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The gift of being chosen

We report evidence from an experiment where an employer selects one of two workers to perform a task for a fixed compensation. Workers differ in their ability. The employer’s payoff depends on the worker’s ability and on a non-contractible effort that the worker exerts once employed. We find that selected workers exert an effort higher than the minimum enforceable one. When the employers can send

Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.

Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have investigated genetic and epigenetic mechanisms independently, and studies examining their interactions throughout the human genome are lacking. To identify genetic loci that interact with the epigenome, we performed the first genome-wide DNA methylati

Bonding in intermetallics may be deceptive – the case of the new type structure Au2InGa2

We have investigated the crystal and the electronic structure of a new ternary phase, Au2InGa2 using powder and single crystal X-Ray Diffraction (XRD) and Stuttgart Tight Binding LMTO-ASA methods, respectively. Complementary methods including Thermo-Gravimetric Differential Thermal Analysis (TG-DTA), Energy Dispersive X-ray Spectroscopy (EDS) and Scanning Electron Microscopy (SEM) were also employ

FicTrac: A visual method for tracking spherical motion and generating fictive animal paths

Studying how animals interface with a virtual reality can further our understanding of how attention, learning and memory, sensory processing, and navigation are handled by the brain, at both the neurophysiological and behavioural levels. To this end, we have developed a novel vision-based tracking system, FicTrac (Fictive path Tracking software), for estimating the path an animal makes whilst rot

Photoreceptor Differentiation following Transplantation of Allogeneic Retinal Progenitor Cells to the Dystrophic Rhodopsin Pro347Leu Transgenic Pig

Purpose. Transplantation of stem, progenitor, or precursor cells has resulted in photoreceptor replacement and evidence of functional efficacy in rodent models of retinal degeneration. Ongoing work has been directed toward the replication of these results in a large animal model, namely, the pig. Methods. Retinal progenitor cells were derived from the neural retina of GFP-transgenic pigs and trans

Inclusive and exclusive observables from dipoles in high energy collisions

In a series of papers we have developed a Monte Carlo model based on Mueller's dipole picture of BFKL-evolution, supplemented with non-leading corrections, which has shown to be very successful in describing inclusive and semi-inclusive observables in hadron collisions. In this paper we present a further extension of this model to also describe exclusive final states. This is a highly non-trivial

Charge and energy flows in ionised thymidine

We present a combined experimental and theoretical study of the ionisation and fragmentation of the nucleoside thymidine in the gas phase. Two sources of ionisation/excitation are used, namely UV photons and low-energy multiply charged ions, associated with coincidences measurements, respectively photoelectron/photofragment (PEPICO) and fragment/fragment. Coupling these experiments with quantum ch

Preoperative staging of locally advanced bladder cancer before radical cystectomy using 3 tesla magnetic resonance imaging with a standardized protocol

Objective. The correlation between clinical tumour stage and pathological tumour stage in radical cystectomy specimens in locally advanced bladder cancer is suboptimal. Radiological methods have so far been of limited value in preoperative staging; however, the resolution with magnetic resonance imaging (MRI) has improved with further technical developments of the method. The aim of this study was

Smoking Predicts Incident Fractures in Elderly Men: Mr OS Sweden

The aim of this study was to investigate the association between smoking and bone mineral density (BMD) and radiographically verified prevalent vertebral fractures and incident fractures in elderly men. At baseline 3003 men aged 69 to 80 years of age from the Swedish Mr Os Study completed a standard questionnaire concerning smoking habits and had BMD of the hip and spine measured using dual-energy

Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct

Consumption of sugar-sweetened beverages has been shown, largely in American populations, to increase type 2 diabetes incidence. We aimed to evaluate the association of consumption of sweet beverages (juices and nectars, sugar-sweetened soft drinks and artificially sweetened soft drinks) with type 2 diabetes incidence in European adults. We established a case-cohort study including 12,403 incident

Risk of Cancer of Unknown Primary after Hospitalization for Autoimmune Diseases.

Cancer of unknown primary (CUP) is a heterogeneous syndrome diagnosed at metastatic sites. The etiology is unknown but immune dysfunction may be a contributing factor. Patients with autoimmune diseases were identified from the Swedish Hospital Discharge Register and linked to the Swedish Cancer Registry. Standardized incidence ratios (SIRs) were calculated for subsequent CUP and compared with subj

Optimal topologies derived from a phase-field method

Abstract in UndeterminedA topology optimization method allowing for perimeter control is presented. The approach is based on a functional that takes the material density and the strain field as arguments. The cost for surfaces is included in the functional that is minimized. Diffuse designs are avoided by introducing a penalty term in the functional that is minimized. Equilibrium and a volume cons

Extended Proper Orthogonal Decomposition for Analysis of Unsteady Flames

The aim of this work is to present the use of proper orthogonal decomposition (POD) and extended proper orthogonal decomposition (EPOD) for revealing flame dynamics as a set of statistical quantities referred as modes. The flame fluctuations are used to derive an empirical functions base representing the most important features of the flame. The capabilities of the technique are exemplified in the

Fungal activities of indoor moulds on wood as a function of relative humidity during desorption and adsorption processes

Activities of moulds from domestic dwellings are normally classified into three groupsprimary, secondary, and tertiary colonizersaccording to the minimum relative humidity they require to colonize a substrate. With the help of isothermal calorimetry it is possible to directly measure the thermal activity from moulds as a function of climatic parameters. This makes it possible to provide more preci

A paleomagnetic and U-Pb geochronology study of the western end of the Grenville dyke swarm: Rapid changes in paleomagnetic field direction at ca. 585 Ma related to polarity reversals?

A paleomagnetic study of the western end of the similar to 585 Ma Grenville dyke swarm shows that individual dykes are characterized by high coercivity and unblocking temperature magnetizations that can differ in direction by as much as 90 degrees. Field tests including baked contact studies and the continuity of paleomagnetic direction along dyke strike, suggest that the magnetizations are primar

A multi-model study of impacts of climate change on surface ozone in Europe

The impact of climate change on surface ozone over Europe was studied using four offline regional chemistry transport models (CTMs) and one online regional integrated climate-chemistry model (CCM), driven by the same global projection of future climate under the SRES A1B scenario. Anthropogenic emissions of ozone precursors from RCP4.5 for year 2000 were used for simulations of both present and fu

Dissociative tendencies and individual differences in high hypnotic suggestibility.

Introduction. Inconsistencies in the relationship between dissociation and hypnosis may result from heterogeneity among highly suggestible individuals, in particular the existence of distinct highly suggestible subtypes that are of relevance to models of psychopathology and the consequences of trauma. This study contrasted highly suggestible subtypes high or low in dissociation on measures of hypn

Clinical presentation of infective endocarditis caused by different groups of non-beta haemolytic streptococci.

Streptococci are common causes of infective endocarditis (IE) and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has provided a practical tool for their species determination. We aimed to investigate if particular groups of non-beta heamolytic streptococci were associated with IE or to specific presentations thereof. The Swedish Registry of Infective En