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Physics informed stochastic grey-box model of the flow-front in a vacuum assisted resin transfer moulding process with missing data

Real-time fault monitoring and control of the Vacuum Assisted Resin Transfer Moulding production process requires knowledge of the position of the epoxy flow-front inside the mould. Therefore, a fast and accurate flow-front tracking system is highly prized. Physics-informed grey-box models deliver a good trade-off between high fidelity and data-driven black-box models for designing such a flow-fro

Extramedullary Cavernous Hemangioma with Intradural and Extradural Growth and Clinical Symptoms of Brown-Séquard Syndrome: : Case Report and Review of the Literature

Background: Primary spinal tumors are rare. Symptoms depend on the size and location of the tumor.Case description: A patient presented with a rare clinical finding, Brown-Séquard syndrome. The symptoms were caused by an extramedullary tumor compressing on the thoracic spinal cord. Pathologic examination showed cavernous hemangioma with growth both intradurally and extradurally.Conclusions: This i

Use of 3 Dimensional Models and Navigation System in Preparation for Brain Surgery

This paper shows the advantage of using both 3d models and surgical navigation system when preparing and planning complex brain surgery. The novel clinical process introduced here combine CT and MRI images in special computer program where the regions of interest are isolated e.g. the skull base, tumor and other soft tissue. A 3D model is calculated from the segmented masks and printed using Rapid

Solitary retroperitoneal ganglioneuroma

Retroperitoneal tumours rarely cause significant symptoms, therefore they are frequently diagnosed incidentally. Ganglioneuroma is a rare tumour that most often present in the posterior mediastinum or the retroperitoneal cavity. In the present case, a solitary ganglioneuroma is diagnosed in the retroperitoneum in an young healthy male, a rather typical presentation of this benign tumour.

Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities

Background: Among sarcomas, which are rare cancers, many types are exceedingly rare; however, a definition of ultra-rare cancers has not been established. The problem of ultra-rare sarcomas is particularly relevant because they represent unique diseases, and their rarity poses major challenges for diagnosis, understanding disease biology, generating clinical evidence to support new drug developmen

Risk for overexploiting a seemingly stable seal population : influence of multiple stressors and hunting

Conservation efforts have mainly been focused on depleted species or populations, but many formerly reduced marine mammal populations have recovered to historical abundances. This calls for new management strategies and new models for ecological risk assessment that incorporate local density dependence and multiple environmental stressors. The harbor seal metapopulation in Swedish and Danish water

Different Responses to Neoadjuvant Chemotherapy in Urothelial Carcinoma Molecular Subtypes

BACKGROUND: For muscle-invasive bladder cancer (MIBC), no tissue biomarkers are available for clinical use to predict response to neoadjuvant chemotherapy.OBJECTIVE: To investigate how molecular subtypes impact pathological response and survival in patients receiving preoperative cisplatin-based chemotherapy.DESIGN, SETTING, AND PARTICIPANTS: Classification of a retrospective cohort of 149 patient

Cationic photoinitiated copolymerization of 1-propenyl-vinyl ether systems

A kinetic investigation of the photoinitiated cationic copolymerization of 1-propenyl ethers with vinyl ethers monomers was performed by using FT-IR and 1H-NMR analysis. FT-IR results, obtained in bulk, indicate a higher reactivity of the vinyl ether with respect to the 1-propenyl ether double bond. 1H-NMR analysis, in CDCl3 solution, confirms these results which agree with the literature data con

Retoriska övningar för demokrati

Alla svenska lärare har enligt skollagen ett dubbelt uppdrag, kunskapsuppdraget och demokratiuppdraget. Demokratiuppdraget uppfattas som problematiskt av utvärderande myndigheter, lärare och skolans huvudmän. Alla gymnasielärare i svenska ska enligt senaste läroplanen GY11 explicit arbete med retorik. Finns det retoriska övningar som kan integrera såväl litteratur- och språkundervisning med demokr

A comparison of rule-based and centroid single-sample multiclass predictors for transcriptomic classification

MOTIVATION: Gene expression-based multiclass prediction, such as tumor subtyping, is a non-trivial bioinformatic problem. Most classifier methods operate by comparing expression levels relative to other samples. Methods that base predictions on the expression pattern within a sample have been proposed as an alternative. As these methods are invariant to the cohort composition and can be applied to

The Price of Synchrony : Evaluating the Resistive Losses in Synchronizing Power Networks

This paper investigates the resistive power losses that are incurred in keeping a network of synchronous generators in a synchronous state. These losses arise due to the transient power-flow fluctuations that occur when the system is perturbed from a synchronous state by a small transient event or in the face of persistent stochastic disturbances. We call these losses the 'price of synchrony,' as

Diagnostic and prognostic implications of a three-antibody molecular subtyping algorithm for non-muscle invasive bladder cancer

Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the

Article leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profiling

Multiple biotic and abiotic stresses challenge plants growing in agricultural fields. Most molecular studies have aimed to understand plant responses to challenges under controlled conditions. However, studies on field-grown plants are scarce, limiting application of the findings in agricultural conditions. In this study, we investigated the composition of apoplastic proteomes of potato cultivar B

Speech in a consecutive series of children born with cleft lip and palate with and without syndromes and/or additional malformations

BACKGROUND: When evaluating speech in children with cleft palate with or without cleft lip (CP/L), children with known syndromes and/or additional malformations (CP/L+) are usually excluded. The aim of this study was to present speech outcome of a consecutive series of 5-year-olds born with CP/L, and to compare speech results of children with CP/L + and children with CP/L without known syndromes a