The relative contribution of transcytosis vs. large pore transport to the passage of macromolecules across microvascular endothelia has been a controversial issue for nearly half a century. To separate transcytosis from 'porous' transport, the transcytosis inhibitors N-ethylmaleimide (NEM) and filipin have been tested in in situ or ex vivo perfused organs with highly conflicting results. In contin

This report is to be used as a guide in determining what an initial fire will look like. It is a summary of a large number of full scale tests on different items and under various conditions performed at different laboratories. The results shown are primarily the rate of heat release (RHR), as well as the production of smoke and generation of carbon monoxide. The results are shown as curves in thi

Antigenic variation in microbial surface proteins represents an apparent paradox, because the variable region must retain an important function, while exhibiting extensive immunological variability. We studied this problem for a group of streptococcal M proteins in which the similar to 50-residue hypervariable regions (HVRs) show essentially no residue identity but nevertheless bind the same ligan

I rapporten redovisas mätningar av energianvändningen i flerbostadshus. Mätningar gjordes under fyra eldningssäsonger. Med åtgärder som fönstertätning, inreglering av radiator- och ventilationssystem m m erhölls energibesparingar om 9-21% i förhållande till första säsongens mätning utan åtgärder.

Inclusive D*(+/-) production is measured in deep-inelastic ep scattering at HERA with the H1 detector. In addition, the production of dijets in events with a D*(+/-) meson is investigated. The analysis covers values of photon virtuality 2

The aim of this study was to determine the threshold of fracture probability at which interventions become cost-effective. We modeled the effects of a treatment costing $500/year, given for 5 years, that decreased the risk of all osteoporotic fractures by 35%, followed by a waning of effect for 5 years. Sensitivity analyses included a range of effectiveness (10%-50%) and a range of intervention co

Stroke incidence in those of working age has been reported to be increasing significantly, implying strong incentives for research concerning working ability after stroke. This study focused on differences in subjective aspects of work and dimensions of quality of life after having experienced stroke. Sixty-five persons answered a postal questionnaire. The median age at the time of the stroke was

Lifetimes of states in the triaxial strongly deformed bands of Lu-163 have been measured with the Gammasphere spectrometer using the Doppler-shift attenuation method. The bands have been interpreted as wobbling-phonon excitations from the characteristic electromagnetic properties of the transitions connecting the bands. Quadrupole moments are extracted for the zero-phonon yrast band and, for the f

Plastic wave propagation during dynamic buckling of ductile slabs is investigated numerically using a contour plot method (q-plot) showing contours of normalized effective plastic strain rate as a function of time and position. A non-linear finite element method is used to analyse the buckling problem of the elastic-viscoplastic slab. The contour plot method is quite sufficient to depict the overa

The 3s(2)3p(2 3)P(1.2)-3s3p(3) S-5(2) intercombination lines for Si-like Rh have been investigated using the techniques of beam-foil spectroscopy. Two lines have been identified as belonging to these transitions having, however, different wavelengths from what would be expected based on published iso-electronic trends. The identifications suggested here are strengthened by requirements on (a) the

The issue of describing identity of sense relations that are used in contexts of anaphora to express contextually given information is discussed. In text-to-speech applictions, it is important to model given information, both linguistically and computationallly, since it is associated with tone accent patterns that differ from those on new information. The anlysis is illustrated using restricted t

We performed path integral simulations of spin evolution controlled by the Rashba spin-orbit interaction in the semiclassical regime for chaotic and regular quantum dots. The spin polarization dynamics have been found to be strikingly different from the D'yakonov-Perel' (DP) spin relaxation in bulk systems. Also an important distinction has been found between long time spin evolutions in classical

The age and sex specific incidence of tibial condyle fractures and patellar fractures were compared between 1950-55 and 1980-83 in the urban population of Malmo. In elderly women there was an increased incidence over these 30 years for both fracture types.

Vasopressin and oxytocin are synthesised in the hypothalamus and released to the blood stream via the posterior lobe of the hypophysis. Research during later years has shown that these peptides are also produced in other parts of the brain. The secretion to plasma is stimulated by oestrogen, an effect which is counteracted by progestagen. During delivery the fetus can also produce substantial amou

In the course of a screening for cytotoxic Compounds from fungi four new terpenoid metabolites, named dasyscyphins A, B, C, and niveulone were isolated from fermentations of Dasyscyphus niveus strain A0101. While dasyscyphin A (1) exhibited no significant biological activities in our test systems dasyscyphin B (2) and dasyscyphin C (3) showed cytotoxic activities against human (HepG2, Hela S3, U93