BACKGROUND: The transport of large proteins across the glomerular capillary wall (GCW) may increase several fold in glomerular diseases. The occurrence of IgM in urine is a consequence of the presence of large defects or shunts in the GCW, whereas albuminuria is probably a result of an altered charge- and size-selectivity of the GCW. In order to examine whether patho-morphological differences infl

Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.

Silicon microtechnology has been used to develop a microstructure toolbox in order to enable high accuracy protein identification. During the last 2 years we developed and applied monocrystalline silicon structures and established new automated protein analysis platforms, The development of a high throughput protein platform is presented where fully automated protein identifications are performed.

Strange quarks produced in e+e--annihilation at the Z0-pole are very strongly polarized. To study to which extent this polarization is transferred to the observable hadrons would give interesting information on the hadronization mechanism. Γ-particles produced with relatively large x-values are expected to frequently contain an originally produced s-quark. We estimate that Γ-particles with x>0.3 s

2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.

This thesis is a critique of the New Institutional Economics (NIE) in economic history. The focus is on explanations to the origin and development of capitalist institutions within NIE. After a methodological discussion in chapter 1 the author investigates into how well NIE succeeds in explaining capitalist institutions. In chapters 2 and 3, a conceptual critique of the theoretical bases of evolu

Objective: To examine and compare the adult outcome in a representative sample of hospitalized adolescent-onset psychoses including occupational and social aspects. Method: A total of 81 patients with a first episode of early-onset psychosis (before age 19 years) presenting to the University Hospital of Lund, Sweden, between 1982 and 1993 were followed up an average of 10.5 years (range 5.1-18.2)

Artikeln behandlar de svårigheter som uppstår i den offentliga debatten av konstutställningar när ämnet för utställningen är sexualiteter utanför den heterosexuella normaliteten. De bägge utställningar som behandlas, Donald Maders medverkan i Bjarne Mellgaards "Softcore" och Elisabeth Olsson-Wallins "Ecce Homo", väckte båda mycket starka reaktioner. Essän reder ut hur denna storm tar sin form i de

The modelling of premixed turbulent combustion has been studied. Premixed turbulent combustion occurs in a range of applications, such as gas turbines and spark-ignition engines. It is important that the modelling can capture the most relevant details of the combustion in order to minimize the emissions and secure the operability already in the design process of these devices. As the simulation of

Cooperatively breeding birds tend to exhibit high adult survival and relatively small clutch sizes. According to the life-history hypothesis for cooperative breeding, high survival creates conditions for philopatry based on difficulties that dispersers face when competing for territories in a landscape with slow territory turnover. However, this hypothesis evokes a puzzle because high fecundity sh

In supersymmetric scenarios with broken R-parity, baryon number violating sparticle decays become possible. In order to search for such decays, a good understanding of expected event properties is essential. We here develop a complete framework that allows detailed studies. Special attention is given to the hadronization phase, wherein the baryon number violating vertex is associated with the appe

Src homology 2 (SH2) domains recognize phosphotyrosine (pY)-containing sequences and thereby mediate their association to ligands. Bruton's tyrosine kinase (Btk) is a cytoplasmic protein tyrosine kinase, in which mutations cause a hereditary immunodeficiency disease, X-linked agammaglobulinemia (XLA). Mutations have been found in all Btk domains, including SH2, We have analyzed the structural and

Popular Abstract in Swedish Döva barns begreppsbildning i matematik Denna studie tar utgångspunkt i frågan varför många döva barn har svårt att lära sig matematik. Studiens syfte är att belysa döva barns begreppsbildning i ämnet matematik genom att beskriva hur några döva barn uttrycker sig och agerar på väg mot förståelse av två centrala matematiska begrepp, nämligen multiplikation med heltal ochThe question why deaf children have difficulties in learning mathematics is the basis of this study. The aim of the study is to illuminate deaf children’s concept formation in mathematics by describing how some deaf children express themselves and act on their way towards understanding two basic concepts, the concept of multiplication with whole numbers and the concept of length. Theories develope

The NOx storage and reduction approach was applied on a full-scale engine rig under stationary operation. NOx reduction experiments were performed and a catalyst model developed and tested. The exhaust system was equipped with a bypass system. A NOx reduction of 25-53% was achieved. At low temperature, higher values were reached when the exhaust gas bypass was longer than the injection period.

In the previous study, we investigated effect of physical state of nonpolar lipids of gluten-starch model dough. This experiment examined a real wheat flour dough system to assess the role of fat crystals in the breadmaking processes. These experiments were performed with a baking test and an investigation of wheat flour dough through rheological measurements (both large and small deformations), s