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Cytotoxic terpenoids from Dasyscyphus niveus

Three novel tetracyclic terpenoids, of which two possess potent cytotoxic activities towards various mammalian cell lines, were isolated front extracts of the fermentation broth of the ascomycete Dasayscyphus niveus. The structures of the compounds, named dasyscyphins A-C, were determined with spectroscopic techniques. (c) 2005 Elsevier Ltd. All rights reserved.

New spectroscopic data on Cd-102

Gamma ray spectroscopy of neutron deficient nuclei close to the doubly magic nucleus Sn-100 has been performed using a heavy-ion reaction and the NORDBALL Ge-detector array. Evaporation residues were identified by means of charged particle and neutron detection. Transitions in 31 different evaporation residues were identified. New results on Cd-102 are presented.

A desorption calorimetric method for use at high water activities

This paper presents a microcalorimetric technique to simultaneously measure water activity and enthalpy of mixing (differential heat of sorption) as functions of composition at high water activities. The instrument consists of a sorption vessel in a double twin microcalorimeter. A sample at high water activity is placed in one chamber of the vessel and an unsaturated salt solution is injected into

Preparation of a crystallizable mRNA-binding fragment of Moorella thermoacetica elongation factor SelB

SelB is a bacterial elongation factor required for the decoding of a UGA stop codon together with a specific mRNA hairpin to selenocysteine. In attempts to crystallize Moorella thermoacetica SelB, a proteolysis process occurred and crystals of a proteolytic fragment were observed. The crystals, which appeared after a year, contained a C-terminal 30 kDa fragment containing the mRNA-binding domain.

Analysis of Btk mutations in patients with X-linked agammaglobulinaemia (XLA) and determination of carrier status in normal female relatives: a nationwide study of Btk deficiency in Greece

Bruton's tyrosine kinase (Btk) is a nonreceptor tyrosine kinase, critical for B-cell development and function. Mutations that inactivate this kinase were found in families with X-linked agammaglobulinaemia (XLA). In this study the Btk gene was analyzed in 13 registered Greek patients with XLA phenotype originated from 12 unrelated families, in order to provide a definite diagnosis of the XLA. The

När togs lundakanikernas Consuetudines egentligen i bruk. Reflektioner kring texttradering och traditionsförmedling i 1120-talets Lund [with a summary in English]

On the origin, use and dating of the customary of the cathedral chapter of Lund, i.e. the Consuetudines Lundenses. I have argued that the consuetudines were used by the canons from 30 June 1123 at the latest, the day of inauguration of the crypt church. This seems even more plausible as the prototype of the text, i.e. the Consuetudines Marbacenses, were recently antedated. Furthermore, these circu

Test of four different experimental methods to determine sorption isotherms

One important property of materials is their moisture fixation capacity, i.e., their ability to hold moisture at different relative humidities. The sorption isotherm is one of the main input data in moisture diffusion models, and it can also be used to evaluate properties of the microstructure. We have used four different methods to measure the sorption isotherm of sandstone and porous glass. The

Hyponatremia in elderly patients treated with desmopressin for nocturia: a review of a case series

Objective: Lately, desmopressin (dDAVP) administered orally has been demonstrated to be an effective alternative in the management of nocturia in adults. Although the safety profile of dDAVP is well known, much of the experience originates from studies in enuretic children and younger adults, and it may not be readily extrapolated to elderly patients. In order to identify factors associated with a

Two-stage steam pretreatment of willow for increased pentose yield

A two-stage procedure for pretreatment of fast-growing willow with steam has been investigated. The first stage was performed at temperatures in the range 180°C to 220°C for times between 6 and 10 minutes while the second stage was performed at 220°C for 10 minutes. The fibrous material was washed between the two stages to remove the pentosans and thus increase the pentose yield. The pretreatment

Golv på mark

I denna skrift ges en heltäckande beskrivning av de byggnadsfysikaliska förhållandena i konstruktioner med golv på mark. Olika fuktbelastningar och deras konsekvenser beskrivs i detalj. Stor vikt läggs vid att skapa förståelse för olika byggnadsfysikaliska samband, speciellt mellan värme och fukt. Vidare tillämpas fuktdimensioneringsmetodiken på tre noggrant beskrivna grundkonstruktioner

Veno-right ventricular bypass as total extracorporeal lung assistance. An experimental study

Efficacy of veno-right ventricular bypass as a total extracorporeal lung assistance was studied for a period of 24 hours in six healthy pigs with a mean weight of 60 kg. A covalently bonded heparin-coated extracorporeal membrane oxygenation system and a roller pump were used for the bypass. No local or systemic heparin was administered. The bypass was established with an open chest with two 28F ve

Trade, Competition and Productivity

Popular Abstract in Swedish Avhandlingen består av fyra kapitel som behandlar olika aspekter av internationell handel och dess effekter på konkurrens och produktivitet. Särskilt behandlas effekterna av EU:s expansion och fördjupade integration. Första kapitlet använder den så kallade gravitationsmodellen för att analysera hur integrationsprocessen av de Central- och Östeuropeiska länderna i EU haThis thesis consists of four papers on trade, competition and productivity with particular emphasis on the effects of various aspects of the deepening and widening of the European Union. The first paper Trade Creation, Diversion and Displacement of the EU Enlargement Process provides an assessment of the effects of the EU enlargement process on trade. A new method of estimating the gravity model

Automated detection of fundus photographic red lesions in diabetic retinopathy

PURPOSE. To compare a fundus image-analysis algorithm for automated detection of hemorrhages and microaneurysms with visual detection of retinopathy in patients with diabetes. METHODS. Four hundred fundus photographs (35-mm color transparencies) were obtained in 200 eyes of 100 patients with diabetes who were randomly selected from the Welsh Community Diabetic Retinopathy Study. A gold standard re

Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum

Ca2+ sensitization of smooth muscle contraction involves the small GTPase RhoA, inhibition of myosin light chain phosphatase (MLCP) and enhanced myosin regulatory light chain (LC20) phosphorylation. A potential effector of RhoA is Rho-associated kinase (ROK). The role of ROK in Ca2+ sensitization was investigated in guinea-pig ileum. Contraction of permeabilized muscle strips induced by GTPgammaS