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Spelberoende är en högaktuell diagnos - Snabba internetspel om pengar har stor beroendepotential – KBT ger god effekt

Gambling disorder is a serious condition and a current issue in Sweden. The national prevalence of problem gambling is 2 %, including 0.4 % meeting criteria for gambling disorder, but the incidence numbers are substantially higher due to the dynamic pattern of the disorder with people moving into and out of the problem gambling group. Rapid internet games, such as internet casinos and sports betti

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

OBJECTIVE: To estimate the prevalence of amyloid positivity, defined by positron emission tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological examination, in primary progressive aphasia (PPA) variants. METHODS: We conducted a meta-analysis with individual participant data from 1,251 patients diagnosed with PPA (including logopenic [lvPPA, n = 443], nonfluent [nfvPPA, n =

Aggressive RF Circuit Reduction Techniques in Millimeter Wave Cellular Systems

In this paper, we introduce a novel hybrid multiuser multiple-input multiple-output (MU-MIMO) architecture, with an emphasis on aggressive millimeter-wave (mmWave) hardware reduction methods, omitting the beam selection stage. We propose a simplification in a 28 GHz Rotman lens, where the number of beam-ports are reduced relative to the array ports resulting in the removal of a bank of RF switches

The 920–900 Ma Bahia-Gangila LIP of the São Francisco and Congo cratons and link with Dashigou-Chulan LIP of North China craton : New insights from U-Pb geochronology and geochemistry

A widespread mafic sill and dyke unit (the Pedro Lessa suite) adjacent to the southeastern São Francisco (SF) craton (eastern South America) is dated as 940 ± 42 Ma, 912 ± 17 Ma, and 986 ± 64 Ma (based on combined ID-TIMS and LA-ICPMS analyses on baddeleyite grains) on the Santa Maria de Itabira gabbroic intrusion. These ages suggest membership in the previously defined ca. 920–900 Ma Large Igneou

Test-retest reliability of the participation domain of the stroke impact scale in persons with chronic stroke

Objective: To evaluate the test-retest reliability and variability of the Participation domain of the Stroke Impact Scale (SIS Participation) in persons with stroke as it is widely used to assess perceived participation in rehabilitation after stroke. Design: A test-retest design. Subjects: Forty-five persons (mean age 65 years) with mild to moderate disability at least 6 months post-stroke. Metho

Routine laparoscopy for nonpalpable testes?

There are still no accepted criteria for the selection of patients with nonpalpable testes for laparoscopy versus a primary surgical exploration. We here report our experience using routine laparoscopy in such patients. The aim was to determine whether laparoscopy should be the first operative intervention or follow an inguinal exploration. Included in the study were 61 boys with 69 nonpalpable te

Two children with xeroderma pigmentosum developing two different types of malignancies simultaneously

Patients with xeroderma pigmentosum (XP) are highly sensitive to ultraviolet radiation and prone to develop multiple skin malignancies. We report two children under 6 years of age with XP who each developed two histologically different types of malignancies simultaneously. We conclude that it is of importance to be aware of the possibility of multiple malignancies of different types, even in young

Single-puncture laparoscopic gastrostomy in children

An original one-puncture technique of performing laparoscopic gastrostomy is described. The implications are analysed. The results of five operations are presented and the advantages and limitations are discussed in the light of current available methods.

Membranous duodenal stenosis

The experience of our 16 patients treated for membranous duodenal stenosis is reported. Their treatment and course was analysed in a retrospective study. Eight patients were operated on within the first 16 days of life and in the remaining group surgery was performed at 1 month to 4 y of age. The presenting symptom leading to diagnosis was, in all but one case, non-bile-stained vomiting. Associate

Role of obstruction in the pathogenesis of acute appendicitis

The role of obstruction in the pathogenesis of acute appendicitis was studied by measuring the pressure in the appendix perioperatively in 24 patients operated on with an appendectomy because of suspected acute appendicitis. The technique used involved inserting a fine needle through the apex into the appendix lumen and measuring the hydrostatic pressure required to inject saline solution. In thre

The host defense peptide LL-37 triggers release of nucleic acids from human mast cells

The human host defense peptide LL-37 possesses antimicrobial activity but also affects host cell function and viability. Mast cells are involved in innate immunity but no data have been presented on effects of LL-37 on human mast cell viability and export of nucleic acids. Here, we demonstrated by immunofluorescence microscopy that synthesized LL-37 was internalized by human LAD2 mast cells and de

Exploiting sensor geometry for enhanced gas sensing properties of fluorinated carbon nanotubes under humid environment

Modification of the surface electronic properties of vertically aligned and randomly distributed carbon nanotubes and the hydrophobic character after exposure to Ar:F2 and CF4 plasma are exploited to optimize the sensing characteristics of these materials. The sensing properties of fluorinated carbon nanotubes are disclosed by probing their stability and responsiveness towards the detection of two

Investigation of mixed convection in an enclosure filled with nanofluids of Al2O3 –water and graphene-ethylene glycol

In this research work, heat transfer enhancement of mixed convection in an enclosure is investigated with a moving top wall. Numerical simulations based on an Al2 O3 –water nanofluid are conducted by using variable thermophysical properties. Flow fields and temperature distributions are analyzed by considering effects of two partially heated walls. Moreover, water–ethylene glycol mixed with graphe

Effect of geomagnetic field on migratory activity in a diurnal passerine migrant, the dunnock, Prunella modularis

Migratory songbirds are guided by an endogenous programme during their first migration, encoding timing of migration, distance and direction. To successfully perform migration, birds have evolved phenotypic adaptations for flight, fuelling and navigation. Migratory distance in different species of birds is encoded as a period of expressed migratory restlessness, for which the length is correlated

Loss of Canonical Notch Signaling Affects Multiple Steps in NK Cell Development in Mice

Within the hematopoietic system, the Notch pathway is critical for promoting thymic T cell development and suppressing the B and myeloid lineage fates; however, its impact on NK lymphopoiesis is less understood. To study the role of Notch during NK cell development in vivo, we investigated different NK cell compartments and function in Rbp-Jkfl/flVav-Cretg/+ mice, in which Rbp-Jk, the major transc