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Experimental and modelling study of laminar burning velocity of aqueous ethanol

Laminar burning velocities of ethanol-water-air mixtures have been determined using the heat flux method. Aqueous ethanol contained 0–40% of water by mole fraction. Laminar premixed flat flames were stabilized on a perforated burner under adiabatic conditions for the equivalence ratio range from 0.7 to 1.4. Burning velocity measurements were performed for the initial gas temperature of 358 K and a

The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development

MLL rearrangements are translocation mutations that cause both acute lymphoblastic leukemia and acute myeloid leukemia (AML). These translocations can occur as sole clonal driver mutations in infant leukemias, suggesting that fetal or neonatal hematopoietic progenitors may be exquisitely sensitive to transformation by MLL fusion proteins. To test this possibility, we used transgenic mice to induce

Prolongation of The Activation Time in Ischemic Myocardium is Associated with J-wave Generation in ECG and Ventricular Fibrillation

J-wave pattern has been recognized as an arrhythmic risk marker, particularly in myocardial infarction patients. Mechanisms underlying J-wave development in ischemia remain unknown. In myocardial infarction model, we evaluated activation time delay as a prerequisite of J-wave appearance and predictor of ventricular fibrillation. Body surface ECGs and myocardial unipolar electrograms were recorded

Essential genes shape cancer genomes through linear limitation of homozygous deletions

The landscape of somatic acquired deletions in cancer cells is shaped by positive and negative selection. Recurrent deletions typically target tumor suppressor, leading to positive selection. Simultaneously, loss of a nearby essential gene can lead to negative selection, and introduce latent vulnerabilities specific to cancer cells. Here we show that, under basic assumptions on positive and negati

Collaborative tourism-making : an interdisciplinary review of co-creation and a future research agenda

For some time, tourism researchers have sought to examine and theorise types of collaborative exchange and the characteristics of relational work in tourism. Different ontological and epistemological framings, and associated language games have contributed to a fragmented body of knowledge. In this paper, we argue that the new term ‘co-creation’ is part of this language game, and efforts to date h

Using X-ray tomoscopy to explore the dynamics of foaming metal

The complex flow of liquid metal in evolving metallic foams is still poorly understood due to difficulties in studying hot and opaque systems. We apply X-ray tomoscopy –the continuous acquisition of tomographic (3D) images– to clarify key dynamic phenomena in liquid aluminium foam such as nucleation and growth, bubble rearrangements, liquid retraction, coalescence and the rupture of films. Each ph

Non-voluntary service interaction from a service logic perspective : children and value co-creation

Public sector services are complex in relation to many private sector services. For example, public sector services contain non-voluntary service interaction. This area of practice has not been extensively researched to date. In this article, we explore and discuss service interaction in public non-voluntary services targeting children, in order to understand what elements go into value co-creatio

Familial Clustering, Second Primary Cancers and Causes of Death in Penile, Vulvar and Vaginal Cancers

Data on familial risks in penile and vulvar/vaginal cancers and in second primary cancers (SPCs) following these cancers are limited. We used the Swedish Family-Cancer Database from years 1958 through 2015 to identify 3641 penile and 8856 vulvar/vaginal cancers and to calculate relative risks (RRs) and 95% confidence intervals (CIs) for these cancers according to site-specific cancer in family mem

Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading

Outside of the photosynthetic machinery, high-valent manganese cofactors are rare in biology. It was proposed that a recently discovered subclass of ribonucleotide reductase (RNR), class Id, is dependent on a Mn2(IV,III) cofactor for catalysis. Class I RNRs consist of a substrate-binding component (NrdA) and a metal-containing radical-generating component (NrdB). Herein we utilize a combination of

Oxidation-reduction potential (ORP) as a tool for process monitoring of H2O2/LPMO assisted enzymatic hydrolysis of cellulose

Oxidation-reduction potential (ORP) is an environmental factor of importance in several biological conversion processes. Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative disruption of the cellulose chain in the presence of oxygen or hydrogen peroxide and increase enzymatic hydrolysis yields. However, the enzymes are also sensitive to oxidative damage and the level of oxidative agent

High-Fat Diet Enriched with Bilberry Modifies Colonic Mucus Dynamics and Restores Marked Alterations of Gut Microbiome in Rats

Scope: Emerging evidence suggests that high-fat diet (HFD) is associated with gut microbiome dysbiosis and related disorders. Bilberry is a prebiotic food component with known health benefits. Herein, the dynamics of the colonic mucus layer and microbiome during HFD and bilberry supplementation are addressed. Methods and results: The effects on colonic mucus thickness in vivo and gut microbiota co

Modes of Shopping Constituting a Local Street: A video-ethnography of shopping as a practice

In the last decades spatiotemporal manifestations of shopping are changed radically in conjunction with proliferation of car usage, internationalization of retail, and establishment of out-of-town malls. The social, cultural, and economic backgrounds of this axis alteration and its implication to the city life have been discussed thoroughly. However, the main empirical focus laid mostly on the mai

Implications of existing local (mal)adaptations for ecological forecasting under environmental change

Standing genetic variation represents a genetic load on population fitness but can also support a rapid response to short-term environmental change, and the greatest potential source of such standing genetic variation typically exists among locally adapted populations living along an environmental gradient. Here, we develop a spatially explicit simulation model to quantify the contribution of exis

In Situ Formation of Ge Nanoparticles by Annealing of Al-Ge-N Thin Films Followed by HAXPES and XRD

Ge nanoparticles embedded in thin films have attracted a lot of attention due to their promising optical and electronic properties that can be tuned by varying the particle size and choice of matrix material. In this study, Ge nanoparticle formation was investigated for Al-Ge-N based thin films by simultaneous measurements of HAXPES and grazing incidence XRD during in situ annealing in vacuum cond

A covariant formulation of finite plasticity with plasticity-induced evolution of anisotropy : Modeling, algorithmics, simulation, and comparison to experiments

Motivated by experimental findings on sheet-metal forming, this article concerns the modeling of evolving anisotropies in finite plasticity. A covariant formulation of plasticity is employed in conjunction with evolution equations for the structural tensors that characterize the symmetry group of the yield function. A specific model is implemented into a finite element code to simulate tension and

The electronic structure of ionic liquids based on the TFSI anion : A gas phase UPS and DFT study

The valence bands of [EMIM][TFSI], [DEME][TFSI] and [PYR1,4][TFSI] gas-phase ion pairs have been investigated using ultraviolet photoelectron spectroscopy (UPS). The photoelectron spectra are interpreted by using several density functional and ab initio calculation methods. Although the experimental vapor phase spectra are similar, the different calculation methods make different predictions about

Evidence for Mesoproterozoic collision, deep burial and rapid exhumation of garbenschiefer in the Namaqua Front, South Africa

Metamorphic provinces such as the ∼1 ​Ga Grenvillian, ∼400 ​Ma Caledonide and Triassic Qinling Provinces often contain rocks with high-pressure assemblages such as eclogites, which formed at mantle depths in subduction zones. These are evidence of the accretion of terranes by subduction of oceans and collision to form large tectonostratigraphic provinces. The Mesoproterozoic Namaqua-Natal Province

Design of kinetic models for assessment of critical aspects in bioprocess development : A case study of biohydrogen

The world faces major climate challenges and extensive efforts need to be taken to combat this issue. Replacing fossil-derived fuels and chemicals with renewables are one important step on the way. Hydrogen has a great potential as a renewable energy carrier for the transport sector and as a green chemical for the industry. Today, the production of hydrogen stems primarily from fossil resources. A

Neural-Network-Based Adaptive Control for Bilateral Teleoperation with Multiple Slaves under Round-Robin Scheduling Protocol

A neural-network-based adaptive control scheme is developed for bilateral teleoperation systems with single-master-multiple-slaves in the presence of dynamic uncertainties and communication constraint. Discrete-time data transmitting communication network with bandwidth limitation and time-varying communication delays is considered and the Round-Robin scheduling protocol is used to orchestrate the