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Crystal to crystal transformation in soft ionic microgels : Kinetics and the role of local mechanical susceptibilities

We report confocal microscopy experiments of electric-field-driven crystal-crystal transformations in microgel colloids with varying particle softness. The transformation kinetics are well described by phenomenological nucleation and growth theory. Using a spatial projection formalism, we determine local susceptibilities to affine shear deformation and nonaffine defect formation in the parent crys

Continuity equation for the many-electron spectral function

Starting from the recently proposed dynamical exchange-correlation field framework, the equation of motion of the diagonal part of the many-electron Green function is derived, from which the spectral function can be obtained. The resulting equation of motion takes the form of the continuity equation of charge and current densities in electrodynamics with a source. An unknown quantity in this equat

Location of Retroperitoneal Lymph Node Metastases in Upper Tract Urothelial Carcinoma : Results from a Prospective Lymph Node Mapping Study

Background: There is limited information on the distribution of retroperitoneal lymph node metastases (LNMs) in upper tract urothelial carcinoma (UTUC). Objective: To investigate the location of LNMs in UTUC of the renal pelvis or proximal ureter and short-term complications after radical nephroureterectomy (RNU) with lymph node dissection (LND). Design, setting, and participants: This was a prosp

Association between classes and subclasses of polyphenol intake and 5-year body weight changes in the EPIC-PANACEA study

Objective: The aim of this study was to evaluate the associations among the intake of total polyphenols, polyphenol classes, and polyphenol subclasses and body weight change over 5 years. Methods: A total of 349,165 men and women aged 25 to 70 years were recruited in the Physical Activity, Nutrition, Alcohol, Cessation of Smoking, Eating Out of Home and Obesity (PANACEA) project of the European Pr

Post-compression of multi-millijoule picosecond pulses to few-cycles approaching the terawatt regime

Advancing ultrafast high-repetition-rate lasers to shortest pulse durations comprising only a few optical cycles while pushing their energy into the multi-millijoule regime opens a route toward terawatt-class peak powers at unprecedented average power. We explore this route via efficient post-compression of high-energy 1.2 ps pulses from an ytterbium InnoSlab laser to 9.6 fs duration using gas-fil

CFD Simulation of Biomass Combustion in an Industrial Circulating Fluidized Bed Furnace

In this study, a three-dimensional computational fluid dynamics (CFD) model is employed to investigate the hydrodynamic and combustion characteristics of biomass particles in an industrial-scale circulating fluidized bed (CFB) furnace. The CFD model considered here is based on the Eulerian-Lagrangian framework, the multi-phase particle-in-cell (MP-PIC) collision model, the coarse grain method (CGM

Characteristic Modes of Frequency-Selective Surfaces and Metasurfaces from S-Parameter Data

Characteristic modes of arbitrary 2-D periodic systems are analyzed using scattering parameter data. This approach bypasses the need for periodic integral equations and allows for characteristic modes to be computed from generic simulation or measurement data. Example calculations demonstrate the efficacy of the method through comparison against a periodic method of moments (MoM) formulation for a

COMMISSIONING PLAN OF THE IFMIF-DONES ACCELERATOR

IFMIF-DONES (International Fusion Materials Irradiation Facility- DEMO-Oriented Neutron Early Source) - a powerful neutron irradiation facility for studies and certification of materials to be used in fusion reactors - is planned as part of the European roadmap to fusion electricity. Its main goal will be to characterize and to qualify materials under irradiation in a neutron field similar to the

PRESERVING BRIGHT ELECTRON BEAMS : DISTORTED CSR KICKS

Short pulse, low emittance electron beams are necessary to drive bright FEL X-rays, for this reason it is important to preserve and limit emittance growth. The strong bunch compression required to achieve the short bunches, can lead to coherent synchrotron radiation (CSR)-induced emittance growth, and while there are some methods of CSR cancellation, these methods may be less effective when the CS

Development and validation of time-to-event models to predict metastatic recurrence of localized cutaneous melanoma

Background: The recent expansion of immunotherapy for stage IIB/IIC melanoma highlights a growing clinical need to identify patients at high risk of metastatic recurrence and, therefore, most likely to benefit from this therapeutic modality. Objective: To develop time-to-event risk prediction models for melanoma metastatic recurrence. Methods: Patients diagnosed with stage I/II primary cutaneous m

Kullabygden : Naturrikedom och kulturtradition

Kullaberg är Kullabygdens kännemärke, blickfånget där urberget reser sig mot öppen himmel och vidsträckt hav. Vid horisonten möts Öresund och Kattegatt. Detta stenmassiv har en geologi som går mångmiljoner år tillbaka. I skuggan av den väldiga klippformationen breder kulturlandskapet ut sig i all sin variationsrikedom. En jordbruksbygd, inbäddad i skog och äng, som vetter mot den kustnära buskvege

Cognitive Safety is Largely Ignored in Clinical Drug Trials : A Study of Registered Study Protocols

Background and Objective: The number of reports on suspected drug-induced memory impairment submitted to the US Food and Drug Administration increased 30-fold from 2000 to 2022. Drugs are the most common cause of reversible dementia. However, there is very little research on drug-induced cognitive impairment. The aim of this study was to investigate if and how an assessment of cognitive safety was

Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases

Little is known about the genetic determinants of medication use in preventing cardiometabolic diseases. Using the Finnish nationwide drug purchase registry with follow-up since 1995, we performed genome-wide association analyses of longitudinal patterns of medication use in hyperlipidemia, hypertension and type 2 diabetes in up to 193,933 individuals (55% women) in the FinnGen study. In meta-anal

The structure and dynamics of locust bean gum in aqueous solution

Locust bean gum (LBG) is an industrially important polysaccharide used widely in food, cosmetics, textiles, and biopharmaceutical applications, where understanding its solution behaviour is important for formulation design. To address this, we investigate the structure and dynamics of LBG in aqueous solution using steady state shear rheology, static light scattering (SLS), ultra-small-angle light

The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients : a systematic review

Purpose: Investigating the use of the EORTC bladder cancer (BC) modules by evaluating: (a) study contexts/designs; (b) languages/countries in which the modules were administered; (c) their acceptance by patients/investigators; and (d) their psychometric properties. Methods: A systematic review was performed with studies from 1998 until 20/10/2021 in five databases. Articles/conference abstracts us

Can non-participants in a follow-up be used to draw conclusions about incidences and prevalences in the full population invited at baseline? An investigation based on the Swedish MDC cohort

Background: Participants in epidemiological cohorts may not be representative of the full invited population, limiting the generalizability of prevalence and incidence estimates. We propose that this problem can be remedied by exploiting data on baseline participants who refused to participate in a re-examination, as such participants may be more similar to baseline non-participants than what base

Life's Essential 8 and Life's Simple 7 in Relation to Coronary Atherosclerosis : Results From the Population-Based SCAPIS Project

Objective: To examine the associations between the American Heart Association scores (“Life's Essential 8” [LE8] and “Life's Simple 7” [LS7]) and 2 subclinical coronary atherosclerosis indicators: coronary computed tomographic angiography (CCTA)-stenosis and coronary artery calcium (CAC). Patients and Methods: We included a population-based sample, aged 50 to 64 years, recruited between 2013 and 2

Associations of dietary patterns between age 9 and 24 months with risk of celiac disease autoimmunity and celiac disease among children at increased risk

Background: Higher gluten intake in childhood is associated with increased incidence of celiac disease autoimmunity (CDA) and celiac disease. It remains to be studied whether different dietary patterns independent of gluten intake contribute to the incidence. Objectives: This study aimed to explore associations of dietary patterns by age 2 y with risk of CDA and celiac disease in genetically susce