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Comparison of a 'freeze-all' strategy including GnRH agonist trigger versus a 'fresh transfer' strategy including hCG trigger in assisted reproductive technology (ART) : A study protocol for a randomised controlled trial

Introduction Pregnancy rates after frozen embryo transfer (FET) have improved in recent years and are now approaching or even exceeding those obtained after fresh embryo transfer. This is partly due to improved laboratory techniques, but may also be caused by a more physiological hormonal and endometrial environment in FET cycles. Furthermore, the risk of ovarian hyperstimulation syndrome is pract

Maggot Secretions Skew Monocyte-Macrophage Differentiation Away from a Pro-Inflammatory to a Pro-Angiogenic Type

Background: Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. Earlier we reported maggot secretions to inhibit pro-inflammatory responses of human monocytes. The aim of this study was to investigate the effect of maggot secretions on the differentiation of monocytes into pro-inflammatory (MØ-1) and anti-inflammatory/pro-angiogenic macrophages (MØ-2) as these cel

Maggot excretions/secretions inhibit multiple neutrophil pro-inflammatory responses

There is renewed interest in the use of maggots (Lucilia sericata) to aid in healing of chronic wounds. In such wounds neutrophils precipitate tissue damage rather than contribute to healing. As the molecules responsible for the beneficial actions of maggots are contained in their excretions/secretions (ES), we assessed the effects of ES on functional activities of human neutrophils. ES dose-depen

Sourcing Trends Predictions - An Analysis of Regions and Strategies

This paper aims to highlight historical trends regarding information systems (IS) sourcing, as well as glimpsing into the subject's future. Depending on economic growth, industrialization and changes in the political climate, certain countries have become either less or more attractive as destination countries for IS sourcing. As outsourcing strategies becomes more mature, especially in the IS sec

Airborne particles in indoor environment of homes, schools, offices and aged care facilities : The main routes of exposure

It has been shown that the exposure to airborne particulate matter is one of the most significant environmental risks people face. Since indoor environment is where people spend the majority of time, in order to protect against this risk, the origin of the particles needs to be understood: do they come from indoor, outdoor sources or both? Further, this question needs to be answered separately for

A community proposal to integrate proteomics activities in ELIXIR

Computational approaches have been major drivers behind the progress of proteomics in recent years. The aim of this white paper is to provide a framework for integrating computational proteomics into ELIXIR in the near future, and thus to broaden the portfolio of omics technologies supported by this European distributed infrastructure. This white paper is the direct result of a strategy meeting on

Expectations of Qigong and Exercise Therapy in Patients With Long-term Neck Pain: An Analysis of a Prospective Randomized Study.

ObjectiveThe aim of the present study was to study differences in treatment expectations after participating in qigong and exercise therapy among participants with long-term neck pain, the impact of total group expectations on treatment outcomes, and the relationship between these treatment expectations and pain and disability.MethodReliable questionnaires were used. Differences between qigong and

Increased carotid artery lesion inflammation upon treatment with the CD137 agonistic antibody 2A

Background: Increased inflammatory activity destabilizes the atherosclerotic lesion and may lead to atherothrombosis and symptomatic cardiovascular disease. Co-stimulatory molecules, such as CD137, are key regulators of inflammation, and CD137 activity regulates inflammation in experimental atherosclerosis. Here, we hypothesized that CD137 activation promotes carotid artery inflammation and athero

Authors and Authoritarianism in Central Asia : Failed Agency and Nationalising Authoritarianism in Uzbekistan and Kazakhstan

This paper aims to reconstruct widely accepted concepts of the top-down authoritarian nature of Central Asian politics in Kazakhstan and Uzbekistan through a comparative study of the pro-democratic movements that emerged in the late 1980s. By analysing data from interviews with the cultural elites of the late Soviet perestroika period and data on the indigenous nationalist movements such as Erk, Z

Some short advice to a PhD-student

Ett 20-tal korta råd till en doktorand om konsten att skriva en avhandling.Around 20 different short advice about the art of writing a doctoral thesis

Vitamin K and its Role in Diabetic Vascular Complications and Low-Grade Inflammation

This review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in typeThis review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in type

Ormen och Stormguden

Swedish translation from Hittite, with introduction and commentary, of the myth of Illuyanka.