Search results

Filter

Filetype

Your search for "*" yielded 524968 hits

Variation in the PTH2R gene is associated with age-related degenerative changes in the lumbar spine.

In the elderly, degenerative changes in the lumbar spine are common, contributing to falsely elevated bone mineral density (BMD) values. The parathyroid hormone (PTH) system plays an important role in the regulation of bone turnover and we explore the hypothesis that polymorphisms (SNPs) within genes in this pathway (PTH, PTHLH, PTH1R and PTH2R) contribute to degenerative manifestations of the spi

Electrocardiographic Findings in Systemic Lupus Erythematosus: Data From an International Inception Cohort

Objective. To estimate the early prevalence of various electrocardiographic (EKG) abnormalities in patients with systemic lupus erythematosus (SLE) and to evaluate possible associations between repolarization changes (increased corrected QT [QTc] and QT dispersion [QTd]) and clinical and laboratory variables, including the anti-Ro/SSA level and specificity (52 or 60 kd). Methods. We studied adult

Laser-produced plasma EUV source based on tin-rich, thin-layer targets

In this paper a new approach to a laser-produced plasma EUV source based on a tin target is presented. A thin layer of pure tin and composite layers consisting of Sn with Si, SiO and LiF are investigated. The target composed of several thin layers produces less debris than the other targets and provides a conversion efficiency (CE) in the 13.5-nm +/- 1% band at least comparable to the CE for the p

SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia.

Cooperative dependencies between mutant oncoproteins and wild-type proteins are critical in cancer pathogenesis and therapy resistance. Although spleen tyrosine kinase (SYK) has been implicated in hematologic malignancies, it is rarely mutated. We used kinase activity profiling to identify collaborators of SYK in acute myeloid leukemia (AML) and determined that FMS-like tyrosine kinase 3 (FLT3) is

Potential Determining Salts in Microemulsions: Interfacial Distribution and Effect on the Phase Behavior

In this work we consider potential determining salts, also referred to as phase transfer agents for a future objective of electrochemistry at the oil-water interface in microemulsions. We have studied these salts, composed of a hydrophilic and a hydrophobic ion, in microemulsion stabilized by nonionic surfactants with an oligo ethylene oxide headgroup. NMR measurements show that the salts preferen

The Significance of Walking from the Perspective of People with Parkinson's Disease.

Background: Parkinson's disease (PD) is associated with progressive mobility and walking difficulties. Although these aspects have been found to be central from a patient perspective, the perceived significance of walking is less well understood. Objective: To explore the significance of walking as perceived and experienced by individuals with PD. Methods: Eleven persons with PD (seven men; median

Human Papillomavirus Antibody Reference Reagents for Use in Postvaccination Surveillance Serology

Suitably controlled serosurveillance surveys are essential for evaluating human papillomavirus (HPV) immunization programs. A panel of plasma samples from 18-year-old females was assembled, the majority of the samples being from recipients of the bivalent HPV vaccine. Antibody specificities were evaluated by three independent laboratories, and 3 pools that displayed no antibodies to any HPV type t

Validity of the Swedish Rectal Cancer Registry for patients treated with major abdominal surgery between 1995 and 1997.

Background. Founded in 1995, the Swedish Rectal Cancer Registry (SRCR) is frequently used for rectal cancer research. However, the validity of the registry has not been extensively studied. This study aims to validate a large amount of registry data to assess SRCR quality. Material and methods. The study comprises 906 patients treated with major abdominal surgery registered in the SRCR between 199

Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at root s=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy root s = 8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb(-1). No

Photodissociation of Bromobenzene in Solution.

The photodissociation of bromobenzene in solution was investigated with ultrafast transient absorption spectroscopy following excitation at 266 nm. Ab initio calculations of lower singlet and triplet states were performed in order to guide the interpretations. The main feature of the kinetics measured between 300 and 930 nm in acetonitrile is a 9±1 ps decay, which we mainly assign to predissociati

Apamin inhibits NO-induced relaxation of the spontaneous contractile activity of the myometrium from non-pregnant women

There is now considerable evidence for the involvement of K+ channels in nitric oxide (NO) induced relaxation of smooth muscles including the myometrium. In order to assess whether apamin-sensitive K+ channels play a role in NO - induced relaxation of the human uterus, we have studied the effect of specific blockers of these channels on the relaxation of myometrium from non-pregnant women. In vitr

Simplicity and maximal commutative subalgebras of twisted generalized Weyl algebras

In this paper we prove three theorems about twisted generalized Weyl algebras (TGWAs). First, we show that each non-zero ideal of a TGWA has non-zero intersection with the centralizer of the distinguished subalgebra R. This is analogous to earlier results known to hold for crystalline graded rings. Second, we give necessary and sufficient conditions for the centralizer of R to be commutative (henc

Photocurrent Generation from Thylakoid Membranes on Osmium-Redox-Polymer-Modified Electrodes.

Thylakoid membranes (TMs) are uniquely suited for photosynthesis owing to their distinctive structure and composition. Substantial efforts have been directed towards use of isolated photosynthetic reaction centers (PRCs) for solar energy harvesting, however, few studies investigate the communication between whole TMs and electrode surfaces, due to their complex structure. Here we report on a promi

Food and health: individual, cultural, or scientific matters?

In personalized nutrition, food is a tool for good health, implying an instrumental relationship between food and health. Food receives a secondary value, while health would appear to be a descriptive biological concept. This article gives an introduction to cultural understandings of food and health. The wider definition of food and health is explored in relation to the commonly used scientific a