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Popular Abstract in Swedish Diabetes kännetecknas av förhöjda halter av glukos i blodet och flera vanliga former förekommer. Typ 1 (T1D) diabetes är vanligast förekommande hos barnoch ungdomar och karakteriseras av att de insulin producerande cellerna (s.k. betacellerna) förstörs av kroppens eget immunförsvar, en autoimmun reaktion. Patienter med T1D diabetes kräver insulin för överlevnad och har T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring

Purpose: To study the effect of AED exposure on head circumference in the newborn. Methods: Data on all Swedish singletons births between 1995 and 2005, over 900,000 births, were obtained from the Swedish Medical Birth Registry. The effects of AEDs on birth-weight-adjusted mean head circumference (bw-adj-HC) were estimated by comparison with data from all births in an analysis which was adjusted f

Research on organizational change often focuses on the nature and causes of employee objections to change, typically referred to as resistance. This paper explores managerial assumptions in this regard, suggesting a conceptual framework whereby employee objections are understood as whistle-blowing, opinion, resistance/trauma or resistance/disposition. Furthermore, it shows how each position provid

This study aimed to comprehensibly investigate potential contributing factors to fear of falling (FOF) among people with idiopathic Parkinson's disease (PD).

Contemporary methods of atrial flutter (AFL), atrial tachycardia (AT), and atrial fibrillation (AF) monitoring, although superior to the standard 12-lead ECG and symptom-based monitoring, are unable to accurately discriminate between AF, AFL and AT. Thus, there is a need to develop accurate, automated, and comprehensive atrial arrhythmia detection algorithms using standard ECG recorders. To this e

The progressive development of Alzheimer's disease (AD) pathology follows a spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP) with the arctic (E693G) mutation, pathology spreads along anatomically connected structures. Amyloid-β (Aβ) pathology first appears in the subiculum and is later detected in interconnected brain regi

We prove sharp estimates for the Bergman projection in weighted Bergman spaces in terms of the Bekolle constant. Our main tools are a dyadic model dominating the operator and an adaptation of a method of Cruz-Uribe, Martell and Perez. (C) 2013 Elsevier Inc. All rights reserved.

Organ transplantation may lead to secondary osteoporosis in children. This study characterized bone histomorphometric findings in pediatric solid organ transplant recipients who were assessed for suspected secondary osteoporosis. Iliac crest biopsies were obtained from 19 children (7.6-18.8 years, 11 male) who had undergone kidney (n = 6), liver (n = 9), or heart (n = 4) transplantation a median 4

To validate cardiac output measurements by ultrasound dilution technology (COstatus monitor) against those obtained by a transit-time ultrasound technology with a perivascular flow probe and to investigate ultrasound dilution ability to estimate pulmonary to systemic blood flow ratio in children.

Background: When compared to the other mismatch repair genes involved in Lynch syndrome, the identification of mutations within PMS2 has been limited (<2% of all identified mutations), yet the immunohistochemical analysis of tumour samples indicates that approximately 5% of Lynch syndrome cases are caused by PMS2. This disparity is primarily due to complications in the study of this gene caused by

Objective To determine if the prediction of the Malignancy of all adnexal mass using pattern recognition, i.e. subjective evaluation of gray-scale and Doppler ultrasound findings, is as accurate when based on static images as it is when based on a real-time ultrasound examination. Methods The static images of 166 non-consecutive patients with 'difficult' adnexal masses, who all underwent surgery a

Industry involvement in open source software development has become a popular practice among companies which, e.g., share software development costs with other community participants or implement an open source based business model. An increased understanding of the underlying development structure, especially in a case where the community participants are composed of competing industry members, c

We investigate electrical properties of self-assembled branched InAs nanowires. The branched nanowires are catalytically grown using chemical beam epitaxy, and three-terminal nanoelectronic devices are fabricated from the branched nanowires using electron-beam lithography. We demonstrate that, in difference from conventional macroscopic junctions, the fabricated self-assembled nanowire junction de

Abstract in UndeterminedJavaScript has gone from being a mechanism for providing dynamic web pages to an important component of many web applications. Currently one of the most popular type of web applications is so-called social networks, e.g., Facebook, Twitter, and MySpace. However, the workload and execution behavior of JavaScript in this context have not been fully explored or understood.In t

The aim of this paper is to integrate spatial cognition with lexical semantics. We develop cognitive models of actions and events based on conceptual spaces and vectors on them. The models are then used to present a semantic theory of verbs. We propose a two-vector model of events including a force vector and a result vector. We argue that our framework provides a unified account for a multiplicit