Search results
Filter
Filetype
Your search for "*" yielded 532238 hits
A genome wide scan for early onset primary hypertension in Scandinavians.
Resilience of a zooplankton community subjected to marine intrusion in a tropical coastal lagoon
One of the main disturbances on Imboassica Lagoon is the occasional artificial opening of its sand bar. Following two such events, two environmental gradients were observed. One was directly related to entry of marine water ( salinity gradient); and the other to a decrease in dilution of the nutrient load, because of water level reduction ( trophic status gradient). Two stations were sampled. At S
Exploring plant–microbe interactions using DNA microarrays
Dynamics of intersexual conflict over precopulatory mate guarding in two populations of the isopod Idotea baltica
Aggressiveness during intersexual conflicts is predicted to depend on its costs, the value of winning and the power asymmetry of the contestants, all of which may vary between populations. In the marine isopod Idotea baltica (Pallas) a conflict occurs as females resist the attempts by males to start precopulatory mate guarding. We analysed contest dynamics with respect to female maturity stage, th
Increased expression of endothelin ETB and angiotensin AT(1) receptors in peripheral resistance arteries of patients with suspected acute coronary syndrome
Patients who experience chest pain, in which ischemic heart disease has been ruled out, still have an increased risk of future ischemic cardiac events and premature death, possibly due to subclinical endothelial dysfunction. A feature of endothelial dysfunction is an increased expression of arterial vasoconstrictor endothelin (ET) and angiotensin (AT) receptors. Our aim was to investigate if the a
Computationally intensive multivariate statistics and relative frequency distributions in archaeology (with an application to the Early Epipaleolithic of the Levant)
Archaeologists seek to analyze patterns of similarity and difference among diverse kinds of assemblages that (1) vary in the number of specimens and (2) have been characterized by standard multi-category frequency distributions. Recent developments in computer simulation methods offer marked improvements in our ability to test statistical hypotheses about variation in relative taxonomic or typolog
Operational planning, re-planning and risk analysis for software releases
Software release planning takes place on strategic and operational levels. Strategic release planning aims at assigning features to subsequent releases such that technical, resource, risk and budget constraints are met. Operational release planning focuses on the realization of a single software release. Its purpose is to assign resources to feature development tasks such that total release durati
Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development
The Notch signaling pathway is involved in several lineage commitment and differentiation events. One of these is fate determination of the common lymphoid progenitor, promoting T-cell development at the expense of B-cell differentiation. It has been suggested that this process relies on Notch's ability to inhibit E proteins, which are crucial for early B-cell development. Here, we report that Not
The inflammatory mediator leukotriene D4 induces beta -catenin signaling and its association with anti-apoptotic Bcl-2 in intestinal epithelial cells.
Increased levels of the inflammatory mediator leukotriene D-4 (LTD4) are present at sites of inflammatory bowel disease, and such areas also exhibit an increased risk for subsequent cancer development. It is known that LTD4 affects the expression of many proteins that influence survival and proliferation of intestinal epithelial cells. We demonstrate here that after LTD4 exposure, beta-catenin tra
"Let's go for a walk!": identification and prioritisation of accessibility and safety measures involving elderly people in a residential area
By emphasising the involvement of elderly people in a project applying a mixed-method approach, the overriding objective of this study was to identify and prioritise concrete measures aimed at increasing accessibility and safety in the outdoor pedestrian environment within a residential area of a Swedish town. Measures generally given priority were: the separation of pedestrians/cyclists, lower sp
Population divergence of genetic (co)variance matrices in a subdivided plant species, Brassica cretica
The present study of Brassica cretica had two objectives. First, we compared estimates of population structure (Q(st)) for seven phenotypic characters with the corresponding measures for allozyme markers (F-st) to evaluate the supposition that genetic drift is a major determinant of the evolutionary history of this species. Secondly, we compared the genetic (co) variance (G) matrices of five popul
Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.
Islet adaptation to insulin resistance: mechanisms and implications for intervention.
Effects of pentoxifylline and its metabolites on platelet aggregation in whole blood from healthy humans.
It is known that pentoxifylline inhibits platelet aggregation in vitro, but the effects from pentoxifylline and its main metabolites: 3,7-dimetyl-1(5 hydroxyhexyl)xanthine (R-M1 and S-M1), 3,7-dimetyl -1(4-carboxybutyl)xanthine (M4), 3,7-dimetyl -1(3-carboxypropyl)xanthine (M5), on platelet aggregation in whole blood in vitro and in vivo have not been studied. We found that pentoxifylline, rac-M1,
Bendamustine in the Treatment of Chronic Lymphocytic Leukemia - Consistent Superiority Over Chlorambucil in Elderly Patients and Across Clinically Defined Risk Groups
The Danish effect on Swedish alcohol costs An analysis based on hospitalization data from southern Sweden.
This study investigated: (a) the cost and change in hospitalizations related to alcohol misuse for the healthcare sector and (b) the effect of distance to the border on alcohol-related hospitalization costs. The first objective was analyzed using descriptive statistics and the second using ordinary least squares regression on aggregated municipality data. The total cost decreased marginally during
Contraceptive use in women with bacterial vaginosis
PIP: To determine whether bacterial vaginosis (BV) is associated with use of specific contraceptive methods, 956 women from family planning and youth clinics at 3 Swedish hospitals were enrolled in a cohort study. 131 women had at least 3 of the 4 clinical signs of BV: a homogenous gray vaginal discharge, a vaginal pH of 4.7, a positive amine test, and the presence of "clue" cells. Age at first in
Validation of the General Motor Function Assessment Scale - an instrument for the elderly
Purpose. The purpose of this study was to test the General Motor Function Assessment Scale (GMF) for content and criterion validity in geriatric home-rehabilitation. Furthermore, the GMF was analysed with respect to sensitivity, distribution, and for floor and ceiling effects. Method. Content validity was explored by questionnaires circulated to ten experts in the field of geriatrics. Three assess