We present a summary of late Paleoproterozoic to Neoproterozoic mafic magmatism in the Siberian craton, including recently published U-Pb and Ar-40-Ar-39 dates. These new precise ages suggest that at least some of the previously published K-Ar ages of Siberian mafic bodies should be ignored. The time-space geochronological chart, or the 'barcode' of mafic magmatic events shows significant differen

Requirements for patient safety and improved efficacy are steadily increasing in modern healthcare and are key drivers in modern drug development. New drug characterization assays are central in providing evidence of the specificity and selectivity of drugs. Meeting this need, matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) is used to study drug localization withi

Experiments are carried out on partially premixed turbulent flames stabilized in a conical burner. The investigated gaseous fuels are methane, methane diluted with nitrogen, and Mixtures of CH4, CO, CO2, H-2 and N-2, Simulating typical products from gasification of biomass, and co-firing of gasification gas with methane. The fuel and air are partially premixed in concentric tubes. Flame stabilizat

National greenhouse-gas accounting should reflect how countries’ policies and behaviours affect global emissions. Actions that contribute to reduced global emissions should be credited, and actions that increase them should be penalized. This is essential if accounting is to serve as accurate guidance for climate policy. Yet this principle is not satisfied by the two most common accounting methods

The literature on trade facilitation has mostly focused on implications for trade volumes. However, recent theoretical contributions have emphasized that trade costs – such as transaction costs related to cross-border trade procedures – affect both the traded volumes of “old” goods (the intensive margin) and the range of traded goods (the extensive margin). This paper therefore tests whether trade

Resource use conflict is an enduring problem for science and policy making. Using in-depth interviews and focus group discussions with resource users, policy makers and key informants, we explored four case examples of resource use conflict within lands and forestry, fisheries, oil and the mining sectors in Ghana. Results indicate that resource use conflict consists of a complex, non-linear system

Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up (additional 137,052 individuals) in a total of

Background: Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence is lacking. Methods: This prospective cohort study and meta-analysis of existing studies investigated the association between PA and mortality in individuals with diabetes. In the EPIC study (European Prospective Investigation Into Cancer and Nutrition),

We introduce a simple method for detecting outliers in Data Envelopment Analysis. The method is based on two scalar measures. The first is the relative frequency with which an observation appears in the construction of the frontier when testing the efficiency of other observations, and the second is the cumulative weight of an observation in the construction of the frontier. We provide a link to c

During the hours of darkness, the mobility of young women, the elderly and the disabled is limited in urban areas. In a field study possible predictors of the perceived visual accessibility and the perceived danger of an urban footpath were investigated. Eighty-one people individually walked along the footpath after dark. They subjectively assessed the environment and answered a questionnaire abou

Little is known about the association between neighborhood linking social capital and psychiatric medication in the elderly. The present study analyzes whether there is an association between linking social capital (a theoretical concept describing the amount of trust between individuals and societal institutions) and prescription of antipsychotics, anxiolytics, hypnotics/sedatives, antidepressant

Vacuum-assisted wound closure (VAC) therapy may heal wounds faster than conventional dressings after surgical debridement of perivascular groin infections after vascular surgery.

In this study we investigated the impact of water uptake by aerosol particles in ambient atmosphere on their optical properties and their direct radiative effect (ADRE, W m(-2)) in the Arctic at Ny-Alesund, Svalbard, during 2008. To achieve this, we combined three models, a hygroscopic growth model, a Mie model and a radiative transfer model, with an extensive set of observational data. We found t

Background. The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period. In the present study, we hypothesized that OCs would be related to cortical f

Phenological changes among plants due to climate change are well documented, but often hard to interpret. In order to assess the adaptive value of observed changes, we study how annual plants with and without growth constraints should optimize their flowering time when productivity and season length changes. We consider growth constraints that depend on the plant's vegetative mass: self-shading, c