Aims Hypertrophic cardiomyopathy (HCM) is the commonest inherited cause of sudden cardiac death in children; current guidelines suggest HCM screening after 12-15 years of age. The study aims to establish the age range at highest risk. Methods and results Cohort study from six regional centres of paediatric cardiology, including children presenting with sudden death; n = 150 (59% = male; 39% famili

Simple surrogate fuels are needed to model practical fuels, which are complex mixtures of hydrocarbons. The surrogate fuel should match the combustion and emissions behaviour of the target fuel as much as possible. This paper presents experimental results using a wide range of fuels in both the gasoline and diesel auto-ignition range, but of different volatilities and compositions, in a single cyl

Background: The benefits of exercise in mild and moderate knee or hip osteoarthritis (OA) are apparent, but the evidence in severe OA is less clear. We recently reported that neuromuscular training was well tolerated and feasible in patients with severe primary hip or knee OA. The aims of this controlled before-and-after study were to compare baseline status to an age-matched population-based refe

Popular Abstract in Swedish Det finns övertygande bevis för att fysisk inaktivitet ökar såväl sjuklighet som dödlighet när det gäller flertalet av våra vanligaste folksjukdomar. Inaktivitet är den globalt sett fjärde största riskfaktorn och orsak till förtida död, efter högt blodtryck, tobak och högt blodsocker. Enligt WHO:s beräkningar uppgår antalet dödsfall i världen orsakat av inaktivitet tillThe overall aim of this thesis was to estimate health economic consequences of the four-month primary care program ”Physical Activity on Prescription (PAP)”. Inactivity means a highly increased independent risk factor for public health diseases and morbidity, and is an economic burden to society. Evidence for cost effective interventions aiming at increasing physical activity (PA) level among inac

Syftet med denna studie är att analysera hur personal inom socialtjänsten tolkar, definierar och upplever ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur den intervjuade och observerade personalen uppfattar och kategoriserar de inom projektet anställda samordnarna. De anställda inom socialtjänsten upplever att projektet kommit The aim of this study is to analyze how the Social Services personnel interpret, define and perceive, on the one hand, the project “Motverka Våld och Gäng” meaning “Counteract Violence and Gangs”, and on the other hand the role of the Coordinators employed in this project. Heads of units and Social Secretarys were interviewed, as well as observed and recorded at meetings. The personnel of the Soc

Measurements of direct photon production in p + Pb and p + C collisions at root(NN)-N-s = 17.4 GeV are presented. Upper limits on the direct photon yield as a function of p(T) are derived and compared to the results for Pb + Pb collisions at root(NN)-N-s = 17.3 GeV. The production of the eta meson, which is an important input to the direct photon signal extraction, has been determined in the eta -

The influence on ultrafast demagnetization dynamics of metallic nano-structured gratings deposited on thin films of magnetic Co/Pt multilayers is investigated by the time-resolved optical Kerr effect. Depending on the polarization of the pump pulse, a pronounced enhancement of the demagnetization amplitude is found. Calculation of the inhomogeneous optical field distribution due to plasmon interac

Context. Kinematical data such as the mean velocities and velocity dispersions of stellar samples are useful tools to study galactic structure and evolution. However, observational data are often incomplete (e. g., lacking the radial component of the motion) and may have significant observational errors. For example, the majority of faint stars observed with Gaia will not have their radial velocit

Fms-like tyrosine kinase 3 (Flt3) is an important growth factor receptor in hematopoiesis. Gain-of-function mutations of the receptor contribute to the transformation of acute myeloid leukemia (AML). Src-like adaptor protein (SLAP) is an interaction partner of the E3 ubiquitin ligase Cbl that can regulate receptor tyrosine kinases-mediated signal transduction. In this study, we analyzed the role o

Asteroids and Kuiper belt objects are remnant planetesimals from the epoch of planet formation. The first stage of planet formation is the accumulation of dust and ice grains into mm-cm-sized pebbles. These pebbles can clump together through the streaming instability and form gravitationally bound pebble `clouds'. Pebbles inside such a cloud will undergo mutual collisions, dissipating energy into

The fact that men and women are living longer than they have ever done before is something in which we can all rejoice. However, the process of ageing is associated with changes in skeletal, muscular, gastrointestinal, neural hormonal and metabolic processes that seriously affect an individual's performance and quality of life. Indeed, Such changes can be contributory to a loss of independence in

The possibility of improving the physical quality of extruded fish feed using transglutaminase (TGase) treatment at different stages of the production process was investigated. The addition of TGase to the raw material mix and processing under high and medium moisture conditions significantly increased (p > 0.05) the durability, hardness and elasticity of fish feed pellets. However, the water stab

Energy use and supply are evident issues to consider for a sustainable development, where the economic, social and environmental aspects are all important. In large grid-bound systems, the supply of energy is usually a rather invisible activity and the contacts between household custo-mers and utilities are sometimes only repre-sented through the energy bill. In this thesis, three particular field

Purpose To investigate the association between maternal use of antihypertensives in early pregnancy and delivery outcome, notably infant congenital malformations. Methods A cohort study of 1,418 women who had used antihypertensive drugs in early pregnancy but had no diabetes diagnosis were identified from the Swedish Medical Birth Register. Results There was an excess risk for placental abruption,

Conclusive English 'then' and Swedish 'då' are compared on the basis of a bi-directional translation corpus. The examples are classified into five different uses according to certain formal and contextual criteria. The two words are shown to have obvious functional similarities: in each of the categories distinguished 'then' and 'då' are the preferred translation equivalents of each other. But the

BACKGROUND: In a recent US cohort study, total coffee and tea consumption was inversely associated with risk of glioma, and experimental studies showed that caffeine can slow the invasive growth of glioblastoma. OBJECTIVE: The objective was to examine the relation between coffee and tea intake and the risk of glioma and meningioma in a large European cohort study, the European Prospective Investig