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Simulations of the beam performance in the MAX-II electron storage ring

The beam performance of the MAX II storage ring is described by computer simulations. The dynamic aperture reduction due to chromaticity correcting multipoles, higher order multipoles in quadrupoles and dipoles, alignment errors and energy deviations is calculated. The future operation of the storage ring with insertion devices is discussed. The results show that the MAX II storage ring will opera

Rancidity development in oat during industrial processing

To improve the shelf-life of food products rich in lipids, it is important to minimize the lipid oxidation that occurs during processing, since this oxidation not only decreases shelf-life but also induces off-flavors. To evaluate the oxidation of lipids in the production of one β-glucan-rich and one protein-rich food supplement made from oats (Avena sativa), the neutral and polar lipid profile, h

Pro-oxidative activity of trout and bovine hemoglobin during digestion using a static in vitro gastrointestinal model

The degradation of trout and bovine hemoglobin (Hb) and their pro-oxidant activities in washed cod muscle mince (WCM) were studied using simple pH-shifts to simulate gastrointestinal (GI) conditions (pH 7 → 6 → 3 → 7), as well as full static in vitro GI digestion. Following gastric acidification to pH 6, metHb formation increased, especially for trout Hb. Subsequent acidification to pH 3 promoted

INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies

In vitro digestion studies often use animal digestive enzyme extracts as substitutes of human gastric and pancreatic secretions. Pancreatin from porcine origin is thus commonly used to provide relevant pancreatic enzymes such as proteases, amylase and lipase. Rabbit gastric extracts (RGE) have been recently introduced to provide gastric lipase in addition to pepsin. Before preparing simulated gast

Affinity precipitation of dehydrogenases

Affinity precipitation, a novel technique closely related to immunoprecipitation and affinity chromatography, has been evaluated in systems comprised of dehydrogenases and a bifunctional NAD derivative, Bis-NAD. Lactate dehydrogenase and glutamate dehydrogenase were easily precipitated whereas yeast alcohol dehydrogenase required the presence of salt to enhance the affinity precipitation. Liver al

Effect of storage conditions on lipid oxidation, nutrient loss and colour of dried seaweeds, Porphyra umbilicalis and Ulva fenestrata, subjected to different pretreatments

Here we evaluated the levels of lipid oxidation products, fatty acids, ascorbic acid and colour of Porphyra and Ulva after oven-drying at 40 °C, and during subsequent storage for ≥370 days under light, semi-light and dark conditions. Part of the seaweed was pre-soaked in freshwater or pre-coated with a whey protein mixture. Controls consisted of freeze-dried seaweeds. Throughout storage there was

Steroid transformation using magnetically immobilized Mycobacterium sp.

Mycobacterium sp. (NRRL-B 3683) has been immobilized by adhesion of magnetic materials of submicron size to the bacterial surface. Preparations based on laboratory-prepared magnetic oxide that had been derivatized with hydrophobic octyltrichlorosilane showed the best properties. The magnetically immobilized bacteria were used for side-chain degradation of cholesterol into androsta-1,4-diene-3,17-d

Magnetic aqueous two-phase separation: A new technique to increase rate of phase-separation, using dextran-ferrofluid or larger iron oxide particles

A new technique to speed up the phase separation of aqueous two-phase systems is described. The technique is based on the addition of magnetically susceptible additives (ferrofluids or iron oxide particles). In a magnetic field such additives will induce a faster phase separation. In one approach, dextran-stabilized ferrofluid was added to an aqueous two-phase system containing polyethylene glycol

Synthesis of mannose oligosaccharides via reversal of the α-mannosidase reaction

Three naturally occurring isomers of the disaccharideO-α-D-mannosyl-D-mannoside were synthesized by reversing the hydrolytic activity of jack bean α-mannosidase at 75°C in a very high concentration of mannose. Higher oligosaccharides were also obtained at the later stages of the reaction. The maximum total yield of disaccharides was 37% (w/w) based on the total amount of saccharides.

Analysis of visual and acoustic measures for self-evacuations in road tunnels using virtual reality

Emergency fire situations in tunnels can be especially dangerous when occurring in long underground or subsea tunnels, particularly when evacuation on foot is the only alternative. This paper presents the results from a study comparing different visual and acoustic measures to facilitate efficient and safe emergency evacuation and their effect on people's self-rescue behaviour in response to a tun

Tick chemosensation and implications for novel control strategies

Ticks pose a major threat to the health of humans and animals. The use of synthetic acaricides and repellents has raised the concerns of potential health and environmental risks and increasing resistance in ticks. This article highlights the importance of the research on tick chemosensation in developing novel control agents. It provides a review on our current understanding of tick chemosensory s

Collagen VI : Role in synaptic transmission and seizure-related excitability

Collagen VI (Col-VI) is an extracellular matrix protein primarily known for its bridging role in connective tissues that has been suggested to play a neuroprotective role. In the present study we report increased mRNA and protein expression of Col-VI in the hippocampus and cortex at a late stage of epileptogenesis in a post-status epilepticus (SE) model of epilepsy and in brain tissue from patient

Regenerative business strategies : A database and typology to inspire business experimentation towards sustainability

In a time marked by growing environmental and societal challenges, where multiple planetary boundaries are being crossed, the way we conduct business practices needs to be rethought. Regenerative business models offer a path towards a more responsible future by incorporating strategies that go beyond net zero and focus on actively restoring the natural and social systems they operate in, creating

Expanding the therapeutic potential of neuro(active)steroids : a promising strategy for hyperdopaminergic behavioral phenotypes

Imbalances in dopamine activity significantly contribute to the pathophysiology of several neuropsychiatric disorders, including addiction, ADHD, schizophrenia, impulse control disorders, and Parkinson's Disease. Neuro(active)steroids, comprising endogenous steroids that finely modulate neuronal activity, are considered crucial regulators of brain function and behavior, with implications in variou

New theory to explain the effect of lactose fines on the performance of adhesive mixtures for inhalation

A new theory for the dispersibility enhancing effect of excipient fines for adhesive mixtures for inhalation is presented in this paper, while at the same time the shortcomings of current hypotheses are discussed. The proposed mechanism, denoted the ‘viscoelastic damping effect’, states that the presence of fines particles acts to dampen the collisions between carrier particles during mixing. As a

Multi-dimensional hadron structure through the lens of gluon Wigner distribution

In this review, we present the current status of phenomenological research on constraining the multi-dimensional proton (and nucleus) structure at high energies through studies of the so-called gluon Wigner distributions. We provide a brief pedagogical introduction into the corresponding theoretical definitions and modelling of exclusive and diffractive scattering observables in terms of the Wigne

Short photoperiods end autumn migration in a naïve diurnal migrant

Many migratory animals use daylength, or photoperiod, to signal when to migrate and transition between annual phenological states. Whether animals use photoperiod as a temporal or spatial cue while migrating, however, requires additional empirical support. We used hatch-year dunnocks, Prunella modularis (a songbird), caught during their first migration in southern Sweden to elucidate whether migra