Background/Aims: Endothelin-1 (ET-1) has been implicated in pathologic remodelling and tissue repair processes in the heart. We investigated the effects of ET-1 on growth and collagen synthesis responses in cardiac fibroblasts isolated from human hearts. We also studied the receptor subtype(s) mediating such responses and the factors regulating their expression. Methods: Fibroblasts were isolated

Early Nordic cooperation comprised ideas, programs, even computer blueprints and resulted in rapid progress. Regnecentralen contributed importantly in developing Algol 60. Algol for Facit EDB was used at many sites. Further advances were Datasaab's Algol Genius and the Norwegian Simula project. Regrettably, failure of our compiler companies led to software setbacks. We revisit the Algol debates co

Ground-based FTIR measurements have been performed in the Arctic summer in July 1993 and June 1994 at 79 degrees N to study the zenith column densities of several trace gases in the undisturbed Arctic summer atmosphere. Zenith column densities of H2O, N2O, HNO3, NO2, NO, ClONO2, ClO, HCl, HF, COF2, OCS, SF6, HCN, CH4, C2H6, C2H2, CO, O-3, CFC-12, CFC-22, and CO2 were retrieved by line-by-line calc

OBJECTIVE: The objective of this study was to evaluate whether a regular formula for premature infants supplemented with nucleotides has any influence on plasma lipids and erythrocyte membrane fatty acids. METHODS: Preterm infants fed either human milk supplemented with human milk protein (HM, n = 14), nucleotide-supplemented preterm formula (NF, n = 13), or a regular preterm formula (F, n = 13) w

This study characterizes the high-fat diet-fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female C57BL/6J mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose incr

In boron neutron capture therapy (BNCT) the absorbed dose to the tumor cells and healthy tissues depends critically on the boron uptake. Pronounced individual variations in the uptake patterns have been observed for two boron compounds currently used in clinical trials. This implies a high uncertainty in the determination of the boron dose component. Ln the present work a technique known as prompt

When Harry Sawyerr wrote his essay "What is African Theology?", published first in African Theological Journal, vol. 4 (1971), it appeared from its contents that he was making short comments about James Cone's Black theology that could have disappeared in the midst of more pressing African theological issues. Sawyerr's article was not primarily intended as a critique of Cone's Black theology; inst

This thesis is based on experimental work carried out during the period 1968-1972. The whole investigation is sponsored by the Swedish Council for Building Research and has been performed at the department of Building Materials at the Lund Institute of Technology. The thesis treats the problem frost resistance of building materials, a problem which is far from beeing solved despite much scientifi

Popular Abstract in Swedish Avhandlingen behandlar nätverksmekanisk modellering av mekaniska egenskaper hos cellulosafiberfluff. Cellulosafiberfluff består av fibrer utvunna från trä, och används bl a i blöjor och isoleringsmaterial. En nätverksmekanisk modell är en typ av mikro-mekanisk modell. Principen för denna typ av modell är att man gör antaganden för hur materialet fungerar på mikro-nivåA network mechanics model for cellulose fibre fluff is proposed. 2D and 3D versions of the model have been implemented and the influence of various micro-level parameters on the global mechanical performance has been determined by means of computer simulations. Model networks composed of bonded fibres of arbitrary distribution in length, curvature, cross-section, stiffness and strength were inves

We simulate two-dimensional lattices of pulse-coupled oscillators with random natural frequencies, resembling pacemaker cells in the heart. As coupling increases, this system seems to undergo two phase transitions in the thermodynamic limit. First, the largest cluster of frequency entrained oscillators becomes macroscopic. Second, all oscillators frequency entrain, except possibly some isolated on

Samlingsrecension av BFI-monografier om skräck- och science fiction-film

Single-particle kinetic energy spectra and two-particle small angle correlations of protons (p), deuterons (d) and tritons (t) have been measured simultaneously in 61 A MeV Ar-36 + Al-27, Sn-112 and Sn-124 collisions. Characteristics of the emission sources have been derived from a "source identification plot" (beta(source)-E-CM plot), constructed from the single-particle invariant spectra, and co

PCB concentrations were studied in different soils to determine the spatial variation over a region of approximately 11000 km(2). PCB congener pattern was used to illustrate the spatial differences, as shown by principal component analysis (PCA). The relationship to different soil parameters was studied. PCB concentrations in soil showed a large variation between sampling-areas with median concent

Fluorescence intensity transients of single molecules of the conjugated polymer poly[2-methoxy,5-(2-ethylhexyloxy)-p-phenylene-vinylene] (MEH-PPV) were studied at 15 K. Fluorescence blinking behavior was observed despite the expected low-temperature suppression of energy migration in such disordered molecular systems. Presence of the fluorescence blinking effect at 15K indicates that the single mo