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Mapping of quick clay formations using geotechnical and geophysical methods

Quick clay has been involved in most serious, large clay slides in Sweden, Norway, and Canada. This paper describes geotechnical and geophysical methods that can be used to locate and map the extent of quick clay formations. Surface resistivity measurements and four different sounding methods have been tested. The results have been compared with sensitivities determined using fall-cone tests. The

Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial

Background Postoperative policies of "wait-and-see" and radiotherapy for low-grade glioma are poorly defined. A trial in the mid 1980s established the radiation dose. In 1986 the EORTC Radiotherapy and Brain Tumor Groups initiated a prospective trial to compare early radiotherapy with delayed radiotherapy. An interim analysis has been reported. We now present the long-term results. Methods After s

A physically motivated modification of the strain equivalence approach

A phenomenological thermodynamic approach used for describing elasto-plasticity coupled with isotropic damage is considered. Using this approach it was recently shown by the authors that certain unwanted features exist in the plasticity-induced damage theories. This paper gives a suggestion on how to solve these issues. Based on physical arguments a simple modification of the postulate of strain e

Antibody-based microarrays.

Antibody-based microarrays are a new powerful proteomic technology that can be used to generate rapid and detailed expression profiles of defined sets of protein analytes in complex samples as well as high-resolution portraits of entire proteomes. Miniaturized micro- and nanoarrays can be printed with numerous antibodies carrying the desired specificities. Multiplexed and ultra-sensitive assays, s

Is private consumption growth higher (lower) during periods of fiscal contractions (expansions)?

Case studies have claimed that private consumption growth is higher during fiscal contractions due to the very fact that government spending is cut. Indeed, neoclassical theory has this implication. This paper uses regression analysis of a panel of 19 OECD countries and shows that this is not true in general. On the contrary, contraction (expansion) periods experience lower (higher) private consum

Metal ion enhanced binding of amd3100 to asp-262 in the cxcr4 receptor.

The affinity of AMD3100, a symmetrical nonpeptide antagonist composed of two 1,4,8,11-tetraazacyclotetradecane (cyclam) rings connected through a 1,4-dimethylene(phenylene) linker to the CXCR4 chemokine receptor was increased 7, 36, and 50-fold, respectively, by incorporation of the following: Cu2+, Zn2+, or Ni2+ into the cyclam rings of the compound. The rank order of the transition metal ions co

Simulating vegetation cover dynamics with regards to long-term climatic variations in sub-arctic landscapes

Iceland is facing severe land degradation in many parts of the country. This study aims to increase the understanding of the complex interactions and interconnectivity between the critical factors that help maintain the land degradation processes in sub-arctic environments. A holistic approach in the form of a causal loop diagram (CLD) is applied for diagnosing the influencing factors. To further

The illness experiences of patients after a first time myocardial infarction

The purpose of this study was to investigate illness experiences of patients after a first myocardial infarction (MI), focusing on life situation and the recovery process over time. Thirty patients were interviewed within the first 3 days of hospitalisation, and again 17 weeks after discharge. The interviews were tape-recorded verbatim and the transcriptions were analysed and categorised using qua

Ordovician palaeogeography with new palaeomagnetic data from the Montagne Noire (Southern France)

A joint palaeomagnetic and Ar-40/Ar-39 study has been performed on two olistolithic blocks from the Cabrieres Wildflysch in the Montagne Noire region of the Massif Central in France. There, andesitic volcanic and volcaniclastic rocks of Llanvirn-Early Caradoc age (ca 470-458 Ma) occur. Despite extensive secondary alteration, destruction of the dominant magnetic mineral phase and Ar-40/Ar-39 whole

Intermittent versus continuous electronic monitoring in labour: a randomised study

OBJECTIVE: To compare the efficacy in detecting signs of fetal hypoxia in labour of intermittent (I-group) versus continuous (C-group) electronic fetal monitoring in women with low or moderate risk factors for fetal distress. DESIGN: A prospective, randomised study. SETTING: A tertiary referral centre. SUBJECTS: Four thousand and forty-four parturients at low risk for obstetric complications with

Sanderlings (Calidris alba) have a magnetic compass: Orientation experiments during spring migration in Iceland

The migratory orientation of sanderlings (Calidris alba) was investigated with cage experiments during the spring migration in southwest Iceland. Sanderlings were exposed to 90 degrees counterclockwise-shifted magnetic fields under both clear skies and natural overcast. Clear sky control tests resulted in a northerly mean direction, in agreement with predictions based on ringing recovery data and

X-linked agammaglobulinemia (XLA): A genetic tyrosine kinase (Btk) disease

X-linked agammaglobulinemia is a heritable immunodeficiency disease caused by a differentiation abnormality, resulting in the virtual absence of B lymphocytes and plasma cells, The affected gene encodes a cytoplasmic protein tyrosine kinase, Bruton's agammaglobulinemia tyrosine kinase, designated Btk, Btk and the other family members, Tec, Itk and Bmx, contain five regions, four of which are commo

Ethyl glucuronide discloses recent covert alcohol use not detected by standard testing in forensic psychiatric inpatients

Background: Considerable lives and money could be saved if one could detect early stages of lapsing/ relapsing behavior in addicted persons (e.g., in safety-sensitive workplaces) and could disclose harmful drinking in social drinkers. Due to the serious public health problem of alcohol use and abuse worldwide, markers of alcohol use have been sought. Both ethyl glucuronide (EtG) and phosphatidyl e

Identification and genetic fingerprinting of Brachyspira species

Six Brachyspira type and reference strains, and 14 well characterized porcine field isolates representing all recognised porcine Brachyspira spp. were compared by different molecular methods. Sequence analysis of the 16S rRNA and the nox genes, pulsed-field gel electrophoresis (PFGE) and randomly amplified polymorphic DNA (RAPD) were used in the study. In addition the isolates were analysed by fiv

Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C : use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C

Amyloidogenic proteins like cystatin C and prion proteins have been shown to form dimers by exchange of subdomains of the monomeric proteins. This process, called "three-dimensional domain swapping," has also been suggested to play a part in the generation of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic, and persons carrying the corresponding gene suffer fro

Synthesis and surface characteristics of CeTbO3+delta induced by femtosecond laser irradiation

This work describes the use of focused, high-intensity light from a Ti: sapphire laser that generates femtosecond pulses to irradiate mixture of CeO2 and Tb4O7 under ambient conditions. The prepared samples were investigated by means of X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and scanning electron microscope (SEM). XRD and XPS measurement results demonstrated that solid sol

Developing and testing a questionnaire to assess the quality of pain management in acute care in Sweden.

Pain management is an important indicator of the quality of patient care. The aim of this study was to develop and test a questionnaire to assess the quality of pain management in acute care in Sweden with emphasis on validity and reliability, as well as pain severity, interference with function, and patient participation. A descriptive cross-sectional study was conducted with consecutively select

Functional Characterization of Arabidopsis Calreticulin1a: Key Alleviator of the Endoplasmic Reticulum Stress

The chaperone calreticulin plays important roles in a variety of processes in the endoplasmic reticulum (ER) of animal cells, such as Ca2+ signaling and protein folding. Although the functions of calreticulin are well characterized in animals, only indirect evidence is available for plants. To increase our understanding of plant calreticulins we introduced one of the Arabidopsis isoforms, AtCRT1a,