Pseudogenes, nonfunctional copies of genes, evolve fast due the lack of evolutionary pressures and thus appear in several different forms. PseudoGeneQuest is an online tool to search the human genome for a given query sequence and to identify different types of pseudogenes as well as novel genes and gene fragments.

OBJECTIVE. Severe (PiZZ) alpha(1)-antitrypsin (AAT) deficiency is a risk factor for liver disease, i.e. juvenile cirrhosis in infancy, and cirrhosis and hepatoma in adulthood. Little is known about the risk of liver disease in individuals with moderate (PiSZ) AAT deficiency. To investigate the natural course of AAT deficiency, a cohort of PiZZ and PiSZ individuals identified by the Swedish Nationa

In 1867 Alexander Melville Bell conceived the high-low front-back tongue position model for vowels, including the concept of central vowels. This model was rapidly accepted by the phonetics community, but it has never been validated. This article reports an examination of 38 sets of X-ray tracings of vowels from 15 different languages, published in the past half century. This corroborates the char

Att drabbas av cancer blir en påminnelse och ett hot om livets slut. Det finns då ett behov av att navigera i en fragmenterad och okänd livssituation. På okänt cancervatten är en studie baserad på 19 cancerpatienters berättelser om sina vardagsliv. Syftet med studien är att genom öppna intervjuer lyssna och iaktta vad informanterna ansåg viktigt i sina liv. Att förstå och finna mönster i hur de ha

“The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. In the often very emotionally-led debate basically two directly conflicting schools of thoughts can be identified. Some people believe

Phonetic markedness regarding linguistically relevant tonal patterns (Accent 2, boundary tones) in Central Swedish is discussed. Both tonal markedness and F0 turning points are assumed to be important cues for anticipatory attention to grammatical structure during speech processing. Empirical evidence from neuro- linguistic and psycholinguistic experiments for the assumed relation between anticipa

Screening for abdominal aortic aneurysm (AAA) among 65 year old men has been proven cost-effective, but nowadays is conducted partly under new conditions. The prevalence of AAA has decreased, and endovascular aneurysm repair (EVAR) has become the predominant surgical method for AAA repair in many centers. At the Malmö Vascular Center pharmacological secondary prevention with statins, antiplatelet

Purpose: Photodynamic therapy utilising delta-aminoleuvlinic acid-induced protoporphyrin IX photosensitisation, was evaluated as a treatment modality for nonmelanoma skin malignancies of the eyelids and the periocular skin, Methods: Photodynamic therapy with laser light at 635 nm was performed in 13 patients with 19 basal cell carcinomas and one patient with 3 cutaneous T-cell lymphoma lesions. A

Haperende natievorming. Die Unie Tussen Wit-Rusland en Rusland”, temanummer om Vitryssland av den holländska tidskriften Oost-Europa Verkenningen, Mars 2002

This article reports model experiments where vocal tract profiles of high and mid unrounded front and high rounded back vowels were systematically modified to simulate small constriction shifts along the hard or soft palate, in order to test A. M. Bell's century-old proposal that small shifts of tongue arch fronting or retraction would yield audible shifts of vowel timbre. Such differences were cl

Abstract is not available