia (WFH) guidelines for haemophilia care indicate that eradication of inhibitors is best achieved through immune tolerance induction (ITI) therapy. Aim: The European Collaborative Haemophilia Network c

Introduction Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease. Intra-articular stem cell therapy is increasingly being used for treating KOA with little high-quality evidence to support its use. The aim of this study is to investigate the efficacy, safety and cost-effectiveness of allogeneic mesenchymal stem cells (Cymerus MSCs) for treating symptomatic tibiofemoral KOA and

In patients with ST-segment elevation myocardial infarction (STEMI), ischemic postconditioning (iPOST) have shown ambiguous results in minimizing reperfusion injury. Previous findings show beneficial effects of iPOST in patients with STEMI treated without thrombectomy. However, it remains unknown whether the cardioprotective effect of iPOST in these patients persist on long term. In the current st

During embryonic development, hematopoiesis occurs through primitive and definitive waves, giving rise to distinct blood lineages. Hematopoietic stem cells (HSCs) emerge from hemogenic endothelial (HE) cells, through endothelial-to-hematopoietic transition (EHT). In the adult, HSC quiescence, maintenance, and differentiation are closely linked to changes in metabolism. However, metabolic processes