Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4
Popular Abstract in Swedish Inflammationsreaktioner kan utlösas i alla vävnader som ett generellt svar på olika stimuli. En defekt eller utebliven reaktion kan leda till svåra infektion sjukdomar. De olika stimuli som startar den inflammatoriska processen frisätter olika inflammationsmediatorer i vävnaden. Dessa kan vara lagrade i celler och frisätts till omgivningen. Vad gäller arachidonsyra prodLeukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. Cell-cell and cell-matrix complexes of epithelial cells are inter
