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SAXS/WAXS Investigation of Amyloid-β(16-22) Peptide Nanotubes

This brief report presents an X-ray scattering investigation of self-assembled nanotubes formed by a short peptide. X-ray scattering methods enable multiscale structural elucidation of these nanotubes in solution under the same conditions involved in the self-assembly process. In particular, the dimensions of nanotubes and the crystalline organization within their walls can be determined quantitat

Lupin Protein Isolate Structure Diversity in Frozen-Cast Foams : Effects of Transglutaminases and Edible Fats

This study addresses an innovative approach to generate aerated foods with appealing texture through the utilization of lupin protein isolate (LPI) in combination with edible fats. We show the impact of transglutaminases (TGs; SB6 and commercial), glycerol (Gly), soy lecithin (Lec) and linoleic acid (LA) on the micro- and nanostructure of health promoting solid foods created from LPI and fats blen

Patterns of pathologic lymph nodes in anal cancer : a PET-CT-based analysis with implications for radiotherapy treatment volumes

Background: This study investigates the patterns of PET-positive lymph nodes (LNs) in anal cancer. The aim was to provide information that could inform future anal cancer radiotherapy contouring guidelines. Methods: The baseline [18F]-FDG PET-CTs of 190 consecutive anal cancer patients were retrospectively assessed. LNs with a Deauville score (DS) of ≥3 were defined as PET-positive. Each PET-posit

Dietary intake of trans fatty acids and breast cancer risk in 9 European countries

Background: Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted. Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC),

Dirac states in the noncentrosymmetric superconductor BiPd

Quantum materials having Dirac fermions in conjunction with superconductivity is believed to be the candidate material to realize exotic physics as well as advanced technology. Angle-resolved photoemission spectroscopy (ARPES), a direct probe of the electronic structure, has been extensively used to study these materials. However, experiments often exhibit conflicting results on dimensionality and

Cerebrospinal fluid proteome maps detect pathogen-specific host response patterns in meningitis

Meningitis is a potentially life-threatening infection characterized by the inflammation of the leptomeningeal membranes. Many different viral and bacterial pathogens can cause meningitis, with differences in mortality rates, risk of developing neurological sequelae and treatment options. Here we constructed a compendium of digital cerebrospinal fluid (CSF) proteome maps to define pathogen-specifi

Paliperidone palmitate-induced facial angioedema : A case report

BACKGROUND: Paliperidone palmitate is a once-monthly injectable, atypical antipsychotic. To our knowledge, there has been only one report of paliperidone palmitate-induced angioedema presenting with acute laryngeal edema with subsequent respiratory arrest. Here, we present a case report of paliperidone palmitate-induced angioedema with a relatively mild clinical presentation compared with the prev

Identifying the Drivers of Spatial Taxonomic and Functional Beta-Diversity of British Breeding Birds

Spatial variation in community composition may be driven by a variety of processes, including environmental filtering and dispersal limitation. While work has been conducted on the relative importance of these processes on various taxa and at varying resolutions, tests using high-resolution empirical data across large spatial extents are sparse. Here, we use a dataset on the presence/absence of br

A statistical method for identifying different rules of interaction between individuals in moving animal groups

The emergent patterns of collective motion are thought to arise from application of individual-level rules that govern how individuals adjust their velocity as a function of the relative position and behaviours of their neighbours. Empirical studies have sought to determine such rules of interaction applied by 'average' individuals by aggregating data from multiple individuals across multiple traj

Recent Development in Numerical Simulations and Experimental Studies of Biomass Thermochemical Conversion

Biomass, as a renewable energy source, is available worldwide, is carbon neutral, and can be converted to various types of products depending on the market and on the specific applications. Among different technologies of biomass utilization, thermochemical conversion of biomass is the most efficient method with the shortest time scale of the process. Thermochemical conversion can be used to produ

Perspectives on Care for Late-Stage Parkinson's Disease

In the late stage of Parkinson's disease (PD), there is an increasing disease burden not only for the patients but also for their informal caregivers and the health and social services systems. The aim of this study was to explore experiences of late-stage PD patients' and their informal caregivers' satisfaction with care and support, in order to better understand how they perceive the treatment a

Communicative ability and support important when administrators at the local social insurance office meet disability pensioners

The high rate of disability pensioners is alarming in many industrial countries today. In Sweden the rate was 9.5% of the population aged 16-54 years in March 2005. Through new legislation, which came into force 2000, disability pensioners in Sweden are able to go back to work without jeopardising their benefit. This 'resting disability pension' was used by 0.2% of all disability pensioners in SweThe high rate of disability pensioners is alarming in many industrial countries today. In Sweden the rate was 9.5% of the population aged 16-54 years in March 2005. Through new legislation, which came into force 2000, disability pensioners in Sweden are able to go back to work without jeopardising their benefit. This 'resting disability pension' was used by 0.2% of all disability pensioners in Swe

Estimating the age–metallicity distribution of a stellar sample from the probability distributions of the individual stars

Estimating age distributions, or star formation histories, of stellar populations in the Milky Way is important in order to study the evolution of trends in elemental abundances and kinematics. We build on previous work to develop an algorithm for estimating the age-metallicity distribution which uses the full age-metallicity probability density functions (PDFs) of individual stars. No assumptions