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Experimental design trade-offs for gene regulatory network inference: An in silico study of the yeast Saccharomyces cerevisiae cell cycle
Time-series of high throughput gene sequencing data intended for gene regulatory network (GRN) inference are often short due to the high costs of sampling cell systems. Moreover, experimentalists lack a set of quantitative guidelines that prescribe the minimal number of samples required to infer a reliable GRN model. We study the temporal resolution of data vs. quality of GRN inference in order to
Linear Dynamic Network Reconstruction from Heterogeneous Datasets
This paper addresses reconstruction of linear dynamic networks from heterogeneous datasets. Those datasets consist of measurements from linear dynamical systems in multiple experiments subjected to different experimental conditions, e.g., changes/perturbations in parameters, disturbance or noise. A main assumption is that the Boolean structures of the underlying networks are the same in all experi
Material temporal work in artistic innovation: How Hilma af Klint powered time
This chapter explores the material temporal work involved in protecting a radical artistic innovation, conceived ahead of its time, from incomprehension and projecting it into the future in search of receptive audiences. Inspired by the trajectory and recent rediscovery of the pioneering abstract artist Hilma af Klint, we suggest that it is temporal agency (i.e. anticipating of and acting upon one
Moderate and stable pain reductions as a result of interdisciplinary pain rehabilitation—A cohort study from the Swedish quality registry for pain rehabilitation (SQRP)
Few studies have investigated the real-life outcomes of interdisciplinary multimodal pain rehabilitation programs (IMMRP) for chronic pain. This study has four aims: investigate effect sizes (ES); analyse correlation patterns of outcome changes; define a multivariate outcome measure; and investigate whether the clinical self-reported presentation pre-IMMRP predicts the multivariate outcome. To thi
Rättegångskostnadsansvar efter återkallelse av verkställighetsansökan : Analys av NJA 2023 s. 149 Förbudet från kommissionen
Uppdragsöverskridande och handläggningsfel som klandergrund. : Särskilt om inverkansrekvisitets betydelse vid klander av skiljedom
Negotiating and sustaining temporary organizing through affective practices
In this study I investigate how collaborative relations in temporary organizing are mobilized and aligned towards a creative vision using affective practices. Building on the current literature, I argue that affective relations are a central to understanding the tension ridden negotiations of collaborative relations in temporary organizing. I draw upon the notion of affective practices to conceptu
Adulthood weight changes, body mass index in youth, genetic susceptibility and risk of atrial fibrillation : a population-based cohort study
Background: Epidemiological evidence on weight change and atrial fibrillation (AF) remains limited and inconsistent. Previous studies on body mass index (BMI) in youth and AF rarely considered subsequent BMI. This study aimed to assess the associations of AF with weight change and BMI in youth, as well as modified effect by genetic susceptibility of AF. Methods: The study included 21,761 individua
Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity
CONTEXT: Cardiometabolic multimorbidity (CM) is an increasing public health concern. Previous observational studies have suggested inverse associations between coffee, tea, and caffeine intake and risks of individual cardiometabolic diseases; however, their associations with CM and related biological markers are unknown.METHODS: This prospective study involved 172 315 (for caffeine analysis) and 1
Big data, big problems: Why scientists should refrain from using Google Trends
Google Trends has for over a decade been used by researchers in medicine and the social sciences who want to use information about internet searches to gain new data and insights concerning medical and social issues. A similar tool by the same company, Google Flu Trends, was abolished by Google in 2015 due to serious problems with accuracy; raising larger questions about the quality of the data pr
The Hyper-Secret Danish Intelligence Culture – Making sense of the Recurring Intelligence Scandals in Denmark
Kommentar till 8 kap Om advokater rättegångsbalken,
Advokatetiska skäl som grund för en advokat att frånträda ett förtroendeuppdrag : Analys av NJA 2024 s. 69 I-II De advokatetiska skälen I och II
Foster Care on the Market - Social Workers' Feeling Rules and Actions in Conflict
This presentation focuses the emotional dilemmas of social workers who recruit and assess foster parents, in a context increasingly defined by market dynamics. Following privatization paralleled with increasing need for childcare, private and public actors today compete to contract potential foster parents in Sweden. For this paper, 43 interviews (with social workers and managers), 21 observation This presentation focuses the emotional dilemmas of social workers who recruit and assess foster parents, in a context increasingly defined by market dynamics. Following privatization paralleled with increasing need for childcare, private and public actors today compete to contract potential foster parents in Sweden. For this paper, 43 interviews (with social workers and managers), 21 observation
Glossary on Good Practices in the Field of Social Work
The Glossary on good practices in the field of social work and human mobility is the resultof the Global-ANSWER Network’s search for consensus on the conceptualisation and methodo-logy of social interventions with migrants and applicants for international protection. The aim isto bring together the key concepts around which this research project revolves, supported bythe interdisciplinary and inte
Towards alternative ecologies of encounter: crafting a vital materialist perspective of cultural entrepreneurship
In the wake of an aesthetic capitalism, the cultural and creative industries (CCI) have become a growing and thriving sector of Western and other economies. Cultural entrepreneurial processes propel the CCI and their regime of aesthetic innovation and constitute constantly evolving art worlds. My dissertation focuses on the material-affective dimensions of these art worlds. It explores cultural en