Synthesis of glycosylated amino acids. Solid-phase assembly of T-cell immunogenic glycopeptides and fragments from HIV gp120
Synthetic glycopeptides are valuable tools for studies of the biological functions of protein-bound carbohydrates. Today glycopeptides are efficiently prepared by solid-phase synthesis according to the 9-fluorenylmethoxycarbonyl (Fmoc) protocol, provided that suitable glycosylated amino acids are available. In this thesis commercial or readily accessible carbohydrate 1,2-trans peracetates were us
