Search results

Filter

Filetype

Your search for "*" yielded 530256 hits

Tång + Keramik + Textil

Projektet undersöker och problematiserar tångens roll genom dess uttryck och materialitet. Projektet utforskar mötet mellan uttryck och upplevelser av tången utifrån ingångar som lera, akvarell och textila sublimerings- och transfertekniker, samt genom inkomna svar på frågelistan LUF 260 ”Tång och alger på marina marknader” (Lunds universitets folklivsarkiv). Formundersökningarna tar in sågtång oc

Periphilin self-association underpins epigenetic silencing by the HUSH complex

Transcription of integrated DNA from viruses or transposable elements is tightly regulated to prevent pathogenesis. The Human Silencing Hub (HUSH), composed of Periphilin, TASOR and MPP8, silences transcriptionally active viral and endogenous transgenes. HUSH recruits effectors that alter the epigenetic landscape and chromatin structure, but how HUSH recognizes target loci and represses their expr

The future of clinical trials for Alzheimer's disease. A blood-based biomarker perspective

Objectives: The primary objective was to investigate the utility of blood-basedbiomarkers of amyloid, tau, and neurodegeneration for (i) screening, (ii)enrichment, and (iii) tracking response to treatment in clinical trials of Alzheimer’sdisease.Methods: Longitudinal, participant-level data used in these studies was drawn fromthe Swedish BioFINDER study and the ADNI study. Participants were classi

Understanding, mapping and reporting of climate-related risks among listed firms in Sweden

We study the mapping and reporting of climate-related risks among firms listed on the NasdaqOMX stock exchange in Stockholm in four goods producing industries. Our study contains two parts: i) a study of the firms’ external communication through their annual reports, sustainability reports and webpages, and ii) a follow-up survey to the top management team. The survey contains quantitative questioWe study the mapping and reporting of climate-related risks among firms listed on the NasdaqOMX stock exchange in Stockholm in four goods-producing industries. Our study contains two parts: (i) a study of the firms’ external communication through their annual reports, sustainability reports and webpages, and (ii) a follow-up survey of the top management team. The survey contains quantitative quest

Divorce in the family: transmission of divorce across three generations

It is well-documented that there is an intergenerational transmission of divorce from parents to their children. This paper investigates how this transmission is affected by grandparents’ divorce. Using individual-level longitudinal data on marriages and divorces in Sweden, 1905–2015, I show grandparents’ divorce matters for their grandchildren’s divorce risks, even when parents remain married. Mo

Can a technology turn (also) into a symbol? The 3D printers case

The 3D printing industry has been recently affected by two events: the fact that open source (OS) business models are getting momentum, and the widespread diffusion of the Maker Movement. We argue that 3D printers can be conceptualised as innovations which embody both technological and symbolic aspects. If innovations of the first type are solely adopted for their technical utility, innovations wh

Word prominence ratings in Swedish television news readings : Effects of pitch accents and head movements

Prosodic prominence is a multimodal phenomenon where pitch accents are frequently aligned with visible movements by the hands, head, or eyebrows. However, little is known about how such movements function as visible prominence cues in multimodal speech perception with most previous studies being restricted to experimental settings. In this study, we are piloting the acquisition of multimodal promi

Inhibitory effect of UDP-glucose on cAMP generation and insulin secretion

Type-2 diabetes (T2D) is a global disease caused by the inability of pancreatic β-cells to secrete adequate insulin. However, the molecular mechanisms underlying the failure of β-cells to respond to glucose in T2D remains unknown. Here, we investigated the relative contribution of UDP-glucose (UDP-G), a P2Y14-specific agonist, in the regulation of insulin release using human isolated pancreatic is

In-gas-cell laser resonance ionization spectroscopy of Ir 196,197,198

Hyperfine structure (HFS) measurements of neutron-rich iridium isotopes Ir196,197,198 (Z=77,N=119-121) were performed via in-gas-cell laser resonance ionization spectroscopy at the KEK Isotope Separation System. Magnetic dipole moments μ and isotope shifts were determined from the HFS spectra. The variation of mean-square charge radii and quadrupole deformation parameters of these isotopes were ev

Direct Observation of a Plasmon-Induced Hot Electron Flow in a Multimetallic Nanostructure

Plasmon hot carriers are interesting for photoredox chemical synthesis but their direct utilization is limited by their ultrafast thermalization. Therefore, they are often transferred to suitable accepting materials that expedite their lifetime. Solid-state photocatalysts are technologically more suitable than their molecular counterparts, but their photophysical processes are harder to follow due

Improved soil hydrological modeling with the implementation of salt-induced freezing point depression in CoupModel : Model calibration and validation

Soil freezing/thawing is an important mechanism to control soil water and heat redistribution in mid-to-high latitudes. Salt in the agricultural soil from mid-to-high latitudes can alter characteristics of soil freezing/thawing cycle and then affect soil thermal and hydrological processes in winter and finally cause salinization in spring. To quantify the impacts of soil salinization on soil water

Contractual Learning and The Development of Heterogeneous Contracting Capabilities

Previous research suggests that parties in contractual relationships adopt a governance structure that economizes on transaction costs, and then over time learn to govern the contractual relationships in a more efficient manner by incrementally aligning contractual terms with transaction attributes based on new experiences made in the relationship. This implies that learning to contract and the de

Possible Relationship between the HLA-DRA1 Intron Haplotype of Three Single-Nucleotide Polymorphisms in Intron 1 of the HLA-DRA1 Gene and Autoantibodies in Children at Increased Genetic Risk for Autoimmune Type 1 Diabetes

Recently, a haplotype of three single-nucleotide polymorphisms (tri-SNP) in intron 1 of the HLA-DRA1 gene was found to be strongly associated with type 1 diabetes risk in HLA-DR3/3 individuals. The tri-SNP reportedly function as “expression quantitative trait loci,” modulating HLA-DR and -DQ expression. The aim was to investigate HLA-DRA1 tri-SNPs in relation to extended HLA class II haplotypes an

High expression of CD34 and α6-integrin contributes to the cancer-initiating cell behaviour in ultraviolet-induced mouse skin squamous cell carcinoma

Squamous cell carcinoma caused by ultraviolet light exposure represents over 40% of all malignant diseases. It is one of the most commonly found human tumours. Tumour mass within squamous cell carcinoma consists of various cell types, including cancer-initiating cells that are responsible for tumour progression, metastasis and chemoresistance and implicated in clinical relapse. In the present stud

Rasch analysis of the EQ-5D-3L and the EQ-5D-5L in persons with back and neck pain receiving physiotherapy in a primary care context

Aim: The purpose of this study was to investigate the psychometric properties of the EQ-5D-3L and the EQ-5D-5L in patients with back and neck pain. Materials and methods: Participants from two independent clinical survey studies was included in this study. In total 164 participants were answering either the EQ-5D-3L or the EQ-5D-5L after their visit to a physiotherapist in primary care for back an

Tau PET Imaging in Neurodegenerative Disorders

The advent of PET ligands that bind tau pathology has enabled the quantification and visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong evidence from neuropathologic studies that the most widely used tau PET tracers (i.e., 18F-flortaucipir, 18F-MK6240, 18F-RO948, and 18F-PI2620) bind tau aggregates formed in AD in the more advanced (i.e., ≥IV) Braak stages. Howe