Chagasin is a protein produced by Trypanosoma cruzi, the parasite that causes Chagas' disease. This small protein belongs to a recently defined family of cysteine protease inhibitors. Although resembling well-known inhibitors like the cystatins in size (110 amino acid residues) and function (they all inhibit papain-like (Cl family) proteases), it has a unique amino acid sequence and structure. We

Background: Milk products deviate from other carbohydrate-containing foods in that they produce high insulin responses, despite their low GI. The insulinotropic mechanism of milk has not been elucidated. Objective: The objective was to evaluate the effect of common dietary sources of animal or vegetable proteins on concentrations of postprandial blood glucose, insulin, amino acids, and incretin

The surface-to-bulk intensity ratio in Auger electron spectra has been studied in comparison with core-level photoelectron spectra using free argon clusters of sizes ranging over two orders of magnitude. Enhanced surface sensitivity is observed in L2,3M2,3M2.3 Auger electron spectra compared to 2p photoelectron spectra where electrons of similar kinetic energies were recorded. This is discussed in

Although most institutions offer some kind of follow-up to patients operated on for colorectal cancer, its value with respect to prolonged survival has been challenged. However, improved results of liver surgery and chemotherapy make it reasonable to assume that a follow-up programme leading to detection of more asymptomatic recurrences would result in improved survival. Liver metastases and extra

Denna skrift redovisar sjutton exempel på sunda hus - nio daghem och åtta skolor där brukarna upplever ett tillfredsställande inomhusklimat. Samtliga byggnader har nyligen uppförts eller byggts om. Skriften innehåller dokumentation av hur man gått till väga vid arbetet - målsättning, planeringsprocessen, byggnadstekniska fakta, energianvändning och städvanor samt utvärdering av enkäter och mätning

We compared the penetration depth into cancellous bone when pressurizing cement at predetermined pressure levels, and at different times after cement mixing, in 21 arthrotic femoral heads during total hip replacement. To determine the influence of circulating blood on cement penetration, cement was injected into holes drilled into the femoral head before and after osteotomy of the femoral neck. Th

Popular Abstract in Swedish Avhandlingen består av fem upsatser (A-E): I uppsats A undersöks tidsberoende egenskaper hos kölängdsprocessen hos ett kösystem med flera betjänter under mycket allmänna Markovska ankomstprocesser. I uppsats B undersöks en endimensionell slumpvandring som reflekteras i två barriärer. I uppsats C undersöks ruinsannolikheten i en Cramér-Lundberg-modell där utbetalningaThis thesis consists of five papers (A-E). In Paper A, we study transient properties of the queue length process in various queueing settings. We focus on computing the mean and the Laplace transform of the time required for the queue length starting at $x0. We define the loss rate due to the reflection. The main result is sharp asymptotics for the loss rate as $K$ tends to infinity. As a major

A process for the fermentative production of lactic acid from whole-wheat flour consisting of starch and bran containing nutrients is presented and an economical evaluation of the lactic acid production cost performed. Bottlenecks were identified and alternative processes were evaluated and compared. The costs of raw material, the sodium hydroxide in the fermentation step, and the conversion of la

OBJECTIVE: To evaluate the effects of the three commercially available colloid solutions, 6% dextran 70, 6% hydroxyethyl starch (HES) 200/0.5, and 3.5% urea-linked gelatin on permeability for human albumin in a skeletal muscle in vivo model by evaluating their effects on the reflection coefficient for albumin. DESIGN: Controlled laboratory study. SETTING: University research laboratory. SUBJECTS:

Experimental M-shell nickel spectra in the 14.4-16.5 nm region from the JET tokamak (from both divertor and limiter configurations) and from the reversed field pinch RFX have been simulated. These spectra include lines from five ionization states, namely from K-like N-i9+ to P-like Ni13+ ions. For the JET limiter configuration the spectrum upper wavelength limit was higher (18.0 nm) and lines from

Naturally grown fruit-bodies of Suillus luteus, S. bovinus and S. variegatus were subjected to Py-GC. The pyrograms obtained were statistically analysed and classified with a multivariate classification program (SIMCA). The class describing the S. bovinus pyrograms was significantly separated from both the S. luteus and the S. variegatus classes, while these two classes showed some over-lapping wh

New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (SNPs) in 1464 patients with T2D and 1467 matched controls, each characterized for measures of glucose metabolism, lipids, obesity, and blood pressure. With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed