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Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion

Basic fibroblast growth factor (FGF-2) is involved in the development and maintenance of the nervous system. Exogenous administration of FGF-2 increased dopaminergic (DA) graft survival in different animal models of Parkinson's disease. To study the physiological function of the endogenous FGF-2 system, we analyzed the nigrostriatal system of mice lacking FGF-2, mice overexpressing FGF-2, and FGF-

Direct heterogeneous electron transfer reactions of Trametes hirsuta Laccase at bare and thiol-modified gold electrodes

Direct electron transfer reactions of high redox potential Trametes hirsuta laccase on bare and 15 different thiol-modified gold electrodes were studied using cyclic voltammetry and potentiometry: Well-pronounced Faradaic processes were obtained for the enzyme adsorbed on bare gold, whereas reproducible and stable electrochemistry was obtained only when 4-aminothiophenol was used for gold modifica

Demanding Values : Participation, empowerment, and NGOs in Bangladesh

Popular Abstract in Swedish Begreppen ‘participation’ och ‘empowerment’ är flitigt använda inom utvecklingsprojekt i tredje världen. Den betydelse som tillskrivs begreppen idag betonar en normativ tolkning, baserad på ett alternativt perspektiv på utveckling vilket innebär utgångspunkt från de människor utvecklingsprojeket berör snarare än västerländsk kunskap och expertis. Begreppen kräver detaljThe concepts participation and empowerment are frequently used in development projects in the third world. The meaning given to the concepts today signal a normative orientation, marking an alternative, people-centred approach to development. When used in development projects, the concepts demand detailed descriptions. They also demand project implementers, often local NGOs (non-government organis

Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation - A Randomized trial

Context Inpatients with nonvalvular atrial fibrillation, warfarin prevents ischemic stroke, but dose adjustment, coagulation monitoring, and bleeding limit its use. Objective To compare the efficacy of the oral direct thrombin inhibitor ximelagatran with warfarin for prevention of stroke and systemic embolism. Design, Setting, and Participants Double-blind, randomized, multicenter trial (20002001)

Endoscopic sphincterotomy for bile duct calculi: factors influencing the success rate. Hepato-Gastroenterol 1996; 43: 127-133.

BACKGROUND/AIMS: Endoscopic sphincterotomy is an established treatment of retained or recurrent common bile duct calculi after cholecystectomy and in the majority of patients with an intact gallbladder. In order to identify patients ultimately requiring additional endoscopic procedures or surgery, factors predictive of decreased endoscopic bile duct clearance were sought. MATERIAL AND METHODS: Bet

Risk of developing diabetes is inversely related to lung function: a population-based cohort study.

AimTo investigate whether reduced lung function is a risk factor for developing diabetes. MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) a

Use of a hydrocapillary dressing in the management of highly exuding ulcers; a comparative study

Objective: To evaluate the safety and performance of Alione Hydrocapillary dressing (Coloplast A/S) in the management of highly exuding chronic venous leg ulcers and compare it with two hydropolymer dressings, Tielle and Tielle Plus (Johnson & Johnson). Method: A comparative clinical trial was conducted on 97 patients with an ankle brachial pressure index ?0.8 and a highly exuding leg ulcer. U

Onset of breeding among Swedish Starlings Sturnus vulgaris in relation to spring temperature in 1981-2003

Both spring temperature and date of the first Starling Sturnus vulgaris egg were highly correlated between different study sites and weather stations in the southern half of Sweden. In southern Sweden, but not in northern Sweden, onset of breeding correlated strongly with spring temperature, particularly during the last ten days of April, the period that happens to coincide with the start of breed

Pathogenic paths? A time geographical approach in medical geography

Medical geography usually attempts to disentangle and explain the ecological and causal contexts of health, disease and environment by mapping spatial patterns of cases and potential pathogenic factors. However, many diseases are believed to show after long periods of latency , spanning years and even decades between initial exposure and clinical onset. In view of high spatial human mobility - in

Simulation and experimentation of a single-phase claw-pole motor

Purpose - The purpose of the paper is to evaluate theoretically and experimentally the static and dynamic characteristics of a single-phase claw-pole motor using soft magnetic composite (SMC) for the stator core. Design/methodology/approach - On the basis of the static characteristics, which are measured and obtained from a series of 3D FE magnetostatic solutions, the dynamic characteristics are s

Hole-burning techniques for isolation and study of individual hyperfine transitions in inhomogeneously broadened solids demonstrated in Pr3+: Y2SiO5

Due to their narrow homogeneous linewidths, rare-earth ions in inorganic crystals at low temperatures have recently been given considerable attention as test materials for experiments in coherent quantum optics. Because these narrow linewidth transitions have been buried in a wide inhomogeneous line, the scope of experiments that could be carried out in these materials has been limited. However, h

Testing an oral assessment guide during chemotherapy treatment in a Swedish care setting: a pilot study

Oral complications are common in patients with haematological malignancies who undergo chemotherapy treatment. A pilot study including 16 haematological patients was carried out to evaluate the oral status using an Oral Assessment Guide (OAG) and to test the reliability of the OAG. The oral assessments were made daily by registered nurses at a Department of Internal Medicine in Sweden. Once a week

Intrauterine growth restriction.

Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of