Adherence to maintenance therapy is often poor in patients with asthma. Simplifying dosing regimens has the potential to improve both adherence and asthma-retated morbidity. In this 12-week, randomized, double-blind, double-dummy, parattel-group study, 617 patients with mild to moderate persistent asthma (mean forced expiratory volume in 1 s [FEV,] 78.5% predicted) who were not optimally controlle

Popular Abstract in Swedish Kritiskt sjuka patienter på intensivvårdsavdelningar (IVA) har ofta störningar i blodets levringsförmåga (koagulation). Kliniska tecken som blodpropp (djup ventrombos eller blodpropp i lungorna) och/eller blödning kan vara resultatet av aktivering och konsumtion av koagulationsfaktorer och koagulationshämmare. Disseminerad intravaskulär koagulation (DIC, som är en samtiCritically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma

Variability in cover of five field layer species was recorded during ten consecutive years in thirty permanent plots within a south Swedish Carpinus betulus forest. The studied species were Oxalis acetosella, Lamium galeobdolon, Stellaria holostea, Hedera helix and Holcus mollis. We observed great interannual variability in cover percentage of all studied species with 76% out of all year-to-year d

The anthology Möten och metamorfoser ("Meetings and metamorphoses")consists of intermedial and interartial analyses.

We have demonstrated in sensitized rats that the immediate response to endointestinal challenge with allergen (10(-6) M ovalbumin) is characterized by mucosal exudation of plasma with little or no concomitant change in the mucosal absorption capacity. The luminal entry of plasma macromolecules also leaves the light microscopic structure and the ultrastructure of the mucosa unaffected. It is possib

The complete genome sequences of cyanobacteria and of the higher plant Arabidopsis thaliana leave no doubt that the plant chloroplast originated, through endosymbiosis, from a cyanobacterium. But the genomic legacy of cyanobacterial ancestry extends far beyond the chloroplast itself, and persists in organisms that have lost chloroplasts completely.

Anti-leukotriene therapy represents a new principle in asthma treatment. As elite athletes can have asthma, this double-blind, placebo-controlled, randomised cross-over study investigated the effect of 10 mg oral montelukast, a specific and potent cysteinyl leukotriene receptor antagonist, on physiological responses to submaximal and maximal aerobic exercise at -15 degrees C in 14 non-asthmatic hi

As an extension of previous studies on modeling and identification of nonlinear dynamic load models, this letter describes the influence of the normalization in dynamic reactive load models. Using measured data from normal operation, it is shown that the reactive power level, which has previously used as normalization factor is inappropriate. If instead apparent power level is used, the variabilit

No abstract available

In later years the development of pavement design has gone towards more and more analytically based methods. Future design will probably be based on incremental deterioration models. The objective is to evaluate different types of rut depth prediction models for an incremental design process. Two different models were chosen for further studies: One model that calculates the plastic strain throu

The experience with radioimmunotherapy in B-cell lymphomas using the rapidly internalizing antibody, anti-CD22 (LL2), is limited. In this study we investigated the efficacy and toxicity of 131I-labelled-LL2 for radioimmunotherapy in patients with B-cell lymphomas that failed one or two cytostatic regimens. Eleven patients were treated with one or repeated cycles of 131I-anti-CD22 antibody, 1330 MB

Platelet activating factor (PAF) has been reported to produce a variety of airway effects including epithelial damage and increased airway-lung absorption of hydrophilic tracers. The present study examines effects of PAF on the guinea-pig tracheobronchial mucosa in vivo. Vehicle with and without PAF (4.0 and 8.0 nmol) was superfused onto the tracheobronchial mucosa. The levels of 125I-albumin, pre

Studien analyserar möjligheterna att reducera energianvändning och emissioner från den svenska transportsektorn fram till år 2015. Energianvändning och emissioner beräknas utifrån officiella prognoser om transportarbetets utveckling samt uppskattningar av specifik energianvändning och emissionsfaktorer för olika teknologi- och bränsleval och transportslag. Emissionerna jämförs med såväl officiell

The new paramyxean Paramyxoides nephtys gen. n., sp. n. is described based on cytological characters. The organism reproduces by endogenous budding, and sporogony is the only sequence of reproduction observed. A primary cell with narrow haplosporosomes gives rise to two or four secondary cells (sporonts), each yielding four tetracellular spores in which the cells are situated one within the other.

Rapport från en internationell konferens i Montreal 11-13 oktober 1998 "The First International Conference on New Information Technologies for Decision Making in Civil Engineering". Författaren (som är bibliotekarie) var den enda representanten från Sverige bland ca 280 forskare från 26 länder, och berättar om sitt eget bidrag: "CER: A Handy Tool for the Civil Engineer", men tar även hjälp av 5 ol