Search results

We previously reported that insulin stimulation of human platelets induces serine phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase (cGI-PDE). Here, we describe methods to detect and partially purify an insulin-stimulated cGI-PDE kinase (cGI-PDE ISK) from lysates of platelets incubated with insulin. Incubation of human platelets with 10(-8) M insulin increased cGI-PDE ISK

Popular Abstract in Swedish Bakgrund Denna studie är en undersökning av barns musikskapande med synthesizer och dator. I studien deltog nio barn i åttaårsåldern. Musik utgör en viktig del i barns och ungdomars vardag och den stora exponering för musik som sker i vårt samhälle innebär att ingen är någon musikalisk nybörjare. Det är väl känt att barn kan skapa musik på egen hand, mest är det dock bToday’s children live in a world where music in all its different forms has become a significant factor in their everyday life. From earlier research we know that young children are able to create music by singing and using musical instruments. The present study was undertaken with eight-year-old children in school year 2 in order to investigate the children’s composing and composition processes u

Chloroplasts isolated from a plant species, Dimorphotheca pluvialis Moench (Asteraceae), grown under visible light without supplementary UV-B radiation, have poor grana development. The dominant components in the membrane organizations are doublets and triplets of stroma lamellae. However, such chloroplasts possess the capacity for electron transfer through the whole photosynthetic chain, based on

BACKGROUND: Persistent organochlorine pollutants (POPs) may interfere with reproductive function but direct evidence in humans is very limited. METHODS: Fertility was examined in four regions with contrasting blood levels of POPs. Pregnant women and their partners in Warsaw (Poland), Kharkiv (Ukraine) and Greenland were consecutively enrolled during antenatal visits. Swedish fishermen and their sp

Three isoforms of the major birch pollen allergen, Bet v, 1 from Betula verrucosa have been expressed as recombinant proteins in E. coli and purified. The immunochemical properties of recombinant isoforms (rBet v 1) differed on immunoblots when compared using Mabs and birch pollen allergic patients serum IgE. 2-D gel analysis showed that recombinant isoforms with different epitope structure can fo

Abstract in Undetermined Not available

A selective pressurized liquid extraction (SPLE) procedure capable of performing simultaneous extraction and clean-up has been demonstrated for multi-residue analysis of organochlorine pesticides (OCPs) in soil. The final method was performed at 100 degrees C for 3 x 10 min using acetone/n-heptane (1:1, v/v). Florisil was placed inside the extraction cell downstream the sample to remove interferin

The development of inhibitory antibodies against coagulation factor VIII (FVIII) in patients with mild haemophilia A is uncommon. We describe here two families in which three or two members have developed inhibitors, suggesting a familial predisposition. The mutations found, in the A2 (Arg593Cys) and C1 domains (Tyr2105Cys), have been reported to give rise to inhibitor development in single indivi

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

The Arctic has become an important region in which to assess the impacts of current climate variability and amplification of projected global warming. This is because i) the Arctic has experienced considerable warming in recent decades (an average of about 3°C and between 4° and 5°C over much of the landmass); i) climate projections suggest a continuation of the warming trend with an increase in me

To clarify the effects of solid fat and liquid oil on dough in more detail in a simpler system, gluten-starch doughs with different gluten contents were investigated. The results from rheological measurements indicate that dough with a higher starch content has less resistance to strain and dough with a lower starch content has a rubber-like structure. The effects of the physical state of nonpolar

The anti-inflammatory effect of purified honey bee venom (HBV) was studied using a recently described animal model in which preformed immune complexes were injected into rabbit knee-joints. As little as a single injection of 1.2 micrograms HBV/kg body weight subcutaneously significantly reduced the immune complex induced joint inflammation as measured by reduction in leukocyte counts in the joint