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The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register systematically all published cytogenetic aberrations reported in cancer, including patient and tumor characteristics, gene fusions identified by cytogenetics or massively parallel sequencing, and studies pertaining to the clinical relevance of cytogenetic aberrations and/or gene rearra

https://www.clinicalgenetics.lu.se/division-clinical-genetics/database-chromosome-aberrations-and-gene-fusions-cancer - 2025-12-19

  Soft tissue tumors (STT) constitute a heterogeneous group of approximately 100 distinct neoplasms, including more than 50 malignant subtypes, so-called sarcomas. Genetic analyses have shown that the clinical and biological variation among these neoplasms is reflected in their genotypes. While the diagnosis of STT has been improved by such genetic biomarkers, the use of genetic information for im

https://www.clinicalgenetics.lu.se/division-clinical-genetics/genetics-soft-tissue-tumors - 2025-12-19

The goal of our research is to increase our understanding of the leukemogenic process and to investigate the clinical impact of genetic/epigenetic abnormalities in pediatric acute lymphoblastic and myeloid leukemia. In order to achieve this goal, we use several types of “next generation sequencing”, such as whole genome sequencing, whole exome sequencing, and RNA sequencing, and various methylatio

https://www.clinicalgenetics.lu.se/division-clinical-genetics/geneticsepigenetics-pediatric-leukemia - 2025-12-19

   Gains and losses of whole chromosomes, termed aneuploidy, is seen in at least half of all tumors. How it affects tumorigenesis is still poorly understood. We use hyperdiploid (51-67 chromosomes) pediatric acute lymphoblastic leukemia (ALL) as a model to study aneuploidy, focusing on:How does the cell become aneuploid? We use large-scale sequencing and array-based analyses of bulk and single cel

https://www.clinicalgenetics.lu.se/division-clinical-genetics/aneuploidy-cancer - 2025-12-19

The highly complex genome of an osteosarcoma.Our aim is to develop new treatment strategies for patients with highly aggressive malignancies. To this end, we screen clinical tumor material for disease-causing mutations using deep sequencing technology and we manipulate genes of interest in cancer model systems to understand the true consequences of mutations.Most high-grade cancers harbor mutation

https://www.clinicalgenetics.lu.se/division-clinical-genetics/complex-genomes-cancer - 2025-12-19

https://www.clinicalgenetics.lu.se/department-clinical-genetics - 2025-12-19

Aneuploidy in Cancer Kajsa Paulsson - We aim to understand how aneuploidy - changes in the number of chromosomes – arises and affects cancer cells.  The Molecular Pathogenesis of Leukemia Anna Hagström- We aim to understand the mechanisms involved in hematopoietic cell transformation using a combination of genomic approaches and leukemia mouse models. Cancer Cell Evolution David Gisselsson Nord -

https://www.clinicalgenetics.lu.se/division-clinical-genetics - 2025-12-19

The Clinical Coagulation Research Unit at Lund University is a part of Malmö Center for Thrombosis and Haemostasis, which is a highly specialized centre for bleeding and thrombotic disorders within Region Skåne. The Center is unique in that it combines clinical and laboratory know-how. This highly specilized centre is a national centre for the investigation of patents with bleeding and thrombotic

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit - 2025-12-19

An international, case-oriented course for physicians in need of further education in von Willebrand disease Date: TBDLocation: TBDApplication: TBD 

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/education/von-willebrand - 2025-12-19

Theses at the Clinical Coagulation Research Unit from 1997 to presentThe links lead to Lund University's Research Information System (LUCRIS) if nothing else is stated. Alexandros Arvanitakis (2024-05-03): Haemophilia A - In pursuit of optimised outcomes via personalised treatment (supervisor: Jan Astermark/Nadine Gretenkort Andersson, assistant supervisor: Erik Berntorp)Raein Ghazvinian (2023-06-

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/theses - 2025-12-19

Our international hemophilia courses/workshops International course in hemophilia - from basic to advancedDate: 8-10 October, 2024Location: High Court, Malmö, SwedenThis is an international, case-oriented course for physicians in need of further training in hemophilia.The aim of this course is to summarize and highlight the current state-of-the-art management of patients with a focus on personaliz

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/education/hemophilia - 2025-12-19

Team members of the Clinical Coagulation Research Unit Jan AstermarkProfessorEmail: jan [dot] astermark [at] med [dot] lu [dot] se (jan[dot]astermark[at]med[dot]lu[dot]se)Jan Astermark's profile in Lund University research portal (LUCRIS)  Erik BerntorpSenior professorEmail: erik [dot] berntorp [at] med [dot] lu [dot] seErik Berntorp's profile in Lund University research portal (LUCRIS) Peter Sven

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/team - 2025-12-19

PhD students belonging to the Clinical Coagulation Research Unit

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/phd-students - 2025-12-19

We have annually for 25 years given a course under the direction of the National Board of Health and Welfare for prospective specialists in various areas of coagulation. The main areas of the course are basic understanding of coagulation and case discussions of bleeding and thromboembolic conditions. Application through the National Board of Health and Welfare [page in Swedish].11-15 November, 202

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/education/state-funded-courses-doctors-during-specialization-sk-kurser - 2025-12-19

Within the coagulation unit, several research projects are underway in both the thrombosis and the bleeding area. Thrombosis research includes epidemiological studies of coagulation disorders and research on various forms and combinations of anticoagulant treatment.Bleeding disordersIn the bleeding area, there are projects related to hemophilia, von Willebrand's disease (VWD), platelet function di

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/research-projects - 2025-12-19

Courses in the area of thrombotic and bleeding disorders provided by the Clinical Coagulation Research Unit HemophiliaVon WillebrandState-funded courses for doctors during specialization (SK-kurser) 

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/education - 2025-12-19

International, Nordic and Swedish guidelines for bleeding and thrombotic disorders Bleeding and thrombotic disordersGuidelines - bleeding, thrombotic and thrombophilia disorders (SSTH, external page, Swedish)Guidelines - NOAC and hemophilia (department of hematology, Region Skåne, external page, Swedish)NOACs and atrial fibrillationBackground NOACs (Swedish Medical Products Agency 2017: NOAK: Fakt

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/guidelines - 2025-12-19

Links to external international, Nordic and Swedish web pages on bleeding and thrombotic disorders American Society of Hematology (ASH)Aroseniusfonden (Arosenius fund)British Society for Haematology (BSH)Department of Clinical Chemistry and Pharmacology (Coagulation laboratory)Department of Translational Medicine, Lund UniversityEuropean Hematology Association (EHA)International Society on Thrombo

https://www.clinical-coagulation.lu.se/welcome-clinical-coagulation-research-unit/links - 2025-12-19

Vetenskapliga tidskrifter (peer-reviewed) Whitman, M.G., K. Barker, J. Johansson, and M. Darayi. (2017). Component Importance Measures for Multi-Commodity Networks: Application in Swedish Railway. Computers and Industrial Engineering, No. 112, pp. 274-288. https://doi.org/10.1016/j.cie.2017.08.004 Vetenskapliga konferenser (peer-reviewed) Hassel, H. & Cedergren A. (2017). A method for combined ris

https://www.cencip.lu.se/publikationer/forskningspublikationer-inom-cencip/2017-forskningspublikationer - 2025-12-19

Svenska konferenser/seminarierRisk to critical infrastructures and technical systems, Presentation av Henrik Tehler, Lunds universitets 350-års jubileum. Länk till film.

https://www.cencip.lu.se/publikationer/presentationer/2017 - 2025-12-19