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Phosphatidylethanol in blood (B-PEth): A marker for alcohol use and abuse.

Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues where ethanol by phospholipase D has been bound at the position that normally contains an amino-alcohol. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%. The half-life of PEth in blood is approximately 4 days. The amount

Pancreatic cancer: Translational research aspects and clinical implications.

Despite improvements in surgical techniques and adjuvant chemotherapy, the overall mortality rates in pancreatic cancer have generally remained relatively unchanged and the 5-year survival rate is actually below 2%. This paper will address the importance of achieving an early diagnosis and identifying markers for prognosis and response to therapy such as genes, proteins, microRNAs or epigenetic mo

OH regeneration from methacrolein oxidation investigated in the atmosphere simulation chamber SAPHIR

Hydroxyl radicals (OH) are the most important reagent for the oxidation of trace gases in the atmosphere. OH concentrations measured during recent field campaigns in isoprene-rich environments were unexpectedly large. A number of studies showed that unimolecular reactions of organic peroxy radicals (RO2) formed in the initial reaction step of isoprene with OH play an important role for the OH budg

The Women's Health in the Lund Area (WHILA) study-An overview.

The Women's Health in the Lund Area (WHILA) study invited all women (n=10,766) living in the Lund area of Southern Sweden by 1995, who were born between 1935 and 1945. The health screening program included a postal validated questionnaire concerning medical history, drug treatment, family history of diabetes and hypertension, menopausal status, smoking and alcohol habits, education, household, and

Affinity extraction of dye- and metal ion-binding proteins in polyvinylpyrrolidone-based aqueous two-phase system.

Affinity extraction of dye- and metal ion-binding proteins, respectively, in a polyvinylpyrrolidone (PVP40)-Reppal PES 100 two-phase system was investigated. Due to the ability of PVP to complex azo dyes and inorganic ions, covalent coupling of the ligands was not essential. Cibacron Blue F3GA was used as the ligand for extraction of lactate dehydrogenase (LDH) from porcine muscle, while copper io

Experiences of and views on third-party assurance of corporate environmental and sustainability reports

This study explores the development of environmental and sustainability reporting in Sweden and the dynamics behind the corporate decision to introduce, or not to introduce, third-party assurance of voluntary reports. The results are based on interviews with 28 Swedish companies, an analysis of corporate environmental/sustainability/annuaI reports as well as interviews with assurance providers. Be

The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis

Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action of erythromycin and its derivatives in the treatment of chronic sinusitis and nasa

Optimal control for systems with varying sampling rate

The paper addresses the aspects of control of real time systems with varying sampling rate. An example is given in which a stable continuous system is sampled at two different sampling rates. Two controllers are designed to minimize the same continuous quadratic loss function with the same weights. It is shown that although the design leads to stable controlled closed loop systems, for both discre

The cultured neuroretina: development, survival and transplantation

Popular Abstract in Swedish Näthinnan är den del av ögat som tar emot ljussignaler och omvandlar dem till elektriska signaler. Dessa signaler förs sedan vidare via synnerven till hjärnan för att man skall kunna erhålla en synupplevelse. Näthinnan består av flera celltyper och en av dessa är fotoreceptorcellen, som omvandlar ljus till elektriska signaler, den s.k. fototransduktionen. Den del av fotIn the cultured immature rat full-thickness neuroretina, massive apoptosis appears in the GCL within hours after explantation, but in the ONL cell death is low. Microglia cells become activated when the retina is kept in culture and are found in the GCL within 24 hours of culture. Embryonic porcine retina kept in culture can survive and develop according to its intrinsic timetable for at least si

Temperature-dependent changes in the soil bacterial community in limed and unlimed soil

A humus soil with a pH(H2O) of 4.9 was limed to a pH of 7.5 and was incubated together with samples from unlimed and field limed (pH 6.1) soils at 5, 20 and 30degreesC for up to 80 days. The changes in the phospholipid fatty acid (PLFA) pattern were most rapid for the bacterial community of the soil incubated at 30degreesC, while no changes were found in the soil incubated at 5degreesC. The respon

A proposal to estimate homogeneous and inhomogeneous energy level broadening in double barrier resonant tunneling diodes

In this paper we proposed a method for evaluating a homogeneous broadening (DeltaE(h)) and inhomogeneous broadening (DeltaE(i)) of the resonant energy level width independently by using current-voltage characteristics in double barrier resonant tunneling diodes (DBRTDs). The line shape of the resonant energy broadening is assumed as a convolution of Lorentz function and a Gauss function. Measured

Dynamical systems and commutants in crossed products

In this paper, we describe the commutant of an arbitrary subalgebra A of the algebra of functions on a set X in a crossed product of A with the integers, where the latter act on A by a composition automorphism defined via a bijection of X. The resulting conditions which are necessary and sufficient for A to be maximal abelian in the crossed product are subsequently applied to situations where thes

Extramedullary fixation of 569 unstable intertrochanteric fractures: a randomized multicenter trial of the Medoff sliding plate versus three other screw-plate systems

We compared the efficacy of the Medoff sliding plate (MSP) with 3 other screw-plate systems for fixation of unstable intertrochanteric fractures in a randomized multicenter trial of 569 elderly patients. The MSP has biaxial dynamic capacity along both the neck and the shaft of the femur unlike the other systems, which lack dynamic capacity along the shaft. 268 fractures were operated on with the M

Photoelectrochemical investigation of methylene blue immobilised on zirconium phosphate modified carbon paste electrode in flow injection system

The adsorption of methylene blue (MB) onto zirconium phosphate (ZrP) was studied and the adsorption capacity value and isotherms were determined. The adsorption capacity of ZrP was increased after being exposed to gas phase n-butyl amine. The adsorbed MB on ZrP was used as a modifier material in carbon paste electrode (MCPE), which in turn was used in voltammetric investigations and flow injection

The disabilities of the arm, shoulder and hand (DASH) outcome questionnaire: reliability and validity of the Swedish version evaluated in 176 patients

The disabilities of the arm, shoulder and hand (DASH) questionnaire is a self-administered region-specific outcome instrument developed to measure upper-extremity disability and symptoms. The DASH consists mainly of a 30-item disability/symptom scale. We performed cross-cultural adaptation of the DASH to Swedish, using a process that included double forward and backward translations, expert and la