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The diagnostic utility of DNA copy number analysis of core needle biopsies from soft tissue and bone tumors

Morphologic and immunohistochemical analysis of preoperative core needle biopsies (CNB) is important in the management of patients with soft tissue and bone tumors (STBTs). Most SBTB subtypes have more or less extensive DNA copy number aberrations (CNA), potentially providing useful diagnostic information. To evaluate the technical feasibility of single nucleotide polymorphism (SNP) array analysis

The Effect on Room Acoustical Parameters Using a Combination of Absorbers and Diffusers : An Experimental Study in a Classroom

Several room acoustic parameters have to be considered in ordinary public rooms, such as offices and classrooms, in order to present the actual conditions, thus increasing demands on the acoustic treatment. The most common acoustical treatment in ordinary rooms is a suspended absorbent ceiling. Due to the non-uniform distribution of the absorbent material, the classical diffuse field assumption is

The Difference in Subjective Experience Related to Acoustic Treatments in an Ordinary Public Room : A Case Study

In ordinary public rooms absorbent ceilings are normally used. However, reflective material such as diffusers can also be useful to improve the acoustic performance for this type of environment. In this study, different combinations of absorbers and diffusers have been used. The study investigates whether a test group of 29 people perceived sound in an ordinary room differently depending on the ty

Molecular Subtypes as a Basis for Stratified Use of Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer—A Narrative Review

There are no established biomarkers to guide patient selection for neoadjuvant chemotherapy prior to radical cystectomy for muscle-invasive bladder cancer. Recent studies suggest that molecular subtype classification holds promise for predicting chemotherapy response and/or survival benefit in this setting. Here, we summarize and discuss the scientific literature examining transcriptomic or panel-

Reaction Mechanisms and Dynamics in the Early Stage of High-κ Oxide Atomic Layer Deposition : Investigations by In Situ and Operando X-ray Photoemission Spectroscopy

Atomic layer deposition (ALD) is an outstanding deposition technique to deposit highly conformal and uniform thin films with atomic precision. In particular, ALD of transition metal oxide layers from metal amido complexes and water finds its way in several technological fields, including green energy devices and in the semiconductor industry. These ALD reactions are believed to follow a reaction s

Children’s advocacy centre fails to respond to dental, mental and physical ill-health in abused children

Aim: Sweden´s first multidisciplinary children's advocacy centre (CAC) was founded in 2005 as a collaborative practice between child protection services, the legal system and health care in response to police-reported child abuse. CACs were introduced in the county of Skåne in 2007. The aim of the study was to describe the health of children investigated at the CAC in Lund, and to examine whether

Complex community-wide consequences of consumer sexual dimorphism

Sexual dimorphism is a ubiquitous source of within-species variation, yet the community-level consequences of sex differences remain poorly understood. Here, we analyse a bitrophic model of two competing resource species and a sexually reproducing consumer species. We show that consumer sex differences in resource acquisition can have striking consequences for consumer-resource coexistence, abunda

Cyclic l-lactide synthesis from lignocellulose biomass by biorefining with complete inhibitor removal and highly simultaneous sugars assimilation

Cyclic chiral lactide is the monomer chemical for polymerization of high molecular weight polylactic acid (PLA). The synthesis of cyclic l-lactide starts from poly-condensation of l-lactic acid to a low molecular weight prepolymer and then depolymerized to cyclic l-lactide. Lignocellulose biomass is the most promising carbohydrate feedstock for lactic acid production, but the synthesis of cyclic l

Midsagittal corpus callosal thickness and cognitive impairment in Parkinson's disease

People diagnosed with Parkinson's disease (PD) can experience significant neuropsychiatric symptoms, including cognitive impairment and dementia, the neuroanatomical substrates of which are not fully characterised. Symptoms associated with cognitive impairment and dementia in PD may relate to direct structural changes to the corpus callosum via primary white matter pathology or as a secondary outc

Public Support for the Euro and Trust in the ECB : The First Two Decades of the Common Currency

This contribution examines the evolution of public support for the euro since its introduction as a virtual currency in 1999, using a unique set of data not available for any other currency. We focus on the role of economic factors in determining the popularity of the euro. We find that a majority of citizens support the euro in each individual member country of the euro area (EA). The economic cr