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The immune microenvironment of colorectal cancer - Relationship with survival, sidedness, and pre-diagnostic anthropometry

Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis

Probiotics for intestinal decolonization of ESBL-producing enterobacteriaceae; a randomized, placebo-controlled clinical trial

OBJECTIVES: Infections with extended spectrum beta-lactamase (ESBL) producing Enterobacteriaceae (EPE) are a major healthcare concern. Our goal was to investigate whether a probiotic mixture could be used for eradication therapy in patients with prolonged intestinal EPE carriage.METHODS: We performed a randomized, placebo-controlled single blinded clinical superiority trial in the south of Sweden

More Power to the People: Electricity Adoption, Technological Change and Social Conflict

There is a wide-spread concern that technical change may spur social conflicts, especially if workers are replaced with machines. To empirically analyze whether job destruction drives protests, we study a historical example of a revolutionary new technology: the adoption of electricity. Focusing on the gradual roll-out of the Swedish electricity grid between 1900 and 1920 enables us to analyze 2,4

A latent core of dark traits explains individual differences in peacekeepers’ unethical attitudes and conduct

The influence of military members’ malevolent personality traits on their ethical attitudes and behaviors has been the subject of research for decades. We investigated the relationship between malevolent individual difference factors (Machiavellianism, narcissism, psychopathy, the dominance facet of social dominance orientation, and right-wing authoritarianism) and aspects of military ethics befor

Next of kin’s quality of life before and after implementation of a knowledge-based palliative care intervention in nursing homes

Purpose: The purpose of this study was to evaluate whether an educational palliative care intervention improved the quality of life for next of kin to older persons in nursing homes. Methods: Altogether, 90 next of kin in the intervention group and 105 next of kin in the control group were included. Data were collected using the WHOQOL-BREF questionnaire, answered before and 3 months after the int

Presbyvestibulopathy : Diagnostic criteria Consensus document of the classification committee of the Bárány Society

This paper describes the diagnostic criteria for presbyvestibulopathy (PVP) by the Classification Committee of the Bárány Society. PVP is defined as a chronic vestibular syndrome characterized by unsteadiness, gait disturbance, and/or recurrent falls in the presence of mild bilateral vestibular deficits, with findings on laboratory tests that are between normal values and thresholds established fo

Tillitsbaserad styrning och ledning : Ett ramverk

Tillitsbaserad styrning och ledning (TSL) är en samling metoder som syftar till att öka kvaliteten i offentligt finansierade tjänster genom att öka tilliten till brukare och brukarmötande yrkesgrupper. Dessa metoder har utvecklats som svar på en växande kritik mot utvecklingen i den offentligt finansierade välfärdssektorn under senare år, bland annat en växande administrativ börda, stelbenta struk

201Thallium SPECT; accuracy in astrocytoma diagnosis and treatment evaluation

The aims of the studies included in this thesis were:• to investigate the reliability of 201thallium single photon emission computed tomography (201Tl SPECT) for preoperative diagnosis and histological staging of malignant astrocytomas in comparison with CT; • to develop a method for quantification of cerebral thallium uptake, and to evaluate the quantitative measurement in comparison with CT, for

Symbolic connotations of animals at early Middle Helladic Asine : A comparative study of the animal bones from settlement and its graves

This paper is a contribution to the zooarchaeological research on animals or animal parts found in human graves during the Middle Bronze Age in Greece. The animal bones from the early Middle Helladic settlement (MH I-II, c. 2100-1800 BC) and contemporary burials at Asine are presented. The goal is to compare the animal bones from the settlement with those from the burials, in terms of species comp