T cell recognition of the type II collagen (CII) 260-270 peptide is a bottleneck for the development of collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis. We have earlier made C3H.Q mice expressing CII with glutamic acid instead of aspartic acid at position 266 (the MMC-C3H.Q mouse), similar to the rat and human CII epitope, which increases binding to MHC class II and leads

Final results from the DELPHI Collaboration on the lifetime of B+ and B-0 mesons and the mean b-hadron lifetime, are presented using the data collected at the Z(0) peak in 1994 and 1995. Elaborate, inclusive, secondary vertexing methods have been employed to ensure a b-hadron reconstruction with good efficiency. To separate samples of B+ and B-0 mesons, high performance neural network techniques a

Specific language impairment has, although not without controversy, been considered as a consequence of a phonological memory deficit. Non-word repetition has been proposed as a reliable index of phonological memory and also as predictive of lexical and grammatical development in normally developing and language-impaired children. The main aim was to study the relationship between repetition of wo

We have measured the oscillator strength of the Ni I line at 6300.34Å, which is known to be blended with the forbidden line [O I]lambda6300 used for the determination of the oxygen abundance in coolstars. We also give wavelengths of the two isotopic line components of58Ni and 60Ni derived from the asymmetriclaboratory line profile. These two line components of Ni I have to beconsidered when calcul

The diagnostic terms hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are based on historical and overlapping clinical descriptions. Advances in understanding some of the causes of the syndrome now permit many patients to be classified according to etiology. The increased precision of a diagnosis based on causation is important for considering logical approaches to tre

Background Hip replacement as a routine procedure was introduced in Lithuania in 1991. At Klaipeda Hospital, one of the 2 hospitals at which this was begun, the arthroplasties were followed prospectively from the start. This study concerns the 10-year results from a country with no previous experience of hip replacement. The results are compared with those from a hospital with considerable experie

1. To improve mechanistic understanding of plankton responses to eutrophication, a mesocosm experiment was performed in the shallow littoral zone of a south Swedish lake, in which nutrient and fish gradients were crossed in a fully factorial design. 2. Food chain theory accurately predicted total biomass development of both phyto- and zooplankton. However, separating zooplankton and algae into fin

Differential scanning calorimetry (DSc) and dynamic light scattering (DLS) were used to obtain the gel to liquid-crystalline phase transition temperature (T-m) and the apparent hydrodynamic radius (R-h) of spontaneously formed cationic vesicles of dialkyldimethylammonium bromide salts (CnH2n+1)(2)(CH3)(2)N+center dot Br-, with varying chain lengths. The preparation of cationic vesicles from aqueou

An entirely new type of blood gas analyser has made its way into the marketplace, to be used, for example, in emergency rooms, intensive care units, ambulances, and bedside with quarantined patients in infectious diseases units. The instruments reviewed here employ new miniaturised analysis circuitry, integrated into the cassette on which the blood sample is applied. These instruments are designed

Early Ordovician (Late Arenig) limestones from the SW margin of Baltica (Scania-Bomholm) have multicomponent magnetic signatures, but high unblocking components predating folding, and the corresponding palaeomagnetic pole (latitude = 19degreesN, longitude = 051degreesE) compares well with Arenig reference poles from Baltica. Collectively, the Arenig poles demonstrate a midsoutherly latitudinal pos

Whereas uncoupling protein 1 (UCP-1) is clearly involved in thermogenesis, the role of UCP-2 is less clear. Using hybridization, cloning techniques and cDNA array analysis to identify inducible neuroprotective genes, we found that neuronal survival correlates with increased expression of Ucp2. In mice overexpressing human UCP-2, brain damage was diminished after experimental stroke and traumatic b

Popular Abstract in Swedish Utformningen av fattigvården och de arbetskrav man ställer på mottagarna har alltid varit kontroversiella frågor i socialpolitiken, såväl under fattig- och arbetshusens tidsålder under 1800-talet, som i nuvarande diskussioner om socialbidrag och aktivering av bidragstagarna. Den första delen av avhandlingen diskuterar begreppen fattigdom, marginalisering och social utesManagement of poor relief and work demands have been controversial questions in social policy during the workhouse era of the nineteenth century as well as in current discussions on social assistance and activation of recipients. The first part contains a discussion on the concepts of poverty, marginalisation, and social exclusion, and continues with an overview of activation policies for recipien

Transforming growth factor beta (TGF-beta) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-beta signaling in liver regeneration in vivo, the TGF-beta type II receptor gene (Tgfbr2) was selectively deleted in hepatocytes by crossing "floxed" Tgfbr2 conditional knockout mice with transgeni

Overheating is a paramount problem in residential buildings in hot-humid climates in China during summer. This study aims to deal with the overheating problem and the problem of poor air quality in dwellings. The main objective is to improve indoor thermal conditions by passive cooling approaches, climatisation techniques in buildings without auxiliary cooling from air conditioning equipment. A f

Syftet med projektet är att teoretiskt utreda två frågeställningar med direktlimmat trägolv på betongunderlag. Första frågeställningen är i vilka fall det behövs ett extra fuktskydd under trägolv från AB Gustaf Kährs, för att undvika skador orsakade av byggfukt i underlag av normal husbyggnadsbetong. Andra frågeställningen är vilken ekvivalent uttorkningstid som behövs för byggfuktfri betong innan