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Impacts and responsibilities for sustainable tourism: a tour operator's perspective

Tourism is currently responsible for the largest, annual human migration in history. This great movement of people has significant positive and negative consequences on nature, societies, cultures and economies. Desired worldwide for its economic benefits, tourism is anticipated to double during the next 20 years, and the multiple consequences of such rapid growth,,call for a preventative approach

Automated flow enzyme-linked immunosorbent assay (ELISA) system for analysis of methyl parathion

sensitive detection of pesticides is of utmost importance in environment pesticides in agricultural and environmental samples wherein antibodies are employed against the target molecules. Accurate diagnosis depends on the affinity and specificity of the antibody preparation used, and high affinity antibodies are essential for the detection of very small amounts of pesticides. Enzyme linked immuno

A Market-driven Requirements Engineering Process - Results from an Industrial Improvement Programme

In market-driven software evolution, the objectives of a requirements engineering process include the envisioning and fostering of new requirements on existing packaged software products in a way that ensures competitiveness in the market place. This paper describes an industrial, market-driven requirements engineering process which incorporates continuous requirements elicitation and prioritisati

Mechanism of NADH transfer among dehydrogenases

Steady-state and transient-state kinetic experiments have been performed to test the proposal that there is a direct (channelled) transfer of NADH from one dehydrogenase to another if the two enzymes exhibit distinct chiral coenzyme specificity (A-side vs. B-side). The results lend no support to this proposal, but are fully consistent with a free-diffusion mechanism of NADH transfer irrespective o

Cataract surgery and quality of life in patients with age related macular degeneration.

Background: The coexistence of cataract and age related macular degeneration (AMD) is not unusual, especially in the very elderly. The outcome of cataract surgery in these cases depends on the effect of AMD on vision. In this study the authors have compared the outcome of cataract patients with AMD to that of cataract patients with no vision threatening ocular comorbidity, and analysed possible pr

Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG-expansion in the gene encoding the protein huntingtin. The disease is characterized by progressive motor disturbances, cognitive defects, dementia, and weight loss. Using western blotting and immunohistochemistry we have assessed the expression levels and patterns of a number of proteins involved in neuro

Weakly bound s(1/2) neutrons in the many-body pair correlation of neutron drip line nuclei

With a simplified model in the Hartree-Fock-Bogoliubov (HFB) approximation, the behavior of weakly bound s(1/2) neutrons in the many-body pair correlation is studied by solving the HFB equation in coordinate space with the correct asymptotic boundary conditions. It is shown that in one-neutron pickup reactions on the even-even neutron-drip-line nuclei, which contain loosely bound s(1/2) neutrons,

Tail current noise suppression in RF CMOS VCOs

This paper presents the experimental results of two different techniques, inductive degeneration and capacitive filtering, for reducing the phase noise in tail-biased RF CMOS voltage-controlled oscillators (VCOs). Both techniques prevent the low-frequency tail current noise from being converted into phase noise. The techniques are applied to two distinct VCO designs, showing that the largest phase

Formation of ferroelectric domains observed in simulation of droplets of dipolar particles

In this work it is shown that domains of ordered dipoles are formed in large droplets made from dipolar particles provided that the dipole-dipole interaction between nearest neighbors is larger than the thermal energy. The size of the domains grows almost linearly with the size of the droplets for droplets containing 1000-30 000 particles. The largest domains occupy around 25-35% of the droplet vo

One size fits all?: Towards a differentiated regional innovation policy approach

Innovation has moved to the foreground in regional policy in the last decade. Concrete policies were shaped by “best practice models” derived from high-tech areas and well performing regions. These are often applied in a similar way across many types of regions. Here an attempt is made to show that there is no “ideal model” for innovation policy as innovation activities differ strongly between cen

Electronic structure of quantum dots

The properties of quasi-two-dimensional semiconductor quantum dots are reviewed. Experimental techniques for measuring the electronic shell structure and the effect of magnetic fields are briefly described. The electronic structure is analyzed in terms of simple single-particle models, density-functional theory, and "exact" diagonalization methods. The spontaneous magnetization due to Hund's rule,

Kontrastnefropati efter datortomografi. Hydrering och anpassad kontrastmedelsdos ger bästa profylax

Nefrotoxicitet efter kontrastmedelstillförsel, räknat som en 25-procentig stegring av kreatinin i plasma, förekom hos 12 procent i en oselekterad grupp patienter som genomgått datortomografi. Generell arterioskleros kan läggas till övriga kända riskfaktorer för utveckling av kontrastmedelsnefrotoxicitet. Uppskattning av njurfunktion, t ex med hjälp av lämplig formel, bör göras före kontrastmedelst

Spin transmission through quantum dots with strong spin-orbit interaction

Quantum oscillations of the spin conductance through regular and chaotic 2D quantum dots under the varying Rashba spin-orbit interaction and at zero magnetic field have been investigated numerically by summing up the spin evolution matrices for classical transmitting trajectories. The Fourier analysis of these oscillations indicates a strong geometry dependence of the power spectra. The spectra fo