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Microfluidic flow splitter shape optimization for high throughput

Due to an increasing incidence rate, the need for new effective methods for diagnosing cancer are of high importance. Studies have shown that circulating tumor cells, CTCs, have great potential as a diagnostic biomarker. Acoustophoresis is a label free method, capable of separating CTCs from red blood cells in a blood sample. In theory, this would enable better CTC detection than the gold standard

How molecular diagnostics based on gene expressions can improve diagnostics in Sarcoma

Sarcoma, a rare and heterogeneous cancer type, present significant diagnostic challenges due to its numerous subtypes. Molecular diagnostics and machine learning models have emerged as promising tools to enhance sarcoma diagnosis. This study, conducted at Qlucore, aims to explore the usage of these new techniques in improving sarcoma diagnostics, with a specific focus on soft tissue sarcomas. The

Ett inverterat nöjesfält : kunskap, upplevelse och vara genom Google Maps användarrecensioner

This thesis attempts to show tangible ways in which commodification of experience expands into areas outside of direct commercial activity, in contemporary mind and society. The user reviews of Google Maps (URGM) regarding places that don't offer sales of goods and services are being studied empirically, through qualitative text analysis. Functional analysis is also used to study the functions

Finite Element Analysis of Structures at High Temperatures with Special Application to Plane Steel Beams and Frames

Nonlinear analysis of structures at high temperatures is studied. Both geometric and material nonlinearities are taken into account.Continuum mechanics relations are used to derive general finite element equations. An alternative formulation to Total Lagrangian (TL) and Updated Lagrangian (UL) formulations named Partially updated Lagrangian (PL) formulation i presented.An isotropic small strain co

Debatt: Utvecklingen av Kinas ekonomi - utmaningar och möjligheter för svenska företag

Kinas utveckling framöver har lika uppenbara som stora implikationer för svenska företag. Nu gäller det att anpassa sig till de föränderliga globala förutsättningarna för att säkerställa långsiktig framgång, skriver Björn Cappelin, biträdande chef, Nationellt kunskapscentrum om Kina, Tommy Shih, docent, Lunds universitet och Fredrik Sjöholm, professor och vd, Institutet för Näringslivsforskning (I

Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells

Glucocorticoid use is associated with steroid-induced diabetes mellitus and impaired pancreatic β-cell insulin secretion. Here, the glucocorticoid-mediated transcriptomic changes in human pancreatic islets and the human insulin-secreting EndoC-βH1 cells were investigated to uncover genes involved in β-cell steroid stress-response processes. Bioinformatics analysis revealed glucocorticoids to exert

Europeanization through Cultural Diplomacy

Europeanization is a complex process that involves adopting common European values, standards, policies, and practices across political, economic, and social aspects. However, the role of culture in this process is often overlooked, although it is crucial in promoting understanding and respect among different cultures and traditions within the EU. Culture also plays a significant role in the EU

Welfare within planetary limits: deep transformation requires holistic approaches

In January 2023, Anders Rhiger Hansen visited Lund University to talk to Max Koch about sustainable welfare, human needs, social inequality and a little bit about Bourdieu. The message from Max was clear: politicians need to drop the idea of green growth and instead define a safe and just operating space to determine what can be done within this space. His sociological approach combines Marxian an

Development of techniques to determine extracellular matrix alterations in acute and chronic lung diseases and bioengineered tissues

Acute and chronic lung diseases are a major cause of global mortality. While pharmacological approaches exist, no therapies are curative. The only option at end-stage disease is lung transplantation which is hampered by a chronic shortage of donor organs. Therefore, there is a high interest to develop alternative approaches to use regenerative medicine approaches to generate new lung tissue in the

Moraliska gränsdragningar i arbetet som spelutvecklare

Dataspelsbranschen beskrivs som både en kulturell näring och som en del av tech-industrin. De olika beskrivningarna ger skilda associationer och illustrerar branschens många sidor. Det är också illustrativt för arbetet som spelutvecklare, vilket ofta beskrivs som en skärningspunkt mellan såväl konstnärligt arbete och teknik, som mellan kultur och kommers. I ett pågående forskningsprojekt om spelut

Reactive silica fractions in coastal lagoon sediments from the northern Gulf of Mexico

Continental-margin sediments account for ~ 50% of the oceanic biogenic silica burial despite covering < 10% of its area. In Mississippi Sound, a coastal lagoon in the northern Gulf of Mexico (nGoM), we measured sediment biogenic silica at sites removed from major freshwater discharge sources using the traditional method and a method that has been modified for deltaic systems to quantify other reac

Bröderna Kia: En fallstudie av beslutet att bli spion.

Syftet med denna studie är att undersöka och få en djupare förståelse för varför Peyman Kia började spionera för främmande makt med hjälp av sin bror Payam. Materialet består av Stockholm tingsrätts dom, förundersökningsprotokoll bestående av Peyman och Payams förhör, vittnesförhör samt ytterligare ett förhörsprotokoll inför rättegången i Svea hovrätt. Utifrån en fallstudie med kvalitativ textanal

Ett enat Kina och ett splittrat NATO - En analys av Frankrike respektive USA's syn på Kinesiska intentioner

The situation in the South China Sea region is apparently tense and has been for a long time. However, the reactions of various world powers have been different in visible concern about escalation between two of the area's more central players, China and Taiwan. This work is based on Keren Yahri-Milo's theories and work on intentions and how perceptions of intentions from a state can vary

Undersökning av förpackningstyp & förpackningsmaterial för perfusionslösning vid njurtransplantation

The demand for kidney transplantation is growing while the number of donors continues to be insufficient, prolonging the process. Today’s method has a short time frame for carrying out the transplant, where the kidney must be taken out within 30-60 minutes after death. Due to lack of time and logistics, this often creates a major problem and inhibits transplantation. UGLK Science has developed a s

Förbättrad design av en tittlåda för att skatta hörsel hos yngre barn

In order for the central auditory organs and auditory cortex to develop correctly, auditory stimulation is required from an early age. Due to this, it is vital to identify children with a hearing impairment as quickly as possible. Apart from the screening performed on all newborns in Sweden, the most common test method is visual reinforcement audiometry, VRA. The visual reinforcement tools used to

Detektion av lateraliserad avvikande aktivitet i elektroencefalografi av minnesinkodning via auditivt stimulus

The aim of this study was to evaluate two methods of detecting a difference in activity between the two hemispheres of the brain when presented with stimulus during memory encoding. The difference intended to be detected was based on the lateralization of brain processing of sensory input, which was triggered by an auditory stimulus in one ear at a time. The methods that were used for detection, c

"Det lundomsusade Torup" - Ideologiska och globala perspektiv på ett skånskt godslandskap

In this essay an attempt is made to interpret the landscape at the Scanian estate Torup from two perspectives not commonly used in the study of postmedieval landscapes: the ideological rather than the economical-functional, and the global rather than the local. The landscape is studied through historical maps and images as well as through field observations made during walks in the landscape, and