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Effect of divalent cations on pore formation and degradation of poly(D,L-lactide-co-glycolide).

Poly(D,L-lactide-co-glycolide) (PLG) is probably the biodegradable polymer most often used for polymeric controlled-release formulations. Different salts have been shown to affect the swelling and degradation of PLG, which, in turn, affect the release of encapsulated drugs. In this investigation the effect of divalent cations was especially investigated. Films of PLG were incubated in phosphate bu

Two Sides of the Same Coin: Bootstrapping the Restricted vs. Unrestricted Model

The properties of the bootstrap test for restrictions are studied in two versions: 1) bootstrapping under the null hypothesis, restricted, and 2) bootstrapping under the alternative hypothesis, unrestricted. This article demonstrates the equivalence of these two methods, and illustrates the small sample properties of the Wald test for testing Granger-Causality in a stable stationary VAR system by

Mechanical integrity of TCO films för flexible polymer-based displays

The mechanical integrity of tin-doped indium oxide (ITO) thin films sputtered onto a high temperature aromatic polyester developed for flexible display applications was investigated by means of tensile experiments equipped with electrical measurement, and carried out in-situ in an optical microscope. Attention was paid to the influence of ITO thickness, composition and crystalline microstructure,

Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources

Acquired chromosome abnormalities in tumours often reflect pathogenetic events at the gene level. Multicolour fluorescence in situ hybridisation (FISH) with single-copy probes offers extensive possibilities to characterise chromosome breakpoints in relation to the physical map of the human genome. This approach is based on the construction of comprehensive EST- based maps, combinatorial labelling

Intestinal Bypass and Total Parenteral Nutrition: Changes in Gut Function and Morphology

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Ett gott mål mat (enteral nutrition) och en välfungerande mag-tarmkanal från mun till brunn är för de flesta en självklarhet men för vissa mer en önskvärdhet. Vid sjukdom i tarm eller bukhåla kan det hända att ett tarmavsnitt nödga's koppla's ur den normala kontinuiteten genom anläggande av en så kallad stomi. Vid överviktskirurgi (exAbolition of enteral nutrition is sometimes required in severe illness. The primary aim of the present work has been to elucidate possible changes in intestinal morphology and motor function in absence of enteral nutrition. Total absence of enteral nutrition in an isolated intestinal segment was created by bypassing the distal ileum in a rat model. Intestinal bypass causes marked circumferential a

Quality of life after cystectomy and urinary diversion: An evidence based analysis

Purpose: We critically examined the evidence supporting the widely accepted notion that patients undergoing continent urinary tract reconstruction after cystectomy experience superior quality of life outcomes than patients receiving a conduit. Materials and Methods: Based on a comprehensive MEDLINE literature search we retrieved and evaluated all full-length articles published in the English, Fren

In-situ studies of the formation mechanism of SBA-15

The formation process of SBA-15 has been investigated by time resolved TEM, in-situ SAXS/SAXD and in-situ NMR. The synthesis was done at 35 degrees in acidic solution with tetramethylorthosilicate as the silica source and Pluronic P123 as the structure directing amphiphile. The initially formed silica-polymer composite consists of flocs of spherical micelles in a silica matrix. The micelles then c

alpha1-Antitrypsin regulates CD14 expression and soluble CD14 levels in human monocytes in vitro.

The recognition of bacterial lipopolysaccharide (LPS) is principally mediated by either membrane-bound or soluble form of the glycoprotein CD14 and CD14-associated signal transducer, toll-like receptor 4 (TLR4). Recent findings indicate that the serine protease inhibitor, alpha 1-antitrypsin (AAT), may not only afford protection against proteolytic injury, but may also neutralize microbial activit

Skola utan timplan - om lärares tolkning av uppdraget i en mål- och resultatstyrd skola

The issue of this article is the direction of the Swedish compulsory school. The article is based upon the results of a longitudinal study of four schools participating in a probation, initiated by the Swedish government, where they are allowed to work without the timetable. What regulates school activity when there is no timetable that prescribes the amount of time for each subject? What are the

Om återbruk och förfall

Sommaren är loppmarknadernas tid. I trakten där jag bor är det vanligt med någon loppmarknad varje helg. Det är stora tillställningar där den arrangerande idrotts- eller hembygdsföreningen under ett år har samlat in begagnade grejer som säljs till mycket låga priser. För många föreningar är vinsten från försäljningen en viktig post i budgeten. Poängen med loppmarknaden är att föremål som i någons

Passion Embracing Death : A reading of Nina Sadur's novel 'The Garden'

Popular Abstract in Swedish Avhandlingen analyserar romanen "Lustgården" av den ryska författaren Nina Sadur (på ryska 1997, på svenska 2001). Feministisk litteraturteori används för att problematisera receptionen av Sadurs verk samt för att motivera valet av verk för analys. Avhandlingen är indelad i två delar: Del ett presenterar en linjär läsning av romanen, där den läses som ”avikande diskursThis doctoral dissertation is an analysis of the novel 'The Garden' (1997), by the Russian author Nina Sadur. Drawing on feminist literary criticism, it aims at providing a woman-authored text with the in-depth study the novel’s literary sophistication calls for. The dissertation is divided into two parts: Part One presents a linear reading of the novel in which it is read as ‘aberrant discourse’

Robust Control under Parametric Uncertainty via Primal-Dual Convex Analysis

A numerical synthesis method for optimally robust control isproposed. The method applies to the case of linear dependenceon uncertain parameters in the characteristic polynomial. Aprimal/dual pair of infinite-dimensional convex problems is solvedby successive finite-dimensional approximations. The primal/dualpair has no duality gap, and both upper and lower bounds produced by theapproximations con

Stated preference methods and empirical analyses of equity in health economics

This dissertation considers two different aspects of health economics; (i) stated preference methods and (ii) empirical analyses of equity. The first essay deals with the issue of the choice of econometric models when analysing data from a closed-ended contingent valuation survey in health economics. The features of provision, either compulsory or voluntary, and the fact that certain individuals m