Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. My studies show that agonist-promoted internalization and postendocytic sorting determine the degree of resensitization of opioid m (MOR) and d (DOR) receptor

The partitioning of hydrophobic amino acids and oligopeptides in the Pluronic P105-dextran-water system has been studied. Pluronic P105 is a member of a family of triblock copolymers with the structure PEO-PPO-PEO, where PEO is poly(ethylene oxide) and PPO poly(propylene oxide). The partitioning was studied for tryptophan, phenylalanine and di- and tri-peptides composed of these amino acids at 5 a

In order to be competitive, it is crucial for cellular operators to use their resources, such as spectrum and equipment, as effectively as possible. A more efficient usage of the available resources enables the operators to reduce the necessary deployment cost and/or to improve the offered Quality of Service in their networks. The concept of resource management includes among other things admissi

Packet loss concealment (PLC) at a receiver has a substantial effect on the speech quality in Voice over IP. Most conventional PLC systems have largely relied upon variations of signal repetition and overlap-add interpolation which can produce speech signals that do not follow the larger overall statistical trends. In this paper, we demonstrate how Hidden Markov Models can be utilized to effect PL

Objective To study the characteristics of the infants born to women who have used anti-asthmatic drugs during pregnancy. Material and methods Various characteristics of infants with mothers who had reported the use of anti-asthmatic drugs in early pregnancy (n=24,750) or had such drugs prescribed later during pregnancy by a maternity health care centre (n=763) were identified from the Swedish Medi

Popular Abstract in Swedish Klumpfot är en medfödd fotfelställning, som drabbar 1 av 1000 barn. Behandlingen består initialt av korrektion av felställningen, genom töjning och eventuellt operation. Det finns flera alternativa metoder att genomföra töjningar, och flera alternativa operationsmetoder. När felställningen korrigerats övergår behandlingen till att bibehålla det uppnådda läget med hjälp Clubfoot is a congenital disorder, affecting about one of 1000 children. Treatment consists of initial correction of the deformity, followed by prolonged orthosis treatment to maintain the correction obtained. There are several different treatment options. Outcome studies, using reliable and valid instruments are rare. In this thesis an assessment instrument, Clubfoot Assessment Protocol (CAP) wa

Studies songs of worship from Taizé from the point of view of their spirituality. The definition of spirituality given by Hans Urs von Balthasar is used.

The overall purpose with this work is to study the flow past particles and droplets using numerical simulations. Especially the interaction among particles and droplets have been a main objective as the results are to be used in order to improve already existing spray models. In order to represent the particulate and droplet phase, the Volume of Fluid (VOF) and the Volume of Solid (VOS) methods ar

Organ transplantation provides a treatment of end-stage disease primarily in the kidney, liver and heart. The immunosuppressive treatment regimens of today efficiently prevent early acute rejection; however the long-term survival has not improved to the same extent. Within months/years the majority of transplanted organs develop chronic allograft dysfunction (CAD), associated with fibrosis and int

The study deals with strain on the family system, as well as the level of coping and types of coping behavior of the parents, in families with a child diagnosed as having an autistic spectrum disorder (ASD) as compared to families in a control group. Thirty-seven families and 66 parents were involved in each case, and four psychological tests were used. It was found that lower levels of coping wer

Positron annihilation lifetime spectroscopy (PALS) was performed on a series of polydimethylsiloxane (PDMS)/fumed silicon dioxide (SiO2) composites at temperatures between -185 and 100degreesC to study the effect of filler content and filler particle size on the free volume properties and the positron annihilation characteristics. The glass transition behavior of the PDMS/SiO2 composites was deter

This paper describes a project course that focuses on the design of analog and mixed signal circuits through a systematic top down design flow. In the project, the student will be involved in the planning, modeling, circuit level design, physical level implementation and measurement verification of for example a successive approximation (SA) ADC or a class-D audio amplifier. Throughout the project