Particulate matter emission factors from vehicle brakes are difficult to assess directly from the field. Moreover, there is a lack of a standardized cycle and test stand for evaluating brake emissions. For these reasons, a test cycle was developed from real driving data collected from a car. This new test cycle was implemented on an inertia disc brake dynamometer appositely designed for brake part

AimTo assess the prevalence, types and indications for fluid bolus therapy in neonates with haemodynamic compromise.MethodsThis was a pragmatic, international, multicentre observational study in neonatal units across Australasia, Europe and North America with a predefined study period of 10–15 study days per participating neonatal unit between December 2015 and March 2017. Infants ≤28 days of age

Purpose: In addition to incisional hernia, inguinal hernia is a recognized complication to radical retropubic prostatectomy. To compare the risk of developing inguinal and incisional hernias after open radical prostatectomy compared to robot-assisted laparoscopic prostatectomy. Method: Patients planned for prostatectomy were enrolled in the prospective, controlled LAPPRO trial between September 20

Introduction: Whether data on International Classification of Diseases (ICD)-codes from the Swedish National Patient Register (NPR) correctly correspond to subtypes of inflammatory bowel disease (IBD) and phenotypes of the Montreal classification scheme among patients with prevalent disease is unknown.Materials and methods: We obtained information on IBD subtypes and phenotypes from the medical re

Extracorporeal photopheresis (ECP) is one of the most used and established therapies for steroid-refractory graft-vs-host disease (GvHD), with a good effect to side effect profile. In this review, we present a summary of present literature and provide evidence-based treatment guidelines for ECP in GvHD. The guidelines constitute a consensus statement formed by the Nordic ECP Quality Group represen

Wear particles originating from disc brakes contribute to particulate concentration in the urban atmosphere. In this work novel nanoporous composite-based and conventional brake materials were tested against cast-iron discs in a modified pin-on-disc machine. During testing airborne wear particles were measured online and collected on filters, which were analysed using SEM and EDX. The morphology o

Background and objectives: Fetal RHD genotyping of cell-free maternal plasma DNA from RhD negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment workshop with the participation of 31 laboratories. Materials and methods: Aliquots of

Plastics contribute the most to the ever-growing buildup of pollution in Earth’s water bodies. In the aquatic environment, plastic essentially exists in multiple forms before and following passage to nature depending on its synthetic pathway and succeeding degree of fragmentation or degradation, and includes bulk material, as well as nanosized particles. It is of utmost importance to understand th

The machinability of brass is considered to increase with the addition of lead as an alloying element. Due to both environmental and health reasons, the decrease of lead in brass components is of high importance. Several mechanical and thermal material properties control a materials machinability, in combination with the chosen machining system. To evaluate the difference in machinability between

Background: Health-related quality of life (HRQoL) has been reported for out-hospital (OHCA) and in-hospital cardiac arrest (IHCA) separately, but potential differences between the two groups are unknown. The aim of this study is therefore to describe and compare HRQoL in patients surviving OHCA and IHCA. Methods: Patients ≥18 years with Cerebral Performance Category 1–3 included in the Swedish Re

Airborne particulate emissions originating from the wear of pads and rotors of disc brakes contribute up to 50% of the total road emissions in Europe. The wear process that takes place on a mesoscopic length scale in the contact interfaces between the pads and rotors can be explained by the creation and destruction of contact plateaus. Due to this complex contact situation, it is hard to predict h

Airborne wear particles originating from disc brakes are among the main contributors to non-exhaust emissions. The macroscopic wear behaviour of disc brakes can be explained by the growth and destruction of mesoscopic contact plateaus. The pad wear and temperature has earlier been simulated using a cellular automaton mesoscopic approach. The present paper seeks to refine the simulation approach to

This article aims to contribute to the growing scholarly literature on the implementation of shariʿa-based family law codes by describing and analyzing the gender implications of religiously inspired judicial activism in relation to judicial divorce through khulʿ. The article highlights two functions played by family court judges and other legal professionals. First, I argue that Egyptian family c

BACKGROUND: Elderly patients with acute myocardial infarction undergoing percutaneous coronary intervention are at increased risk of both ischemic and bleeding complications. The optimal anticoagulation strategy in these patients is uncertain. Therefore, we compared bivalirudin to heparin monotherapy in a contemporary cohort of such patients. METHODS: A prespecified subgroup analysis of elderly pa

The behaviour and function of dynamic samples can be investigated using optical imaging approaches with high temporal resolution and multidimensional acquisition. Snapshot techniques have been developed in order to meet these demands, however they are often designed to study a specific parameter, such as spectral properties, limiting their applicability. Here we present and demonstrate a frequency

BACKGROUND: Adolescent depression is one of the largest health issues in the world and there is a pressing need for effective and accessible treatments. OBJECTIVE: This trial examines whether affect-focused internet-based psychodynamic therapy (IPDT) with therapist support is more effective than an internet-based supportive control condition on reducing depression in adolescents. METHODS: The tria

Carriers of the hydroxysteroid 17-β dehydrogenase 13 (HSD17B13) gene variant (rs72613567:TA) have a reduced risk of NASH and cirrhosis but not steatosis. We determined its effect on liver histology, lipidome, and transcriptome using ultra performance liquid chromatography-mass spectrometry and RNA-seq. In carriers and noncarriers of the gene variant, we also measured pathways of hepatic fatty acid

PURPOSE Most patients with early-stage breast cancer are treated with adjuvant radiotherapy (RT) after breast-conserving surgery (BCS) to prevent locoregional recurrence (LRR). However, no genomic tools are used currently to select the optimal RT strategy. METHODS We profiled the transcriptome of primary tumors on a clinical grade assay from the SweBCG91-RT trial, in which patients with node-negat